Journal of Basic Medical Veterinary https://e-journal.unair.ac.id/JBMV <p><strong>Journal of Basic Medical Veterinary (JBMV)</strong> (p-ISSN: <a href="https://portal.issn.org/resource/issn/2302-6820" target="_blank" rel="noopener">2302-6820</a>); (e-ISSN:<a href="https://portal.issn.org/resource/issn/2774-9959" target="_blank" rel="noopener"> 2774-9959</a>) is a national journal published by <strong><a href="http://fkh.unair.ac.id/new/" target="_blank" rel="noopener">Faculty of Veterinary Medicine, Universitas Airlangga</a></strong><strong> </strong>and<strong> </strong><strong><a href="https://drive.google.com/file/d/1iFCPODovvOF2xaI8R5_Pgz7lgFkv1uGl/view?usp=sharing" target="_blank" rel="noopener">Indonesian Veterinary Medical Association (IVMA)</a>. </strong>Journal of Basic Medical Veterinary (JBMV) is published periodically two times a year (June and December) by the Department of Basic Medical Veterinary, Faculty of Veterinary Medicine, Universitas Airlangga. This journal published original articles, review articles, and case reports in English version. T<span lang="EN-IN">he scope of this journal has a broad coverage of relevant topics across veterinary basic medical sciences which includes preclinical and paraclinical disciplines i.e. Anatomy, Physiology, Biochemistry, Pathology, Microbiology, Pharmacology, and Medical Education.</span></p> Universitas Airlangga en-US Journal of Basic Medical Veterinary 2302-6820 <p>Journal of Basic Medical Veterinary (JBMV) by <a href="http://www.unair.ac.id/">Unair</a> is licensed under a <a href="http://creativecommons.org/licenses/by-sa/4.0/">Creative Commons Attribution-ShareAlike 4.0 International License</a>.</p><p>1. The journal allows the author to hold the copyright of the article without restrictions.</p><p>2. The journal allows the author(s) to retain publishing rights without restrictions</p><p>3. The legal formal aspect of journal publication accessibility refers to Creative Commons Attribution Share-Alike (CC BY-SA).</p><p>4. The Creative Commons Attribution Share-Alike (CC BY-SA) license allows re-distribution and re-use of a licensed work on the conditions that the creator is appropriately credited and that any derivative work is made available under "the same, similar or a compatible license”. Other than the conditions mentioned above, the editorial board is not responsible for copyright violation.</p><div id="gtx-trans" style="position: absolute; left: -13px; top: 21.4883px;"> </div> Front Cover, Editorial Board, Peer Reviewers, Acknowledgments https://e-journal.unair.ac.id/JBMV/article/view/65973 Salma Aisyafalah, S.Si Copyright (c) 2024 Salma Aisyafalah, S.Si http://creativecommons.org/licenses/by-sa/4.0 2024-12-01 2024-12-01 13 2 Monkey Pox Symptom Identification, Cause, Treatment and Infection Control Prevention https://e-journal.unair.ac.id/JBMV/article/view/64334 <p>Monkey pox is a zoonotic disease that is re-emerging and proliferating in areas where it has not been observed for decades. Monkey pox outbreaks have been documented periodically in the past. Significant outbreaks occurred in Nigeria during 2017-2018, as well as in the United States and Nigeria. The research method used was a literature evaluation, specifically covering literature collected from multiple sources relating to monkey pox disease. Monkey pox is caused by the monkey pox virus. The disease is endemic in Central and West Africa. Human cases have recently spread to additional locations. No cases of monkey pox have been reported in Indonesia. Monkey pox in humans has similarities to smallpox; however, the symptoms are usually less severe. The monkey pox virus is present in skin lesions and in throat and nasopharyngeal swabs. Monkey pox is self-limiting. Treatment is palliative. Transmission of the disease can be reduced by avoiding direct contact with wild animals. In conclusion, monkey pox is a zoonotic disease caused by the monkey pox virus. The disease is self-limiting. The treatment given is symptomatic. The recommended method to prevent transmission is to avoid contact with sick individuals or animals.</p> Vicia Dara Wandira Rifki Adrian Syach Copyright (c) 2024 Vicia Dara Wandira, Rifki Adrian Syach http://creativecommons.org/licenses/by-sa/4.0 2024-12-01 2024-12-01 13 2 94 101 10.20473/jbmv.v13i2.64334 Analysis of EM4 Probiotics Added in The Water on The Hematological Profile of Tilapia (Oreochromis niloticus) https://e-journal.unair.ac.id/JBMV/article/view/53038 <p>This journal reviews the effect of giving EM4 probiotics on the hematological profile of tilapia. This study aims to determine the effects that will arise after administering EM4 probiotics for several days on the blood of tilapia fish. This research uses experimental methods so that the results used are the results of experiments carried out by the author. The results of this study explain the blood profile of tilapia after administration of EM4 probiotics including levels of erythrocytes, leukocytes, hematocrit, hemoglobin and differential counting. There was a decrease in erythrocyte, hemoglobin, hematocrit levels, and an insignificant increase in leukocyte and hematocrit levels.