Family Support is the Key to Compliance with the Treatment of Relapsing Schizophrenia Patients

Betie Febriana, Wigyo Susanto, Dwi Heppy Rochmawati, Wahyu Endang Setiawati

Abstract views = 304 times | downloads = 283 times


Introduction: One problem in treating schizophrenia patients is relapse. The previous study results state that the biggest factor causing relapse is non-compliance with taking medication. This non-compliance with taking medication is influenced by several factors, including patient sociodemography, drug side effects, and family support. The purpose of this study was to determine the factors associated with medication adherence in Schizophrenia patients who were undergoing rehospitalization in an inpatient installation at RSJD in one city in Central Java, Indonesia.

Methods: This study is a descriptive correlational analytic study with a cross-sectional approach. The population in this study were Schizophrenia patients who were undergoing re-hospital in the inpatient installation. Thirty-six samples were taken with the consecutive sampling method. The research instruments used were a socio-demographic questionnaire, family support questionnaire, Medication Adherence Rating Scale (MARS), and Glasgow Antipsychotic Side-effect Scale (GASS). Data analysis using descriptive analysis and chi-square test.

Results: There is a relationship between family support for relapse in schizophrenia patients (p = 0.023).

Conclusion: Researchers suggest that the hospital improves the treatment of family motivation to provide good support to patients to reduce the rate of re-hospitalization.


medication adherence; re-hospitalization; schizophrenia

Full Text:



Alphs, L., Nasrallah, H. A., Bossie, C. A., Fu, D.-J., Gopal, S., Hough, D., & Turkoz, I. (2016). Factors associated with relapse in schizophrenia despite adherence to long-acting injectable antipsychotic therapy. International Clinical Psychopharmacology, 31(4).

Chabungbam, G., Avasthi, A., & Sharan, P. (2007). Sociodemographic and clinical factors associated with relapse in schizophrenia: Factors affecting schizophrenic relapse. Psychiatry and Clinical Neurosciences, 61(6), 587–593.

Chakrabarti, S. (2011). S. Family interventions in schizophrenia: Issues of relevance for Asian countries. World Journal of Psychiatry, 1(1), 4.

Christiawati. (2012). Hubungan cara bayar, jarak tempat tinggal, dan dukungan Keluarga dengan Kepatuhan berobat rawat jalan pasien skizofrenia di RSJD Surakarta. Universitas Muhammadiyah Surakarta.

Christy, C. (2011, May). Relapse in Schizophrenia. The Hongkong Medical Gallery, 16(5), 9.

Dewi, S., Elvira, S., & Budiman, R. (2013). Gambaran kebutuhan hidup penyandang skizofrenia. Jurnal Indonesi MEdical Associacion, 63(3), 84–90.

Eack M. (2007). Quality of life for persons living with schizophrenia: More than just symptoms. Psychiatric Rehabilitation Journal, 30(3), 219.

Fadli, & Mitra. (n.d.). Pengetahuan dan Ekspresi Emosi Keluarga serta Frekuensi Kekambuhan Penderita Skizofrenia. Kesmas: National Public Health Journal, 7(10), 466.

Habibi, R., Nayer, M., & Zadeh, M. (2015). Educational Needs of Families of Patients with Schizophrenia: A Literature Review. International Journal of Medical Reviews, 2(2), 250–255.

Hui, C., Chiu, C., Li, Y.-K., Law, C., Chang, W. C., Chan, S., Lee, E., Sham, P., & Chen, E. (2015). The Effect of Paternal Age on Relapse in First-Episode Schizophrenia. Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie, 60, 346–353.

Jalil, M. (2006). Faktor-faktor yang mempengaruhi kekambuhan penderita skizofrenia di RSJ Prof Dr. Soeroyo Magelang.

Jeong, H.-G., & Lee, M.-S. (2013). Long-acting Injectable Antipsychotics in First-episode Schizophrenia. Clinical Psychopharmacology and Neuroscience, 11.

Kazadi, N., Moosa, M., & Jeenah, F. (2008). Factors associated with relapse in schizophrenia. S Afr J Psychiatry, 14.

Kementrian Kesehatan RI. (2018). Riset kesehatan dasar 2018. Kementrian Kesehatan.

Khankeh, H., Rahgozar, M., & Ranjbar, M. (2011). The effects of nursing discharge plan (post-discharge education and follow-up) on self-care ability in patients with chronic schizophrenia hospitalized in Razi psychiatric Center. Iranian Journal of Nursing and Midwifery Research., 16(2), 162.

