Folia Medica Indonesiana

Rehabilitation Impact of Vivifrail Exercise Program Type C on the Cognitive Function of Pre-Frail Elderly People in the Community

2024-08-31T15:59:34+07:00

Highlights:
1. This study emphasizes the importance of providing physical exercises to pre-frail elderly individuals, especially in a community setting.
2. This study establishes a foundation for future research to explore the relationship between physical exercise, particularly the Vivifrail Type C Protocol, and cognitive function in pre-frail elderly individuals.

Abstract

Frailty is a clinical syndrome that increases vulnerability, potentially leading to disability or death. The pre-frail phase is ideal for preventing frailty and improving quality-adjusted life years, particularly through physical exercises that reduce the risk of dementia and cognitive impairment. Multicomponent exercises, such as the Vivifrail Exercise Program, may enhance cognitive function and daily independence by preventing and mitigating frailty through tailored routines. However, its impact on cognitive function in pre-frail elderly people had not been well studied. This study aimed to determine the effect of the Vivifrail Exercise Program Type C on the cognitive function of pre-frail elderly people. This study was a quasi-experiment with a non-randomized control group pretest-posttest design. The sample was chosen by the quota sampling method. Twenty-seven subjects were analyzed, comprising 16 individuals in the exercise group and 11 individuals in the control group. The exercise group participated in the Vivivfrail Type C Exercise Program, with 45-minute sessions conducted biweekly for 12 weeks. The evaluated parameters included the Montreal Cognitive Assessment-Indonesian Version (MoCA-INA) and the Loewenstein Occupational Therapy Cognitive Assessment (LOTCA). The statistical analysis utilized the Kruskal-Wallis test, followed by the post-hoc Mann-Whitney test and independent t-test (p<0.05). A path analysis was performed using simple linear regression. The subjects' average ages were 72.2 years in the control group and 67.47 years in the exercise group. The Vivifrail Exercises Program Type C significantly improved the MoCA-INA scores from 20.25 to 24.06. It also increased the LOTCA scores in several domains, i.e., thinking operations and visual perception. The exercise group demonstrated more improvement than the control group (p=0.032). An enhancement in cognitive function was particularly observed in elderly women with pre-frailty. In conclusion, the Vivifrail Exercise Program Type C can help improve the cognitive function of the elderly within the community.

Larvicidal Effect of Breadfruit (Artocarpus altilis) Flower Extract Against Aedes aegypti

2024-08-30T13:05:01+07:00

Highlights:
1. This study attempted an experiment on the novel invention of a naturally sourced larvacide, specifically breadfruit (Artocarpus atilis) flower extract, against Aedes aegepti.
2. The findings of this study suggest that breadfruit flower extract can serve as an effective larvacide, as evident by an increased mortality rate of Aedes aegepti larvae.

Abstract

Dengue hemorrhagic fever remains a major problem in Indonesia. The mosquito that spreads this disease is the Aedes aegypti species. The use of larvicides is a viable method to inhibit the growth of larvae into adult mosquitoes. The flowers of breadfruits (Artocarpus atilis) have long been used as a natural mosquito killer. The objectives of this study were to determine the lethal dose 50 (LC50) of breadfruit flower extract and to analyze its potential as a larvicide against stage 2–3 instar Aedes aegypti larvae. In this true experimental research, each of four treatment groups was administered with breadfruit flower extracts at concentrations of 25, 50, 75, and 90 ppm, respectively. The positive control group was treated with temephos (Abate), while the negative control group received no treatment. Larval mortality was recorded at 1 hour, 2 hours, 3 hours, 4 hours post-intervention. The observed larval deaths were compared among the groups. Quantitative data encompassing the larval mortality in each group were analyzed using the repetitive analysis of variance (ANOVA) and the probit test with minimum p value <0.05. The results indicated that the LC50 value of breadfruit flower extract was 52.67–54.12 ppm. The doses of 50 ppm, 75 ppm and 90 ppm were effective in killing Aedes aegypti larvae. In conclusion, breadfruit flower extract of 50 ppm and higher can effectively kill Aedes aegypti larvae.

Total Plate Count Analysis and Food-Contaminating Bacterial Identification of Smoked Tatihu (Thunnus albacares) Sold in Several Traditional Markets in Ambon, Indonesia

2024-08-23T16:06:01+07:00

Highlights:
1. This research provides important information regarding the food safety of smoked tatihu (yellowfin tuna) sold in several traditional markets in Ambon, Indonesia.
2. We find that smoked tatihu fish samples examined at 2 of 3 traditional markets in Ambon city are unsafe for consumption according to the Indonesian National Standard due to bacterial contamination.
3. The findings indicate that smoked fish can be contaminated by Gram-positive bacteria, such as Staphylococcus gallinarum, Staphylococcus sciuri, Rothia kristinae, and Staphylococcus pseudintermedius.

