Amila Amila, Evarina Sembiring

Abstract views = 1154 times | downloads = 409 times


hemoglobin levels in patients with pulmonary tuberculosis. This study aimed to examine the effect of beetroot biscuits consumption on the increase of hemoglobin levels in patients with pulmonary tuberculosis at the Integrated Service Unit of the Pulmonary Central Hospital of North Sumatera. The research design was quasi experimental  and used pre-tests and post-tests without a control approach. This study was conducted with a sample of 100 patients selected using the purposive sampling technique. Firstly, the hemoglobin level of the patients was measured. Then, beetroot biscuits were given to the patients for thirty days as the intervention. A Wilcoxon test was performed to pinpoint the differences between the pre-test and post-test results. It was found that there was a 2.01 gr/dl increase in hemoglobin after beetroot biscuits were given to patients with pulmonary tuberculosis at the Integrated Service Unit of the Pulmonary Central Hospital of North Sumatera. It was also found that the differences were significant when comparing the average level of hemoglobin before and after the intervention with a p value of 0.000. This study suggests that doctors and nurses play important roles in constructing patients’ knowledge and understanding on the importance of anemia prevention in order to improve community knowledge to use local resources to improve health outcomes.

Keywords: anemia, biscuit, beetroot, tuberculosis


Anemia, Biscuit, Beetroot, Tuberculosis

Full Text:



Adzani, M., Dalimoenthe, N. Z., & Wijaya, I. (2016). Profile of Anemia on Lung Tuberculosis at Dr . Hasan Sadikin General Hospital and Community Lung Health Center Bandung. 3(1), 137–140.

Al-Aboud, N. M. (2018). ISABB Journal Of Food And Agriculture Science Effect of red beetroot (Beta vulgaris L.) intake on the level of some hematological tests in a group of female volunteers. 8(2), 10–17.

Almatsier, & Sunita. (2006). Prinsip Dasar Ilmu Gizi (Fundamental Principles Of Nutrition Sciences). Jakarta: Gramedia Pustaka Utama.

Amin, Z., & Bahar, A. (2009). Ajar IlmuPenyakitDalamJilid II Edisi IV (Teaching M). Jakarta: Interna.

Atamanova, S. A., Brezhneva, T. A., Slivkin, A. I., Nikolaevskii, V. A., Selemenev, V. F., & Mironenko, N. V. (2005). Isolation of saponins from table beetroot and primary evaluation of their pharmacological activity. Pharmaceutical Chemistry Journal, 39(12), 650–652.

Clifford, T., Howatson, G., West, D. J., & Stevenson, E. J. (2015). The potential benefits of red beetroot supplementation in health and disease. Nutrients, 7(4), 2801–2822.

De Azeredo, H. M. C., Pereira, A. C., De Souza, A. C. R., Gouveia, S. T., & Mendes, K. C. B. (2009). Study on efficiency of betacyanin extraction from red beetroots. International Journal of Food Science and Technology, 44(12), 2464–2469.

De Zwart, F. J., Slow, S., Payne, R. J., Lever, M., George, P. M., Gerrard, J. A., & Chambers, S. T. (2003). Glycine betaine and glycine betaine analogues in common foods. Food Chemistry, 83(2), 197–204.

Dias, M. G., Camões, M. F. G. F. C., & Oliveira, L. (2009). Carotenoids in traditional Portuguese fruits and vegetables. Food Chemistry, 113(3), 808–815.

Gilchrist, M., Winyard, P. G., Fulford, J., Anning, C., Shore, A. C., & Benjamin, N. (2014). Nitric Oxide Dietary nitrate supplementation improves reaction time in type 2 diabetes : Development and application of a novel nitrate-depleted beetroot juice placebo. NITRIC OXIDE, 40, 67–74.

Glaziou, P., Floyd, K., & Raviglione, M. C. (2015). Global Epidemiology of Tuberculosis. Cold Spring Harb Perspect Med, 5, 1–18.

