Povidone Iodine 1 % and Normal Saline as a Gargling Solution to Prevent Oral Mucousitis
Introduction: Oral mucositis could affect children’s health status. The purpose of this study was to identify the difference of effectiveness between gargling with povidone iodine 1% and normal saline solutions in 5-15 years old children who received chemotherapy.
Method: This study used pre-experiment static group comparison design. There were 18 respondents who divided into 2 treatment groups and 1 control group. The independent variable was gargling use solutions of povidone iodine 1% and normal saline and the dependent variable was oral mucositis.The level of mucositis measured using multiple variable mucositis rating scales then analyzed by means of statistical test mann whitney u test with significance level of α≤0.05.
Result: The result showed that there were no difference between gargling use solutions of povidone iodine 1% and normal saline (p=0.930). Thus normal saline as good as povidone iodine 1% to prevent oral mucositis. It can be concluded that there was no difference between the use of povidone iodine 1% and normal saline as mouthwash to prevent oral mucositis.
Discussion: It is recommended that patient with chemotherapy should be gorgled with povidone iodine and normal saline.
Gipsland Oncology Nurses Group, 2007. Cancer Care Guidelines. Gippsland: GONG Publishing, pp.1-4.
Hartanto, W., 2007. Terapi Cairan Dan Elektrolit Perioperatif. Thesis tidak untuk dipublikasikan. Bogor: Fakultas Kedokteran Universitas Padjajaran, hlm. 28-29.
Japardi, I., 2009. Gejala Kanker Pada Anak-anak., (online), (http://rumahkanker.com/content/ view/64/62/, diakses tanggal 21 Mei 2009, jam 13.00 WIB).
Joanna Bridge Intitute, 1998. Prevention and Treatment of Oral Mucositis in Cancer Patients. Journal of Best Practice, 2 (3) , pp. 1-6.
Keshav, S., 2004. The Gastro Intestinal System At A Glance. Massachussets: Black Well Publishing, pp.12-17.
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