Modern and Convensional Wound Dressing to Interleukin 1 and Interleukin 6 in Diabetic wound

Werna Nontji, Suni Hariati, Rosyidah Arafat

Abstract views = 2596 times | downloads = 30416 times


Introduction: Holistic wound care is one of the ways to prevent gangrene and amputation, modern wound dressing is more effective than convensional with increasing transforming growth factor and cytokine, especially interleukin. This study aims to identify the effectiveness of Modern and Convensional Wound Dressing to Interleukin 1 (IL-1) and Interleukin 6 (IL-6) in Diabetic wound.

Methods:A Quasi eksperimental pre-post with control group design was used. The intervention given was modern wound dressing and Control group by convensional wound dressing, This study was conducted in Makassar with 32 samples (16 in intervention group and 16 in control group). 

Results: The result of Pooled T- test showed that p = 0.00 (p < 0.05), it means that there was signifi cant correlation between modern wound dressing to IL-6 and IL-1 than Convensional wound dressing.  
Conclusion: Process of wound healing was produced growth factor and cytokine (IL-1 and IL-6), it will stimulated by wound dressing, modern wound dressing (Calcium alginat) can absorb wound drainage, non oklusive, non adhesif, and autolytic debridement.


modern wound dressing; interleukin 1 (IL-1); interleukin 6 (IL-6)

Full Text:



Ebihara, N., Matsuda, A., Nakamura, S., Matsuda, H., & Murakami, A. 2011. Role of the IL-6 Classic- and Trans-

Signaling Pathways in Corneal SterileInf lammation and Wound

Healing. (Online) ( diakses tanggal 12 Februari 2012, Jam 13.00 WIB)

Japan Guyton & Hall. 2006. Fisiologi Kedokteran. Kovazs & Dipietro. 1994. Fibrogeniccytokines and Connective

Tissue Production. USA: Loyola University. Jakarta: EGC.

Kristianto, H. 2010. Perbandingan perawatan luka teknik moderen dan konvensional terhadap Transforming Growth

FactorBeta (TGF 8) dan respons nyeri pada luka diabetes Mellitus. Depok: Makara UI.

Sri Gitarja. 2008. Perawatan Luka Diabetik. Bogor: Wocare Publishing.

Werner, S & Grose, R. 2003. Regulation of Wound Healing by Growth Factors and Cytokines. Physiol Rev. 83: 835–870.

(Online) ( diakses tanggal 12 februari 2012, Jam 13.20 WIB)


  • There are currently no refbacks.

Copyright (c) 2016 Jurnal NERS

This journal is indexed by:





This journal is published by:


          Faculty of Nursing Universitas Airlangga in Collaboration with Indonesian National Nurses Association


Creative Commons License

This journal (p-ISSN:1858-3598; e-ISSN:2502-5791) is licensed under a Creative Commons Attribution 4.0 International License


Current Stats

Previous Stats