Glaziou, P., Sismanidis, C., Floyd, K., & Raviglione, M. (2015). Global Epidemiology of Tuberculosis. 1–17.

Gupta, K. B., Gupta, R., Atreja, A., Verma, M., & Vishvkarma, S. (n.d.). Tuberculosis and nutrition.

Hobbs, D. A., Goulding, M. G., Nguyen, A., Malaver, T., Walker, C. F., George, T. W., … Lovegrove, J. A. (2013). Acute Ingestion of Beetroot Bread Increases Endothelium-Independent Vasodilation and Lowers Diastolic Blood Pressure in Healthy Men: A Randomized Controlled Trial. Journal of Nutrition, 143(9), 1399–1405.

Indumathi, T., & Kannikaparameswari. K. (2014). Internationally indexed journal. Int J Pharm Bio Sci, 5(1), 978–982.

Ingle, M., Ingle, M. P., Thorat, S. S., Nimbalkar, C. A., & Nawkar, R. R. (2017). Nutritional Evaluation of Cookies Enriched with Beetroot ( Beta vulgaris L .) Powder. 6(3), 1888–1896.

Isanaka, S., Mugusi, F., Urassa, W., Willett, W. C., Bosch, R. J., Villamor, E., … Fawzi, W. W. (2012). Iron deficiency and anemia predict mortality in patients with tuberculosis. Journal of Nutrition, 142(2), 350–357.

Jastrebova, J., Wittho, C., Grahn, A., Svensson, U., & Ja, M. (2003). HPLC determination of folates in raw and processed beetroots. 80, 579–588.

Kapadia, G. J., Tokuda, H., Konoshima, T., & Nishino, H. (1996). Chemoprevention of lung and skin cancer by Beta vulgaris (beet) root extract. Cancer Letters, 100(1–2), 211–214.

Karoum, A. O., Mohamed, B. A., Siddig, M. F., & Bari, E. G. (2009). Anemia in Kassala Area Eastern Sudan. Sudan Journal of Medical Sciences, 4(1), 31–35.

Kavalcová, P., Bystrická, J., Tomáš, J., Karovičová, J., Kovarovič, J., & Lenková, M. (2015). The content of total polyphenols and antioxidant activity in red beetroot. Potravinarstvo, 9(1), 77–83.

Indonesian Ministry of Health. (2016). Profil Kesehatan Indonesia. In Profil Kesehatan Provinsi Bali.

Indonesian Ministry of Health. (2013). Riset Kesehatan Dasar. 1–268.

Lopez, A. D., & Mathers, C. D. (2006). Measuring the global burden of disease and epidemiological transitions: 2002-2030. Annals of Tropical Medicine and Parasitology, 100(5–6), 481–499.

Monjur, F., & Rizwan, F. (2014). A Cross-sectional Study of Morphological Types of Anemia in Pulmonary Tuberculosis Patient and Associated Risk Indicators in a Selected Hospital of Dhaka City , Bangladesh. Internation Journal Of Chemical, Environmental & Biological Sciences (IJCEBS), 2(4), 215–219.

Muhammad, A. (2005). Determination of iron deficiency in chronic disease anemia by the role of sTfR-F index. (1), 2005.

Murphy, M., Eliot, K., Heuertz, R., & Weiss, M. (2011). Whole beetroot consumption acutely improves running performance.

Ninfali, P., & Angelino, D. (2013). Fitoterapia Nutritional and functional potential of Beta vulgaris cicla and rubra. Fitoterapia, 89, 188–199.

Oliveira, M. G., Delogo, K. N., Oliveira, H. M. de M. G. de, Ruffino-Netto, A., Kritski, A. L., & Oliveira, M. M. (2014). Anemia in hospitalized patients with pulmonary tuberculosis. Jornal Brasileiro de Pneumologia, 40(4), 403–410.

Pallavi Joshi & Beena Mathur. (2010). Bioavailability of Iron from the Leaf Powders Of Dehydrated Less Utilized Green Leafy Vegetables. Asian J.Exp.Biol.Sci., 1(4), 845–854.