Koujalgi, S., & Shobhadevi, R. (2013). Family burden in patient with schizophrenia and depressive disorder: A comparative study. Indian Journal of Psychological Medicine., 35(3), 251.

Lee, S.-U., Soh, M., Ryu, V., Kim, C.-E., Park, S., Roh, S., Oh, I.-H., Lee, H.-Y., & Choi, S. (2018). Risk factors for relapse in patients with first-episode schizophrenia: Analysis of the Health Insurance Review and Assessment Service data from 2011 to 2015. International Journal of Mental Health Systems, 12(1), 9.

Nadeem, B. M. (2013). Attitude of schizophrenic patients’ care givers about their method of patient caring at home. Holistic Nursing And Midwifery Journal, 23(1), 54–62.

Panayiotopoulos, C., Pavlakis, A., & Apostolou, M. (2013). Family burden of schizophrenic patients and the welfare system; the case of Cyprus. Int J Ment Health Syst., 7(1), 13.

Porcelli, S., Bianchini, O., De Girolamo, G., Aguglia, E., Crea, L., & Serretti, A. (2016). Clinical factors related to schizophrenia relapse. International Journal of Psychiatry in Clinical Practice, 20(2), 54–69.

Pratama, Syahrial, & Ishak. (2015). Hubungan keluarga pasien terhadap kekambuhan Skizofrenia di BLUD RSJ Aceh. Jurnal Kedokteran Syiah Kuala, 15(2).

Riba, M., Sharfstein, S., & Tasman, A. (2005). The American Psychiatric Association. International Psychiatry, 2, 18–20.

Rohan, J. M., Huang, B., Pendley, J. S., Delamater, A., Dolan, L., Reeves, G., & Drotar, D. (2015). Predicting health resilience in pediatric type 1 diabetes: A test of the resilience model framework. Journal of Pediatric Psychology, 40(9), 956–967.

Ryandini, Saraswati, & Meikawati. (2011). Faktor-faktor yang berhubungan Dengan Kekambuhan pada pasien skizofrenia di Rumah Sakit Jiwa Daerah Dr. Amino Gondohutomo Semarang. Jurnal Keperawatan Dan Kebidanan. STIKKES Telogorejo Semarang, 1(4), 211–215.

Sadock, B., & Sadock, V. (2010). Kaplan & sadock’s synopsis of psychiatry: Behavioral sciences/clinical psychiatry. (10th ed.). Lippincott Williams & Wilkins.

Sariah, A. E., Outwater, A. H., & Malima, K. I. Y. (2014). Risk and protective factors for relapse among individuals with schizophrenia: A qualitative study in Dar es Salaam, Tanzania. BMC Psychiatry, 14, 240–240. PubMed.

Sharif, F., Shaygan, M., & Mani, A. (2012). Effect of a psycho-educational intervention for family members on caregiver burdens and psychiatric symptoms in patients with schizophrenia in Shiraz, Iran. BMC Psychiatry, 12(1), 48.

Simanullang, R. H. (2018). The Correlation Between Family Support And Relapse In Schizophrenia At The Psychiatric Hospital. Belitung Nursing Journal; Vol 4, No 6 (2018): November-December 2018DO - 10.33546/Bnj.389.

Stuart, G. W. (2014). Principles and Practice of Psychiatric Nursing—E-Book. Elsevier Health Sciences.

WHO. (2016). Schizophrenia. health schizophrenia/en/2016

World Federation Of Mental Health. (2008). Learning About Schizophrenia: An international Mental Health awareness packet. Http://www.

Yildirim, A. (2014). The Effect of Family-to-Family Support Programs Provided for Families of Schizophrenic Patients on Information about Illness, Family Burden and Self-Efficacy. Turkish Journal of Psychiatry., 25(1).

Zahnia, S., & Sumekar, D. W. (n.d.). Kajian Epidemiologis Skizofrenia. 7.


  • There are currently no refbacks.

Copyright (c) 2020 Jurnal Ners

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

This journal is indexed by:





This journal is published by:


          Faculty of Nursing Universitas Airlangga in Collaboration with Indonesian National Nurses Association


Creative Commons License

This journal (p-ISSN:1858-3598; e-ISSN:2502-5791) is licensed under a Creative Commons Attribution 4.0 International License


Current Stats

Previous Stats