A 40-year-old Woman with Hypercalcemia Crisis Caused by Bone Metastasis in Stage IV Breast Cancer

Breast cancer bone metastasis hypercalcemia crisis

Authors

  • Wiharjo Hadisuwarno Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
  • Merlyna Savitri
    merlyna.savitri@gmail.com
    Medical Hematology Oncology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital Surabaya, Indonesia
  • Ami Ashariati Medical Hematology Oncology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital Surabaya, Indonesia
  • S. Ugroseno Yudho Bintoro Medical Hematology Oncology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital Surabaya, Indonesia
  • M. Noor Diansyah Medical Hematology Oncology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital Surabaya, Indonesia
  • Putu Niken Ayu Amrita Medical Hematology Oncology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital Surabaya, Indonesia
  • Pradana Zaky Romadhon Medical Hematology Oncology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital Surabaya, Indonesia
October 31, 2021

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Breast cancer is still global burden especially for woman with 2.3 million cases every year dan 15% mortality among cancer diseases. In developing countries, most of the cases are diagnosed at terminal stage when metastasis already found. Bone metastasis is the highest among other metastasis sites such as: lung, liver and brain. Bone metastasis will cause hypercalcemia and bone pain as complications.  Both will gradually decrease patient's quality of life. Comprehensive and holistic management for these complications will reduce deterioration and hopefully increase patient's quality of life even they were at terminal stage. We describe a 40-year-old woman who got hypercalcemia crisis. Hypercalcemia usually manifest as a consequence of other diseases. Epidemiologically, majority come from metastasis, but can be other diseases, such as multiple myeloma. Interestingly, during medical investigation through her medical history, and physical examination, and laboratory examinations, we conclude that her hypercalcemia crisis was caused by bone metastasis from breast cancer.

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