Piso, R. J., Kriz, K., & Desax, M. (2011). Severe isoniazid related sideroblastic anemia. 3, 2–3.

Presley, T. D., Morgan, A. R., Bechtold, E., Clodfelter, W., Dove, R. W., Jennings, J. M., … Miller, G. D. (2011). Nitric Oxide Acute effect of a high nitrate diet on brain perfusion in older adults. Nitric Oxide, 24(1), 34–42.

Priya, N. G., Malarvizhi, M., & Jothi, A. J. (2013). Beet root juice on haemoglobin among adolescent girls. 2(1), 9–13.

Ruditya, D. N. (2015). HUBUNGAN ANTARA KARAKTERISTIK PENDERITA TB DENGAN. Jurnal Berkala Epidemiologi, 3(2), 122–133.

Sei, W. L., Young, A. K., Young, S. Y., Um, S. W., Sang, M. L., Yoo, C. G., … Yim, J. J. (2006a). The prevalence and evolution of anemia associated with tuberculosis. Journal of Korean Medical Science, 21(6), 1028–1032.

Sei, W. L., Young, A. K., Young, S. Y., Um, S. W., Sang, M. L., Yoo, C. G., … Yim, J. J. (2006b). The prevalence and evolution of anemia associated with tuberculosis. Journal of Korean Medical Science, 21(6), 1028–1032.

Shafee, M., Abbas, F., Ashraf, M., Mengal, M. A., Kakar, N., Ahmad, Z., & Ali, F. (2014). Hematological profile and risk factors associated with pulmonary tuberculosis patients in Quetta, Pakistan. Pakistan Journal of Medical Sciences, 30(1), 36–40.

Suryandari, A. E., & Happinasari, O. (2015). Perbandingan Kenaikan Kadar Hb pada Ibu Hamil yang Diberi Fe dengan Fe dan Buah Bit di Wilayah Kerja Puskesmas Purwokerto Selatan. Jurnal Kebidanan, VII(01), 36–47.

Umakanth, M. (2017). Anemia among tuberculosis patient in teaching hospital Batticaloa, Sri Lanka. International Journal of Medical and Health Research, 3(5), 2454–9142.

Umakanth, M., & Rishikesavan, S. (2017). Prevalence of diabetes mellitus among tuberculosis patient in Batticaloa district , Sri Lanka. 2(2), 21–23.

Váli, L., Stefanovits-Bányai, É., Szentmihályi, K., Fébel, H., Sárdi, É., Lugasi, A., … Blázovics, A. (2007). Liver-protecting effects of table beet (Beta vulgaris var. rubra) during ischemia-reperfusion. Nutrition, 23(2), 172–178.

Vanhatalo, A., Bailey, S. J., Blackwell, J. R., DiMenna, F. J., Pavey, T. G., Wilkerson, D. P., … Jones, A. M. (2010). Acute and chronic effects of dietary nitrate supplementation on blood pressure and the physiological responses to moderate-intensity and incremental exercise. American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 299(4), 1121–1131.

WHO. (2014). Global tuberculosis report 2014 WHO Library Cataloguing-in-Publication Data. Who, 1–171.

Wootton-Beard, P. C., Moran, A., & Ryan, L. (2011). Stability of the total antioxidant capacity and total polyphenol content of 23 commercially available vegetable juices before and after in vitro digestion measured by FRAP, DPPH, ABTS and Folin-Ciocalteu methods. Food Research International, 44(1), 217–224.

Wruss, J., Waldenberger, G., Huemer, S., Uygun, P., Lanzerstorfer, P., Müller, U., … Weghuber, J. (2015). Compositional characteristics of commercial beetroot products and beetroot juice prepared from seven beetroot varieties grown in Upper Austria. Journal of Food Composition and Analysis, 42(3), 46–55.


  • There are currently no refbacks.

Copyright (c) 2021 The Indonesian Journal of Public Health

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.



View More Indexing and Abstracting

View My Stats