Abstract

The large marine area and abundant fish resources of Maluku Province, Indonesia, are in contrast to the poor hygiene of its traditional markets, which can cause microbial contamination and taint processed products, such as smoked tatihu (yellowfin tuna). In Ambon city, Maluku, Indonesia, no research had been conducted concerning total plate count analysis and food-contaminating bacterial identification that could guarantee the microbiological safety of smoked tatihu. Therefore, this study aimed to assess the microbiological quality of smoked tatihu according to Indonesian National Standards (INS 2725:2013) and to identify any presence of food-contaminating bacteria. This research was a quantitative descriptive study with a true experimental laboratory approach. The samples used were smoked tatihu collected from three traditional markets in Ambon, Indonesia. The spread plate method was used in the isolation process, while the total plate count analysis was performed to estimate the quantity of colonies on each petri dish. Bacterial identification was carried out macroscopically and microscopically. The microscopic identification involved Gram staining to determine the shape and color of the bacteria. Additionally, the bioMérieux VITEK 2 Compact system was utilized for biochemical identification to ascertain the species of bacteria present. The results revealed that the colony counts in smoked tatihu from the Mardika market and Hative Kecil market were 1.1 x 10⁴ CFU/g and 8.2 x 10⁶ CFU/g, respectively. However, smoked tatihu from the Batu Meja market had an excessive number of colonies that were difficult to quantify. The contaminating bacteria were identified as Staphylococcus gallinarum, Staphylococcus sciuri, Rothia kristinae, and Staphylococcus pseudintermedius. In conclusion, smoked tatihu fish from the Mardika market are considered safe for consumption as the microbiological parameters do not exceed the Indonesian National Standards, whereas those obtained from the Hative Kecil and Batu Meja markets are unsafe for consumption due to the excessive presence of food-contaminating bacteria.

Sexual Abuse and Neglect during Childhood are Associated with an Increased Prevalence of Mental Health Problems among University Students in Surakarta, Indonesia

2024-08-06T07:50:04+07:00

Hihglights:

1. This study reiterates the long-term negative impact of childhood trauma on young adults' mental health.
2. This study contributes to the prevention of mental disorders through the identification of risk factors associated with mental health problems.

Abstract

The prevalence of mental health problems is a global public health concern. Young adults, such as university students, are highly vulnerable to the onset of mental health problems due to biological, psychological, and social factors. In particular, abusive and traumatic experiences during childhood may increase the risk of developing mental health problems during adulthood. The prevalence of child abuse cases in Indonesia is concerning. This abuse includes physical, emotional, and sexual abuse, in addition to neglect. This study aimed to assess the relationship between the occurrence of mental disorder symptoms during young adulthood and the preceding child abuse. A total of 191 undergraduate students in Surakarta, Indonesia, participated in this study. The participants completed the Child Abuse and Trauma Scale (CATS) for the evaluation of maltreatment experienced during childhood and adolescence as well as the Self-Reporting Questionnaire-20 (SRQ-20) for the measurement of mental health problem symptoms. The association of the degree of child abuse and trauma with mental health problems was analyzed using a logistic regression test, which was selected because the dependent variable (mental health problems) had binary outcomes. The level of statistical significance was set at p<0.05. We found that 33% of the participants reported mental health problems. In addition, sexual abuse and neglect were found to be associated with mental health problems. The analysis of the sexual abuse variable revealed a statistically significant value of p=0.03, an odds ratio (OR) of 1.39, and a 95% confidence interval (CI) of 1.03-1.88. Additionally, the analysis of the neglect variable yielded comparable results with values of p=0.03, OR=1.26, and 95% CI=1.02-1.55. Our findings suggest that child abuse, particularly sexual abuse and neglect, may have a long-term deleterious impact on an individual’s mental health.

Bacterial Profiles and Antibiotic Resistance in Chronic Obstructive Pulmonary Disease Patients with Exacerbation and Type 2 Respiratory Failure at Adam Malik General Hospital

2024-08-04T16:11:44+07:00

Highlights:
1. This study provides a comprehensive analysis of various factors such as age, sex, education, occupation, BMI, and comorbidities, and their relationship with bacterial infections in COPD patients experiencing exacerbation and type 2 respiratory failure.
2. While the COPD patients experiencing exacerbation did not exhibit resistance to linezolid and vancomycin, they demonstrated specific antibiotic resistance patterns characterized by high resistance rates to commonly used antibiotics such as meropenem and amikacin.
3. The findings enhance the understanding of the complex interplay of factors influencing infection patterns in this patient population.

Abstract

Chronic obstructive pulmonary disease (COPD) is a prevalent condition characterized by persistent respiratory symptoms and airflow limitation. Bacterial infections may trigger COPD exacerbations, leading to more severe symptoms as well as increased morbidity and mortality rates. This study aimed to investigate the bacterial profiles and antibiotic resistance in COPD patients who had experienced exacerbation and type 2 respiratory failure at Adam Malik Central General Hospital, Medan, Indonesia. This retrospective study utilized medical records spanning from January 1, 2020, to December 1, 2022. The sample included patients aged 40–90 years who had experienced COPD exacerbation and type 2 respiratory failure. The exclusion criteria were patients who had received antibiotic therapy within 48 hours before admission, were severely immunocompromised, and had severe malignancy. The analysis results were presented in the form of means, standard deviations, and frequency distributions. Additionally, an analysis of the relationship between the categorical variables was performed using the Chi-squared test (p<0.05). The study analyzed 25 subjects with an average age of 63.6 years, primarily consisting of men (84%). It was shown that severe exacerbations were prevalent (92%), accompanied by the presence of common comorbidities including pneumonia (52%), diabetes mellitus (32%), and other non-communicable diseases (44%). Bacterial growth was observed in 76% of the subjects, predominantly involving Gram-negative bacteria (89.4%). Klebsiella pneumoniae (26.3%) and Pseudomonas aeruginosa (21.1%) were the most frequently isolated species. The antibiotic resistance patterns indicated that meropenem and amikacin had the highest resistance rates (100%). Cefepime, ertapenem, and gentamicin exhibited notable resistance rates of 66.7%, 66.7%, and 75.0%, respectively. This study highlights the high prevalence of Gram-negative bacteria and significant antibiotic resistance in COPD patients who exhibit exacerbation and type 2 respiratory failure.