Challenging Therapy In Pregnant Woman With Systemic Lupus Erythematosus (SLE) and Chronic Hepatitis B

Choirina Windradi, Awalia Awalia

= http://dx.doi.org/10.20473/bhsj.v3i1.19198
Abstract views = 93 times | downloads = 98 times

Abstract


Systemic Lupus Erythematosus (SLE) is an autoimmune disease that attacks various body systems, especially in women of reproductive age. Therefore, patients who are planning a pregnancy or are pregnant need to assess the risk and predicts of disease activity during pregnancy. The most common complications of SLE in pregnancy are SLE disease activity, preterm delivery, preeclampsia and preganancy loss. Here, we report a pregnant SLE patient with co-infection hepatitis B. As the consequence of treated with immunosuppressant agent, both disease progression and immunosupressant agent can lead to severe infection. Furthermore, perinatal transmission is the most common form of transmission of hepatitis B. Finally, proper management  could save mother and newborn.


Keywords


systemic lupus erythematosus; hepatitis B; pregnancy

Full Text:

PDF

References


Stojan G, Baer AN. Flares of systemic lupus erythematosus during pregnancy and the puerperium: Prevention, diagnosis and management. Expert Rev Clin Immunol. 2012;8(5):439–53.

Perhimpunan Reumatologi In. . 2019. Jakarta: Perhimpunan Reumatologi Indonesia; Indonesia.

Yang MJ, Chen CY, Chang WH, Tseng JY, Yeh CC. Pregnancy outcome of systemic lupus erythematosus in relation to lupus activity before and during pregnancy. J Chinese Med Assoc [Internet]. 2015;78(4):235–40. Available from: http://dx.doi.org/10.1016/j.jcma.2014.11.008

Ruiz-Irastorza G, Khamashta MA. Evaluation of systemic lupus erythematosus activity during pregnancy. Lupus. 2004;13(9):679–82.

Gonzalez SA, Perrillo RP. Hepatitis B Virus Reactivation in the Setting of Cancer Chemotherapy and Other Immunosuppressive Drug Therapy. Clin Infect Dis. 2016;62(May):S306–13.

Knight CL, Nelson-Piercy C. Management of systemic lupus erythematosus during pregnancy: Challenges and solutions. Open Access Rheumatol Res Rev. 2017;9:37–53.

Olesińska M, Więsik-Szewczyk E, Chwalińska-Sadowska H. Evaluation of systemic lupus erythematosus activity during pregnancy. Polish Arch Intern Med. 2018;117(7):312–6.

Cauldwell M, Nelson-Piercy C. Maternal and fetal complications of systemic lupus erythematosus. Obstet Gynaecol. 2012;14(3):167–74.

Terrault NA, Bzowej NH, Chang KM, Hwang JP, Jonas MM, Murad MH. AASLD guidelines for treatment of chronic hepatitis B. Hepatology. 2016;63(1):261–83.

Lampertico P, Agarwal K, Berg T, Buti M, Janssen HLA, Papatheodoridis G, et al. EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection. J Hepatol. 2017;67(2):370–98.

Idilman R. The summarized of EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection. Turkish J Gastroenterol. 2017;28(5):412–6.


Refbacks

  • There are currently no refbacks.




Copyright (c) 2020 Biomolecular and Health Science Journal

INDEXING BY:

Creative Commons License

This Journal (E-ISSN:2620-8636) is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

View BHSJ Stats