Risk Factor Related to Mortality of Diabetic Ketoacidosis Patients in Dr. Soetomo General Hospital Surabaya

Alviano Satria Wibawa, Hermina Novida, Muhammad Faizi, Deasy Ardiany

= http://dx.doi.org/10.20473/juxta.V11I12020.36-40
Abstract views = 177 times | downloads = 368 times


Introduction: Diabetic ketoacidosis (DKA) is a complication of diabetes mellitus which has a high risk of mortality. Mortality in DKA patients in developed countries is less than 5%, some other sources mention 5-10%, 2-10%, or 9-10%. Mortality events at clinics with simple facilities and elderly patients can reach 25-50%. The mortality rate of DKA patients is generally higher in infection conditions, especially in developing countries and in septic patients. Several factors such as age, sex, and high blood glucose can increase mortality risk of DKA patients. Other risk factors such as history of discontinued insulin therapy, impaired bicarbonate levels, pH, and increased leukocytes of DKA patients due to infection, abnormal albumin levels, electrolyte disturbances, and Serum Creatinine (SK) were thought to affect mortality of DKA patients. The purpose of this study was to determine the risk factors associated with mortality of DKA patients in Dr. Soetomo General Hospital Surabaya.


Methods: The method used in this study was observational analytic involving 63 adult patients diagnosed with DKA with analysis using Chi-Square test.


Results: From 63 patients included in this study, 37 patients diagnosed with DKA died and 26 patients lived. In a multivariate analysis, DKA severity with p = 0.001 (p < 0.005) was identified as having a relationship with mortality of DKA patients Dr. Soetomo General Hospital Surabaya.


Conclusion: Severity is the only risk factor associated with mortality of DKA patients in Dr. Soetomo General Hospital Surabaya.

Full Text:



George J, Mishra A, Iyadurai R. Correlation between the Outcomes and Severity of Diabetic Ketoacidosis: A Retrospective Pilot Study. J Fam Med Prim Care. 2018;7(4):787-790. Doi:10.4103/Jfmpc.Jfmpc_116_18

Cheng P, Hsu S, Cheng Y. Association between Serum Albumin Concentration and Ketosis Risk in Hospitalized Individuals with Type 2 Diabetes Mellitus. 2016;2016:1-5. Doi:10.1155/2016/1269706

American Diabetes Association. Standards of Medical Care in Diabetes-2009. In: Diabetes Care. Vol 32. ; 2009:61. Doi:10.2337/Dc09-S013

Suwarto S, Sutrisna B, Waspadji S, Pohan HT. Predictors of Five Days Mortality in Diabetic Ketoacidosis Patients : A Prospective Cohort Study. 2008;1:18-23.

Malone M, Gennis V, Goodwin JS. Characteristics of Diabetic Ketoacidosis in Older Versus Younger Adults. 1992:3-7.

Sinaga M. Karakteristik Penderita Diabetes Mellitus dengan Komplikasi yang Dirawat Inap di Rumah Sakit Vita Insani Pematang Siantar. Respository USU. 2011.

Gotera W, Agung Budiyasa D. Penatalaksanaan Ketoasidosis Diabetik (Kad). J Intern Med. 2010;11(2).

American Diabetic Association. Diagnosis and Classification of Diabetes Mellitus. Diabetes Care. 2011;34(SUPPL.1). Doi:10.2337/Dc11-S062

Ullah S, Khan N, Zeb H, Tahir H. Metabolic Ketoacidosis with Normal Blood Glucose : A Rare Complication of Sodium – Glucose Cotransporter 2 Inhibitors. 2016:0-2. Doi:10.1177/2050313X16675259

Arifin AL, N N, SHK K. Krisis Hiperglikemia pada Diabetes Mellitus. (3):1-16.

Prabawati M. Studi Penggunaan Albumin pada Pasien Diabetes Melitus dengan Gangren. Repos Unair. 2006.

Huang I. Patofisiologi dan Diagnosis Penurunan Kesadaran pada Penderita Diabetes Mellitus. Medicinus. 2018;5(2):48-57. Doi:10.19166/Med.V5i2.1169

Elmehdawi RR, Elmagerhei HM. Profile of Diabetic Ketoacidosis at a Teaching Hospital in Benghazi , Libyan Arab Jamahiriya. 2010;16(3).


  • There are currently no refbacks.

Copyright (c) 2020 JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga




Creative Commons License

JUXTA (p-ISSN: 1907-3623, e-ISSN: 2684-9453) is licensed under Creative Commons Attribution-ShareAlike 4.0 International License.

 View JUXTA Stats