Blood Transfusion Practices at The Intensive Observation Unit (Ruang Observasi Intensif/ROI) of Dr. Soetomo General Academic Hospital Surabaya
Downloads
Introduction: Blood transfusion is the process of transferring blood or its components, such as red blood cells, plasma, and platelets, from donor to recipient. The major reason for blood transfusion is anemia and bleeding, frequently seen in critically ill trauma patients in Intensive Observation Unit (Ruang Observasi Intensif/ROI). One of the most prevalent causes of potentially preventable death in trauma patients is uncontrolled bleeding. In addition to controlling the bleeding by surgical or interventional procedures, blood transfusion is carried out to maintain oxygenation to tissue, preventing organ dysfunction due to hypoxia. Objective: This study aimed to determine the profile of blood transfusion carried out on the patients in the ROI of Dr. Soetomo General Academic Hospital. Methods: This retrospective descriptive study was conducted using medical records involving 258 patients who met the inclusion criteria. Results: The result showed that the majority of patients were female, aged 26-35 years, had blood type O, and Rhesus (Rh)-positive, accounting for 55.04%, 26.36%, 39.53%, and 100%, respectively. The most common indication for transfusion was anemia, with a percentage of 69.10%, particularly severe anemia, accounting for 48.45%. Furthermore, 57.36% of patients were from the surgery department, and 36.05% stayed in ROI for 2-3 days. The most common blood component and unit transfused was packed red blood cells (PRC), with a percentage of 57.50% and 439 units at 47.82%. Most of the transfusions, with a percentage of 37.80%, were carried out within 3-4 hours. Some patients were experiencing pruritus, febrile, urticaria, and chills, accounting for 0.39%, 0.39%, 0.39%, and 0.39%, respectively. Conclusion: Understanding transfusion practices, including blood type distribution, can prevent blood shortage, estimate the need for blood among ROI patients in Dr. Soetomo General Academic Hospital, and further ensure that all transfusions are ABO and Rh compatible.
Sutjahjo A. Dasar-dasar ilmu penyakit dalam. Surabaya: Airlangga University Press (AUP); 2015.
Okello CD, Shih AW, Angucia B, Kiwanuka N, Heddle N., et al., mortality and its associated factors in transfused patients at a tertiary hospital in Uganda. PLoS ONE. 2022;17(9).
Wardati, Nur'aini, Hadi AJ. Faktor Yang Mempengaruhi Perilaku Donor Darah di Unit Transfusi Darah Rs Dr. Fauziah Bireuen. MPPKI. 2019;2(3):181–185.
Bruin S, Eggermont D, Bruggen R, Korte D, Scheeren TWL. et al., Transfusion practice in the bleeding critically ill: An international online survey-The TRACE-2 survey. Transfusion. 2022;62(2):324-335.
Manen L, Hezel M, Boshuizen M, Straat M, Man AME. et al., Effect of red blood cell transfusion on inflammation, endothelial cell activation and coagulation in the critically ill. Vox Sanguinis. 2022;117(1):64-70.
Regulation of the Minister of Health of the Republic of Indonesia No. 91 of 2015 on Standar of Blood Transfusion Services. Jakarta. (December 31, 2015)
Marshall JC, Bosco L, Adhikari NK, Connolly B, Diaz, JV. et al., What is an intensive care unit? A report of the task force of the World Federation of Societies of Intensive and Critical Care Medicine. J. Crit. Care 2017;37:270–276.
Wong H, Curry N, Stanworth SJ. Blood products and procoagulants in traumatic bleeding. Current Opinion in Critical Care. 2016;22(6):598–606.
Ruiz C, Andresen M. Resuscitation with fluids and blood products in trauma. Revista médica de Chile. 2014;142(6):758–766.
Yuliarto S, Kadafi KT, Azizah LN, Susanto WP, Khalasha T. Impact of restrictive versus liberal transfusion and clinical outcomes in critically ill children: A retrospective observational study. Health Science Reports. 2022;5(6).
Okoroiwu HU, Okafor IM. Demographic characteristics of blood and blood components transfusion recipients and pattern of blood utilization in a tertiary health institution in southern Nigeria. BMC Hematol. 2018;18(16).
Al-Faris L, Al-Fares AR, Abdul Malek K, Omran A, Al-Humood S. Blood transfusion practice in critically ill patients: a single institutional experience. Med. Princ. Pract. 2012;21(6):560–565.