</p> Khansa Nur Faizah Naufal Dzaky Fayyadhafif Nabila Shafia Muhammad Izzudin Azmi Tsabitah Shabrina Nabilah Dzakirah Muhammad Shahruriza Rakai Mahandaru Laily Nur Anggraini Annisa Yuwan Ramadhani Copyright (c) 2024 Khansa Nur Faizah, Naufal Dzaky Fayyadhafif, Nabila Shafia, Muhammad Izzudin Azmi, Tsabitah Shabrina, Nabilah Dzakirah, Muhammad Shahruriza Rakai Mahandaru, Laily Nur Anggraini, Annisa Yuwan Ramadhani http://creativecommons.org/licenses/by-sa/4.0 2024-12-01 2024-12-01 13 2 49 54 10.20473/jbmv.v13i2.53038 Occurrence of Anaplasma sp. infection in pigs (Sus scrofa) at Morgan Farm, Palangka Raya City https://e-journal.unair.ac.id/JBMV/article/view/56944 <p>This research was conducted to identify the occurrence of <em>Anaplasma</em> sp. infection in pigs (<em>Sus scrofa</em>) at Morgan Farm, Pahandut Subdistrict, Palangka Raya City. Palangka Raya City is one of the cities that has great potential to develop pig livestock, but the shortcomings of the farms in Palangka Raya City still apply traditional housing with poor cage sanitation. Samples in this study were obtained from Morgan Farm with a total of 68 pig blood samples, then examined at the Animal Health and Veterinary Public Health Laboratory of Palangka Raya City, then starting with the preparation of PBS solution and making blood review preparations using 10% Giemsa staining. The blood obtained was then reviewed using object glass, absolute methanol, and stained with Giemsa 10%. Identification was carried out using a trinocular microscope with a magnification of 400x and immersion oil was dripped on the object glass. The results of this research showed that 29 pig blood samples were positive out of 68 pig samples, with an occurrence rate of 42.6%. The morphology of <em>Anaplasma</em> sp. found is that there is a round, purplish-blue dot shape at the edge of red blood cells. From these results it can be concluded that the infection of <em>Anaplasma</em> sp. in pigs (<em>Sus scrofa</em>) at Morgan Farm, Pahandut District, Palangka Raya City is 42.6%, which means that the infection is very high for Palangka Raya City.</p> Fierdausi Nur’Aini Febriyatin Boedi Setiawan Wiwik Misaco Yuniarti Prima Ayu Wibawati Aditya Yudhana Copyright (c) 2024 Fierdausi Nur’Aini Febriyatin, Boedi Setiawan, Wiwik Misaco Yuniarti, Prima Ayu Wibawati, Aditya Yudhana http://creativecommons.org/licenses/by-sa/4.0 2024-12-01 2024-12-01 13 2 55 61 10.20473/jbmv.v13i2.56944 The Effectiveness Of Red Power Injection On The Hematological Profile Of Layer Chicken (Gallus domesticus) https://e-journal.unair.ac.id/JBMV/article/view/53106 <p>Layer chickens are one of the most popular types of mass-produced laying hens in Indonesia. One way to keep laying hens healthy is to fulfill their micronutrient and vitamin needs. Giving vitamins such as Red power injection is very good for broilers, layers and fighters. Red power injection contains extra liver which contains vitamin B12, folic acid, and iron which are useful for maintaining chicken health. In this study, researchers wanted to test the effectiveness of Red power injection supplements in increasing blood in laying hens (<em>Gallus domesticus</em>). The study used an experimental research method using two treatments for one day. Four laying hens (<em>Gallus domesticus</em>) that have been provided are divided into two treatment groups with a dose of group one 0.8 ml / head and a dose of group two 1.2 ml / head. The variable observed was the increase of Hematology Profile (Erythrocytes, Leukocytes, and Hemoglobin). The results showed an increase in the Hematology Profile tested. The increase in the Hematology Profile is due to the effect of nutrition on chickens has been fulfilled, Red power injection is a supplement containing liver extract which helps the formation of Hematology Profile in Laying Hens (<em>Gallus domesticus</em>).