Management of Cough
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Cough is the most frequent symptom for which patients consult with their health care provider throughout the world. This symptom could be happened not only in sick individuals but also healthy individuals. At some stage, it is distressing, inhibits normal social activities, and reduces quality of life. Besides these detrimental effects, cough is the most effective defense mechanism to eliminate foreign materials, including various pathogens, from the respiratory tract. It begins with a series of breathing maneuvers which triggers sudden expulsion of air which is divided into three phases, i.e. inspiration, compression, and expiration phase. Cough occurs due to activation of mechanical or chemical sensory receptors in the larynx and lower respiratory tract which stimulates reflex arc complex. This stimulus is then transmitted to the afferent pathway to the cough center in the medulla through the vagus nerve to trigger expiration muscles to produce cough. It is important to know the cause of cough because cough is an indicator for patients and doctors for early diagnosis and therapy of disease. Therefore, cough is classified into acute, subacute, and chronic according to its duration. Available medications for symptomatic management of cough are inadequate due to lack of proven efficacy and/or their undesirable or intolerable side effects. This article aims to provide information on cough management to improve therapeutic effectiveness and patient quality of life.
Barry SJ, Dane AD, Morice AH, et al. The Automatic Recognition and Counting of Cough. Cough 2006; 2: 8.
Ogawa H, Fujimura M, Ohkura N, et al. Chronic Cough Management: Dealing with a Sensation of Irritation in the Throat. Respirology 2013; 18: 1278–1279.
Chung KF, Mazzone SB. 30 - Cough. In: Broaddus VC, Mason RJ, Ernst JD, et al. (eds). Philadelphia: W.B. Saunders, pp. 497-514.e5.
Morice AH. A New Way to Look at Acute Cough in the Pharmacy. Clin Pharm; 9. Epub ahead of print 1 April 2017. DOI: 10.1211/CP.2017.20202484.
De Blasio F, Virchow JC, Polverino M, et al. Cough Management: A Practical Approach. Cough 2011; 7: 7.
Chung KF. Management of Cough. Cough: Causes, Mechanisms and Therapy 2003; 283–297.
Morice AH, McGarvey L, Pavord I. Recommendations for the Management of Cough in Adults. Thorax 2006; 61: i1 LP-i24.
McCool FD. Global Physiology and Pathophysiology of Cough: ACCP Evidence-Based Clinical Practice Guidelines. Chest 2006; 129: 48S-53S.
Polverino M, Polverino F, Fasolino M, et al. Anatomy and Neuro-Pathophysiology of the Cough Reflex Arc. Multidiscip Respir Med 2012; 7: 5.
Reynolds SM, Mackenzie AJ, Spina D, et al. The Pharmacology of Cough. Trends Pharmacol Sci 2004; 25: 569–576.
Ojoo JC, Everett CF, Mulrennan SA, et al. Management of Patients with Chronic Cough Using a Clinical Protocol: A Prospective Observational Study. Cough 2013; 9: 2.
Song W-J, Chang Y-S. Cough Hypersensitivity as a Neuro-Immune Interaction. Clin Transl Allergy 2015; 5: 24.
Shimizu H, Hayashi M, Saito Y, et al. Classification of Chronic Cough by Systematic Treatment Cascade Trial Starting with Beta Agonist. Cough 2013; 9: 4.
Matsumoto H, Tabuena RP, Niimi A, et al. Cough Triggers and Their Pathophysiology in Patients with Prolonged or Chronic Cough. Allergol Int 2012; 61: 123–132.
Kahrilas PJ, Smith JA, Dicpinigaitis P V. A Causal Relationship between Cough and Gastroesophageal Reflux Disease (GERD) has been Established: A Pro/Con Debate. Lung 2014; 192: 39–46.
Ogawa H, Fujimura M, Ohkura N, et al. Atopic Cough and Fungal Allergy. J Thorac Dis Vol 6, Suppl 7 (October 2014) J Thorac Dis (Chronic Cough), http://jtd.amegroups.com/article/view/3296 (2014).
Vertigan AE, Murad MH, Pringsheim T, et al. Somatic Cough Syndrome (Previously Referred to as Psychogenic Cough) and Tic Cough (Previously Referred to as Habit Cough) in Adults and Children: CHEST Guideline and Expert Panel Report. Chest 2015; 148: 24–31.
Pontifex E, Williams MT, Lunn R, et al. The Effect of Huffing and Directed Coughing on Energy Expenditure in Young Asymptomatic Subjects. Aust J Physiother 2002; 48: 209–213.
Bott J, Blumenthal S, Buxton M, et al. Guidelines for the Physiotherapy Management of the Adult, Medical, Spontaneously Breathing Patient. Thorax 2009; 64: i1 LP-i52.
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