Raghuwanshi B, Pehlajani NK, Sinha MK, Tripathy S. A retrospective study of transfusion practices in a tertiary care institute. Indian J. Anaesth. 2017;61(1):24-28.
Kementerian Kesehatan Republik Indonesia. INFODATIN Pusat Data dan Informasi Kementerian Kesehatan RI Pelayanan Darah Di Indonesia. 2018
Directorate General of Population and Civil Registration Ministry of Internal Afffairs. Indonesia miliki bank data 37,9 juta golongan darah. Jakarta:2021. ï›cited 2022 Dec 16ï”. Available from https://dukcapil.kemendagri.go.id/berita/baca/725/dirjen-dukcapil-indonesia-miliki-bank-data-379-juta-golongan-darah
Sharma A, Singh V, Alavi A. Epidemiology and predictors of blood transfusion in hospitalizations for sickle cell disease. Blood. 2021;138(1):3103.
Akbas T. Long length of stay in the ICU associated with a high erythrocyte transfusion rate in critically ill patients. J. Int. Med. Res. 2019;47(5):1948–1957.
Tobi KU, Imarengiaye CO. Blood transfusion in critically ill patients in an intensive care unit of a tertiary hospital in Nigeria. East Afr. Med. J. 2014;91(12):1-7.
Kaushansky K, Lichtman MA, Prchal JT, Levi MM, Press OW, Burns LJ. et al., Williams Hematology. 9th ed. New York: McGraw-Hill Education; 2016.
Doku, George N, Agbozo WK, Annor RA, Mawudzro PE, Agbeli EE. et al., Frequencies and ethnic distribution of ABO and RhD blood groups in the Volta region of Ghana, towards effective blood bank services. Afr. Health Sci. 2022;22(1):641–7.
Kipkulei JC, Buziba N, Mining S, Jepngetich H. Demographic and Clinical Profiles of Blood Transfusion Recipients at a Teaching and Referral Hospital in Kenya. Open J. Blood Dis. 2019;9(1):30–40.
Squires JE. Indications for platelet transfusion in patients with thrombocytopenia. Blood Transfusion. 2015;13(2):221-226.
Klein AA, Arnold P, Bingham RM, Brohi K, Clark R., et al., AAGBI guidelines: the use of blood components and their alternatives 2016. Anaesthesia. 2016;71(7):829-842.
Unal D, Senayli Y, Polat R, Spahn DR, Toraman F, Alkis N., et al., Peri-operative blood transfusion in elective major surgery: incidence, indications, and outcome – a multicentre observational study. Blood Transfus. 2020;4(18):261-279.
Wahidiyat PA, Marpaung E, Iskandar SD. Characteristics of Acute Transfusion Reactions and its related factors in Cipto Mangunkusumo Hospital Jakarta, Indonesia. Heal. Sci. J. Indones. 2019;10(1):15–20.
Mafirakureva N, Khoza S, Hassall O, Faragher BE, Kajja I, Mvere DA. et al., Profiles of blood and blood component transfusion recipients in Zimbabwe. Blood Transfus. 2015;4(13):600–609.
Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee. Transfusion Handbook. 2014. ï›cited 2022 December 16 ï”. Available from https://www.transfusionguidelines.org/transfusion-handbook/4-safe-transfusion-right-blood-right-patient-right-time-and-right-place/4-13-transfusion-of-blood-components
Trompeter S, Cohen A, Porter J. Guidelines for the Management of Transfusion Dependent Thalassaemia (TDT). 3rd ed. Nicosia: Thalassemia International Federation; 2014
Maulydia M, Airlangga PS, Siregar MI, Hendriana DR. Transfusion-related acute lung injury (TRALI) in postpartum bleeding patient: A case report. Bali J Anaesthesiol 2022;6:119-122.
Copyright (c) 2023 Almira Saskia Sabila, Maulydia, Betty Agustina Tambunan, Edward Kusuma
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Indonesian Journal of Anesthesiology and Reanimation (IJAR) licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
1. Copyright holder is the author.
2. The journal allows the author to share (copy and redistribute) and adapt (remix, transform, and build) upon the works under license without restrictions.
3. The journal allows the author to retain publishing rights without restrictions.
4. The changed works must be available under the same, similar, or compatible license as the original.
5. The journal is not responsible for copyright violations against the requirement as mentioned above.