Str Locus Mutations In Paternity Case
Downloads
DNA analysis is widely applied in solving forensic cases, especially Short Tandem Repat (STR) because of its advantages. In identifying the individual, the National Police compared the individual's DNA with that of his parents. Each anal has a pair of DNA fragments of which half are inherited by the father and the remainder by the mother according to Mendel's Law of Segregation. In this study, we compared DNA typing between the child and the mother with the help of PCR extracted by the Chelex method to find the mother fragment and obtain the father fragment. A child is the biological child of the alleged father if he or she has less than 2 exclusion STR loci. The results of this study revealed that all paternal fragments from the child were identical to the DNA fragments of the alleged father, except for one locus, namely CSF1PO which had a mutation. Mutations in the STR locus lower the paternity index, although it can still be concluded that the child is the biological child of the alleged father.
Keywords: Paternity Test, DNA, STR, Mutation
Copyright (c) 2022 Jurnal Biosains Pascasarjana
![Creative Commons License](http://i.creativecommons.org/l/by-sa/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Authors who publish with this journal agree to the following terms:
- The copyright of this journal belongs to the Editorial Board and Journal Manager with the author's knowledge, while the moral right of the publication belong to the author.
- The formal legal aspect of journal publication accessibility refers to the Creative Commons Attribution-Share Alike (CC BY-SA).
- Every publication (print/electronic) is open access for educational, research, and library purposes. In addition to the objectives mentioned above, the editorial board is not responsible for copyright infringement