https://e-journal.unair.ac.id/JFIKI <table cellspacing="0" cellpadding="0" align="left"> <tbody> <tr> <td align="left" valign="top"> <p><a href="https://portal.issn.org/resource/ISSN/2580-8303">ISSN International Centre</a> | <a href="https://issn.brin.go.id/terbit/detail/1412835086" target="_blank" rel="noopener">ISSN: 2406-9388 (Print)</a> | <a href="https://issn.brin.go.id/terbit/detail/1468378589" target="_blank" rel="noopener">ISSN: 2580-8303 (Online)</a></p> <p>Jurnal Farmasi dan Ilmu Kefarmasian Indonesia (Pharmacy and Pharmaceutical Sciences Journal) P-ISSN: 2406-9388; E-ISSN: 2580-8303 is an official journal published by the Faculty of Pharmacy, Universitas Airlangga in collaboration with <a href="https://iaijatim.id/">Indonesian Pharmacists Association (IAI) of East Java</a> and <a href="https://www.centerforpatientsafety-indonesia.com/">Center for Patient Safety Research</a> which the articles can be accessed and downloaded online by the public (open access journal).</p> <p>This journal is a peer-reviewed journal published three times a year on topics of excellence of research results in the fields of service and practice of pharmacy, community medicine, pharmaceutical technology, and health science disciplines that are closely related. This journal accepts English texts. The following are the research areas that this journal focuses on</p> <p>1. Clinical Pharmacy<br />2. Community Pharmacy<br /><span style="font-size: 0.875rem;">3. Pharmaceutics<br /></span><span style="font-size: 0.875rem;">4. Pharmaceutical Chemistry<br /></span><span style="font-size: 0.875rem;">5. Pharmacognosy<br /></span><span style="font-size: 0.875rem;">6. Phytochemistry</span></p> <p>Jurnal Farmasi dan Ilmu Kefarmasian Indonesia (Pharmacy and Pharmaceutical Sciences Journal) receives manuscript from the results of research (research article), systematic reviews and meta analysis that are closely related to the health sector, particularly the pharmaceutical field. Selected manuscripts for publication in this journal will be sent to two reviewers expert in their field, who are not affiliated with the same institution as the author(s), and are chosen based on the consideration of the editorial team. The review process is conducted in a closed manner where the author(s) and reviewers do not know the identity and affiliation of each. Each manuscript delegated to editorial members is examined for the final decision of the review process. The author(s) are required to respond to the review given and send revised manuscripts within the allotted time after the comments and suggestions from the reviewers have been sent. Manuscripts accepted for publication are edited copies checked for the grammar, punctuation, print style, and format. The entire process of submitting the manuscripts to the final decision for publishing is done online. </p> <p>JFIKI has been indexed in <a href="https://doaj.org/toc/2580-8303?source=%7B%22query%22%3A%7B%22bool%22%3A%7B%22must%22%3A%5B%7B%22terms%22%3A%7B%22index.issn.exact%22%3A%5B%222406-9388%22%2C%222580-8303%22%5D%7D%7D%5D%7D%7D%2C%22size%22%3A100%2C%22sort%22%3A%5B%7B%22created_date%22%3A%7B%22order%22%3A%22desc%22%7D%7D%5D%2C%22_source%22%3A%7B%7D%2C%22track_total_hits%22%3Atrue%7D" target="_blank" rel="noopener">DOAJ</a>, <a href="https://sinta.kemdikbud.go.id/journals/profile/5280" target="_blank" rel="noopener">Sinta 2</a>, <a href="https://app.dimensions.ai/discover/publication?search_mode=content&amp;search_text=Jurnal%20Farmasi%20dan%20Ilmu%20Kefarmasian%20Indonesia&amp;search_type=kws&amp;search_field=full_search&amp;or_facet_source_title=jour.1301095" target="_blank" rel="noopener">Dimensions</a>, <a href="https://essentials.ebsco.com/search/eds/details/jurnal-farmasi-dan-ilmu-kefarmasian-indonesia?query=Jurnal%20Farmasi%20Dan%20Ilmu%20Kefarmasian%20Indonesia&amp;requestCount=0&amp;db=edsdoj&amp;an=edsdoj.28ff8dd490e84b75b8645da7e506f18d">EBSCO</a>, and <a href="https://e-journal.unair.ac.id/JFIKI/Editorial_Policies#custom-2" target="_blank" rel="noopener">others indexing</a>. This journal has been accredited as a 2nd Grade Scientific Journal (Sinta 2) by the Ministry of Research, Technology, and Higher Education of Indonesia since 23 December 2020.</p> </td> </tr> </tbody> </table> Universitas Airlangga en-US JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA 2406-9388 <p>1. The copyright of this journal belongs to the Editorial Board and Journal Manager with the author's knowledge, while the moral right of the publication belong to the author.