Pattern of Perioperative Antibiotic Use in Otorhinolaryngology-Head and Neck Surgery at Third Referral Hospital In Surabaya
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Introduction: Surgical site infection (SSI) often occurs in operation. SSI frequently only affects the superficial tissues, but some more serious infections can affect the deeper tissues or other parts of the body. The majority of SSIs become apparent within 30 days of an operative procedure, when a prosthetic implant is used, SSI may occur several months after the operation. To minimize surgical site infection occurrence, prophylaxis antibiotic is often used. The aim of the study is to evaluate the use of perioperative antibiotics for otorhinolaryngology surgery in third referral hospital in Surabaya.
Methods: This study was a retrospective cross-sectional method through the medical record of patients cases from December 2017 to January 2018. All data about sex, age, diagnosis, wound classification, surgical intervention including ICD 9 CM codes, and antibiotics regiments are presented descriptively.
Results: Of total 68 patients, 42 (61.8%) were male and 46 (61.8%) were aged 18-65 years old. The most common type of operation was clean surgery 52 (76.5%). The most common prophylactic antibiotic was cefazoline 25 (96.6%).
Conclusion: Most of the performed surgery was clean surgery. The use of perioperative antibiotics in most performed operations was in accordance with existing literature. The most widely used prophylactic and therapeutic antibiotic was cefazoline and ceftriaxone, respectively. Further research about risk factor of SSI, the use of prophylaxis antibiotic, and bacterial profile with more samples is needed for more accurate results.
Nichols RL. Preventing Surgical Site Infections : A Surgeon ' s Perspective. 2001; 7: 220–224.
Owens CD, Stoessel K. Surgical site infections : epidemiology , microbiology and prevention. J Hosp Infect 2008; 70: 3–10.
WHO. Prevention of hospital-acquired infections World Health Organization.
Yuwono. Pengaruh Beberapa Faktor Risiko Terhadap Kejadian Surgical Site Infection ( SSI ) Pada Pasien Laparotomi Emergensi. 2013; 15–25.
Marsanto AE, Paraton H, Prasetyo B. Pattern of disease and type of operation of Surgical Site Infection in obstetrics and gynecology at Dr Soetomo Hospital , Surabaya , Indonesia. 2019; 27: 49–55.
Larson EL, Pearson ML, Lee JT, et al. Guideline For Prevention Of Surgical Site, 1999.
National Collaborating Centre for Women's and Children's Health. Surgical site infection prevention and treatment of. 2008.
Indonesia MKR. Peraturan Menteri Kesehatan Republik Indonesia Nomor 2406/MENKES/PER/XII/2011. 2011.
Centers for Disease Control and Prevention. Antibiotic Resistance Threats in the United States, 2019.
Kijima T, Masuda H, Yoshida S, et al. Antimicrobial Prophylaxis is Not Necessary in Clean Category Minimally Invasive Surgery for Renal and Adrenal Tumors: A Prospective Study of 373 Consecutive Patients. URL 2012; 80: 570–575.
Myers E, Snyderman C. Operative Otolaryngology Head and Neck Surgery. Elsevier Health Sciences, 2018.
Johannes S, Aghdassi S, Schröder C, et al. Gender-related risk factors for surgical site infections . Results from 10 years of surveillance in Germany. 2019; 1–8.
Sommer M. Prevalence and Predictors of Postoperative Pain After Ear, Nose, and Throat Surgery. 2015; 135: 124–130.
Dominioni L, Imperatori A, Rotolo N, et al. Risk Factors for Surgical Infections. 2006; 7: 9–13.
University of IOWA Health Care. Microdirect Laryngoscopy (Suspension Microlaryngoscopy or Direct Laryngoscopy), https://medicine.uiowa.edu/iowaprotocols/microdirect-laryngoscopy-suspension-microlaryngoscopy-or-direct-laryngoscopy (2018, accessed 10 September 2019).
Gandhi A, Brodsky L, Ballow M. Benefits of Antibiotic Prophylaxis in Children with Chronic Sinusitis : Assessment of Outcome Predictors. 2016; 37–43.
Pierce NE, Antonelli PJ. Efficacy of Antibiotic Prophylaxis Prior to Tympanoplasty for Contaminated Cholesteatoma. 2016; 1–4.
Stephanie H C, Alexander S. K. Perioperative Antibiotics in Thoracic Surgery Stephanie. 2013; 22: 35–45.
Ruol A, Bertiato G, Boscarino S, et al. Short-Term Prophylaxis with Ceftriaxone Plus Metronidazole in Esophageal Cancer Surgery Short-Term Prophylaxis with Ceftriaxone Plus Metronidazole in Esophageal Cancer Surgery. 9478. Epub ahead of print 2017. DOI: 10.1080/1120009X.2000.11782304.
Richards DM, Heel RC, Brogden RN, et al. Ceftriaxone A Review of its Antibacterial Activity , Pharmacological Properties and Therapeutic Use. 1984; 527: 469–527.
Chandra RK, Conley DB, Kern RC. Prophylactic i.v. antibiotics in functional endoscopic sinus surgery: Trends and attitudes of the American Rhinologic Society membership. 2016; 23: 448–450.
Amri G, Matulatan F, Widodo A. Profil Penggunaan Antibiotik Pada Kasus Bedah Di IRD Rsud Dr. Soetomo Surabaya.
ASHP, IDSA, SIS, et al. Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery. In: ASHP Therapeutic Guidelines. 2013.
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