Hidayaturrahmi Hidayaturrahmi, Viskasari Pintoko Kalanjati

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Bell’s palsy  disease  is  an acute  idiopathic  peripheral  facial  paralysis  involving  the facial nerve. This disease. This disease is characterized by paralysis and weakness of the facial muscles unilateral with sudden onset and  peak symptoms within a few days.  The etiology  of  this disease  can not be explained  properly. However, some clinical data and immunology shows that the bell’s palsy is  thought to be caused by latent Herpes simplex virus tipe 1 (HSV-1) which is  reactivated  at ganglia  geniculatum  so may provoke an autoimmune reaction against peripheral nerve myelin, leading to the demyelination of facial nerve (N.VII). In the acute phase,  examination of peripheral blood lymphocytes was found a significant reduction of  the percentage of peripheral T lymphocytes and an increase in the percentage of B lymphocytes. In this review, we will also discuss steroids and antiviral therapy as a treatment of Bell’s palsy is currently.


Bell’s palsy; herpes simplex virus tipe 1; pharmacology; virus herpes simplex tipe 1; farmakologi

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