</p><p>2. The formal legal aspect of journal publication accessibility refers to the Creative Commons Attribution-Non-Commercial-Share Alike (CC BY-NC-SA), which implies that the publication can be used for non-commercial purposes in its original form.</p><p>3. Every publication (print/electronic) is open access for educational, research, and library purposes. In addition to the objectives mentioned above, the editorial board is not responsible for copyright infringement</p><span class="tlid-translation translation" lang="id"><span title=""><br /></span></span> https://e-journal.unair.ac.id/JFIKI/article/view/57818 <p><strong><em>Background</em></strong><em>: Randu honey is monofloral honey sourced from one type plant nectar. The geographical location of randu (</em>Ceiba pentandra<em>) as the source of nectar is one factor that influences antimicrobial activity produced by randu honey. This research used randu honey from several regions in Java such as Sidoarjo (RSH), Pusat Perlebahan Nasional Bogor (RBH), Kediri (RKH), and Malang (RMH).<strong> Objective</strong>: To compare the antimicrobial activity of several randu honeys (RSH,RBH,RKH,RMH) against Gram-negative </em>Escherichia coli<em> ATCC 25922, Gram-positive </em>Staphylococcus aureus<em> ATCC 6538 and methicillin-resistant </em>Staphylococcus aureus<em> (MRSA) ATCC 33592, </em>Candida albicans<em> ATCC 10231.<strong> Methods</strong>: This study used well diffusion and dilution antimicrobial test methods. The diameter of inhibition zone formed in well diffusion method is measured using a vernier caliper. The diffusion method was used as screening test before determining quantitative minimum inhibitory concentration (MIC) using serial dilution with a ratio1:2 (v/v). Streptomycin and Ketoconazole were used as positive controls. Nutrient broth and Sabouraud broth media were incubated at 37°C for 24 hours (antibacterial tests) and 25°C for 48 hours (antifungal test) respectively.<strong> Results</strong>: Well diffusion test revealed all randu honey samples could inhibit test bacteria and fungi with the appearance of an inhibition zone. Diameter inhibition zone ranged from 14.66±0.52mm to 27.86±0.43mm. The MICs of RSH,RBH,RKH,RMH ranged from 3.12% to 25% against all test bacteria and fungi.<strong> Conclusion</strong>: The results of this study showed randu honey from Bogor (RBH) has the highest antimicrobial activity based on diffusion and dilution tests.</em></p> Nindya Pramesti Wardani Riesta Primaharinastiti Achmad Toto Poernomo Copyright (c) 2024 JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA http://creativecommons.org/licenses/by-nc-sa/4.0 2024-08-06 2024-08-06 https://e-journal.unair.ac.id/JFIKI/article/view/57734 <p><strong><em>Background:</em></strong><em> The success of making nanoemulsions with the aim of producing good characteristic values is determined by the ratio of each component. The Design of Experimental (DoE) approach using the Simplex Lattice Design (SLD) method can be used to determine the optimal formula for nanoemulsion, with variable factors consisting of oleic acid, Tween 20:ethanol (4:1), and water. The response variables observed included droplet size, PDI, and pH. <strong>Objective</strong>: DoE can help reduce energy, costs, and time needed to make the optimal formula of diclofenac sodium nanoemulsion. <strong>Methods</strong>: Nanoemulsions were prepared using a low-energy emulsification method. Their characteristics were evaluated and analyzed with Design Expert software. <strong>Result</strong>: The optimal nanoemulsion formulation consists of 4.17% oleic acid, 37.5% emulsifier (Tween 20 : ethanol 4:1), and 58.33% water. The results of nanoemulsion characteristics were good, with 20.37 nm droplet size, 0.42 PDI, and 4.75 pH. The observed values were not significantly different from the predicted values, and the formula could trap 1% diclofenac sodium well. <strong>Conclusion</strong>: The simplex lattice design method is very useful in pharmaceutical development, such as nanoemulsion optimization.</em></p> Nadhifatun Nahdhia M. Agus Syamsur Rijal Esti Hendradi Riyanto Teguh Widodo Copyright (c) 2024 JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA http://creativecommons.org/licenses/by-nc-sa/4.0 2024-08-06 2024-08-06