Anesthesia and Surgical Considerations in Awake Craniotomy for Eloquent Area Tumor
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Introduction: Awake craniotomy is a specialized neurosurgical technique in which the patient remains conscious during surgery, enabling real-time functional mapping of the cerebral cortex. This procedure is primarily employed when a brain tumor or lesion is situated near critical areas responsible for motor, visual, or language functions. Its application minimizes the risk of postoperative neurological deficits, ensuring the preservation of vital brain functions.
Objective: The objective of this case report is to highlight the use of the awake craniotomy technique for a patient with a brain tumor located in the left parietal lobe, emphasizing the surgical and anesthetic considerations necessary for successful outcomes.
Case Report: The patient, diagnosed with a brain tumor in the left parietal lobe, presented unique surgical challenges due to the tumor's proximity to the cortical centers governing movement and speech. To mitigate the risk of neurological impairment, an awake craniotomy was performed. Bilateral scalp nerve blocks were administered for effective pain management, alongside dexmedetomidine to provide conscious sedation. The "awake-wake-wake" protocol was followed, ensuring the patient remained alert throughout critical phases of the surgery. This allowed the surgical team to conduct real-time assessments of motor and language functions, optimizing tumor resection while preserving neurological integrity.
Conclusion: This case underscores the importance of the awake craniotomy technique in neurosurgical interventions involving eloquent brain regions. The use of dexmedetomidine and precise nerve blocks provided effective sedation and analgesia, enabling active patient participation during functional mapping. The procedure highlights the value of interdisciplinary collaboration between neurosurgeons and anesthesiologists to achieve optimal patient outcomes while minimizing neurological risks.
Stevanovic A, Rossaint R, Veldeman M, Bilotta F, Coburn M. Anaesthesia management for awake craniotomy: systematic review and meta-analysis. PLoS One. 2016; 11(5): e0156448.
Kim SH, Choi SH. Anesthetic considerations for awake craniotomy. Anesth Pain Med. 2020; 15(3): 269-74.
Cottrell JE, Patel P. Cottrell and Patel’s Neuroanesthesia E-Book: Elsevier Health Sciences; 2016.
Goettel N, Bharadwaj S, Venkatraghavan L, Mehta J, Bernstein M, Manninen PH. Dexmedetomidine vs propofol-remifentanil conscious sedation for awake craniotomy: a prospective randomized controlled trial. BJA: British Journal of Anaesthesia. 2016; 116(6): 811-21.
Soehle M, Wolf CF, Priston MJ, Neuloh G, Bien CG, Hoeft A, et al. Propofol Pharmacodynamics and Bispectral Index During Key Moments of Awake Craniotomy. J Neurosurg Anesthesiol. 2018; 30(1): 32-8.
Prontera A, Baroni S, Marudi A, Valzania F, Feletti A, Benuzzi F, et al. Awake craniotomy anesthetic management using dexmedetomidine, propofol, and remifentanil. Drug Design, Development and Therapy. 2017: 593-8.
Brosnan H, McLean M, Abramowicz AE. Anesthetic Selection for an Awake Craniotomy for a Glioma With Wernicke's Aphasia: A Case Report. Cureus. 2022; 14(3): e23181.
Freitas CH, Oliveira CHS, Rezende DC, Romano J, Silva HRL, Trivellato IM. Anesthetic considerations for awake craniotomy: case report. 2018; 68(3): 311-4.
Bolzani ND, Junqueira Dde O, Ferrari PA, Ferrari AF, Gaia F, Tapajós CM, et al. Anesthesia for awake craniotomy: case report. 2013; 63(6): 500-3.
Madriz-Godoy MM, Trejo-Gallegos SA. Anaesthetic technique during awake craniotomy. Case report and literature review. Revista Médica del Hospital General de México. 2016; 79(3): 155-60.
Copyright (c) 2025 Mehrdad Masoudifar, Maryam Mirhosseini, Amirhossein Najafabadipour

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