</p> Rahamaddanu Surya Lazwari Anandira Dania Yasmin Fatun Latifa Lutfiah Zarkasya Zahra Nur Saffanah Fahmi Zatya Dimas Prakoso Nugroho Gogod Wahyu Dewa Easter Palma Dewi Eros Azzahra Shafa Fadhila Fadhila Copyright (c) 2024 Rahamaddanu Surya Lazwari, Anandira Dania Yasmin, Fatun Latifa Lutfiah, Zarkasya Zahra Nur Saffanah Fahmi, Zatya Dimas Prakoso Nugroho, Gogod Wahyu Dewa, Easter Palma Dewi Eros, Azzahra Shafa Fadhila Fadhila http://creativecommons.org/licenses/by-sa/4.0 2024-12-01 2024-12-01 13 2 62 67 10.20473/jbmv.v13i2.53106 Effectiveness of Bay Leaf Extract (Syzygium polyanthum) on Uric Acid and Cholesterol Levels in Caffeine-Induced Male Mice (Mus musculus) https://e-journal.unair.ac.id/JBMV/article/view/65971 <p>Bay leaf (<em>Syzygium polyanthum</em>) is one of the plants from Indonesia that has the potential to be used as a raw material for herbal medicine. Pharmacologically, bay leaves containing flavonoids have been shown to have antioxidant activity, which can reduce hyperuricemia and blood cholesterol levels. This study aims to determine the effectiveness of bay leaf extract in reducing uric acid and cholesterol levels in the blood of mice induced by caffeine. The mice tested animals were divided into six groups, namely a positive control group of uric acid, a positive control of cholesterol, where a positive control of uric acid was given allopurinol and a positive control of cholesterol was given simvastatin, a negative control was given Na-CMC 1%, and a group that was given bay leaf extract in different dose levels, namely P1 was given 20 mg/kg BB, P2 was given 40 mg/kg BB, and P3 was given 80 mg/kg BB. The parameters used were the decrease in blood uric acid and cholesterol levels caused after the treatment was measured using a POCT strip test for uric acid and cholesterol. The data obtained were statistically processed using the One-Way Anova test. The results of the Anova test showed a significant difference (p&lt;0.05) in the data on uric acid and cholesterol levels. Then continued with the results of Duncan's test to see the most effective dose level for bay leaf extract in reducing uric acid and cholesterol levels. In Duncan's test results, it was found that the P3 group of mice with a dose of 80 mg/kg BB was the most effective dose level in reducing uric acid and cholesterol levels in the blood of mice induced by caffeine.</p> Fahrul Andika Pratama Salma Aisyafalah Rochmah Kurnijasanti Copyright (c) 2024 Fahrul Andika Pratama, Salma Aisyafalah, Rochmah Kurnijasanti http://creativecommons.org/licenses/by-sa/4.0 2024-12-01 2024-12-01 13 2 68 80 10.20473/jbmv.v13i2.65971 Role of Vitamin D and E as Antioxidants Against Cerebral Endothelial Dysfunction: An In Vivo Study in White Rats (Rattus norvegicus) Sepsis Model https://e-journal.unair.ac.id/JBMV/article/view/61610 <p>Sepsis is a life-threatening condition caused by the body's response to an infection, leading to organ dysfunction. A antioxidants can help neutralize harmful free radicals that cause cellular and tissue damage through oxidative stress. Vitamin D and E are two antioxidants that have been extensively studied for their potential effectiveness. This study aims to evaluate the effectiveness of vitamins D and E in reducing oxidative stress in the cerebral vascular endothelial cells of Wistar mice in a sepsis model. The study follows an experimental design and uses a posttest with a control group. The levels of NO and SOD in 24 sepsis model mice were measured using ELISA, and the cerebral endothelial tissues were examined histopathologically. An ANOVA test was performed, followed by the Post Hoc LSD test. NO and SOD levels decreased in sepsis rats from 66.88 ± 16.59 to 88.77 ± 12.83µmol/L. Sepsis mice given vitamin D and E showed significant results on changes in NO and SOD levels (p&lt;0.05). Based on the histopathological results of necrosis, inflammation, and hemorrhagic cell damage in sepsis rats reached over 50% of the field of view, significantly different from sepsis mice that had been given vitamin D and E. Sepsis mice were given vitamin D and E influenced 96.2% and 98.7% on changes in NO, SOD, and cerebral endothelial dysfunction (p&lt;0.05). These findings imply that vitamins D and E may be beneficial in managing sepsis-induced cerebral endothelial dysfunction, potentially impacting the treatment and outcomes of sepsis patients.</p> Fauzan Fajri Sukmawan Fajar Denny Irmawati Hasan Herlina Dimiati Eka Yunita Amna Nora Sovira Anidar Anidar Mulya Safri Aris Gunawan Copyright (c) 2024 Fauzan Fajri, Sukmawan Fajar, Denny Irmawati Hasan, Herlina Dimiati, Eka Yunita Amna, Nora Sovira, Anidar Anidar, Mulya Safri, Aris Gunawan http://creativecommons.org/licenses/by-sa/4.0 2024-12-01 2024-12-01 13 2 81 93 10.20473/jbmv.v13i2.61610 Indexing, Subscribed Form, Guidelines for Author, Back Cover https://e-journal.unair.ac.id/JBMV/article/view/65974 Salma Aisyafalah, S.Si Copyright (c) 2024 Salma Aisyafalah, S.Si http://creativecommons.org/licenses/by-sa/4.0 2024-12-01 2024-12-01 13 2