Comparison of pregnancy rates on day 3 and day 5 embryo transfer in In Vitro Fertilization (IVF)
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Objectives: To identify the success rates of pregnancy on the third and fifth day embryo transfer at Graha Amerta Hospital, Surabaya, Indonesia.
Materials and Methods: This study used comparative cross sectional design. Data were taken from medical record of IVF participants who met the inclusion and exclusion criteria at Graha Amerta Hospital for the period of January 2016 - December 2016.
Results: Successful pregnancy rates were found in this research. The embryo transfer on the third day and the fifth day were 35% and 49.3% respectively. In other words, the rates of pregnancy success were not affected by embryo transfer on the third day and the fifth day in the medical record sample as it had p value of 0.090.
Conclusion: Embryo transfer on the third and fifth days had the same rates of pregnancy success in IVF participants at Graha Amerta Hospital, Surabaya, Indonesia.
World Health Organization (WHO). WHO manual for the standardized investigation and diagnosis of the infertile couple. Cambridge: Cambridge University Press; 2000.
Van der Borght M, Wyns C. (2018). Fertility and infertility: Definition and epidemiology. Clinical Biochemistry. 2018;62:2-10.
Spitzer D, Haidbauer R, Corn C, et al. Effects of embryo transfer quality on pregnancy and live birth delivery rates. Journal of Assisted Reproduction and Genetics. 2011;29(2):131-5.
Edwards RG, Brody SA. History and ethics of assisted human conception. In: Principles and practice of assisted human reproduction. Philadelphia: Saunders; 1995, p. 17–47.
Hatırnaz Åž, Kanat Pektaş M. Day 3 embryo transfer versus day 5 blastocyst transfers: A prospective randomized controlled trial. Turk J Obstet Gynecol. 2017;14(2):82-8.
Dahiya M, Rupani K, Yu S, et al. Embryo transfer day does not affect the initial maternal serum beta-hCG levels: A retrospective cohort study. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2017;212:75-9.
Papanikolaou. Rbmojournal; 2018 [cited 2018 Oct 18] Available from https://www.rbmo journal. com/article/S1472-6483(10)60981-9/pdf
Martins WP, Nastri CO, Rienzi L, et al. Blastocyst vs cleavage-stage embryo transfer: systematic review and meta-analysis of reproductive out-comes. Ultrasound Obstet Gynecol. 2017;49(5): 583-91.
Kaartinen N, Das P, Kananen K, et al. (2015). Can repeated IVF–ICSI-cycles be avoided by using blastocysts developing from poor-quality cleavage stage embryos? Reproductive BioMedicine Online. 2015;30(3):241-7.
Lee C, Lee T, Huang C, et al. Detection of early cleavage embryos improves pregnancy and delivery rates of Day 3 embryo transfer during I in vitro fertil-ization. Taiwanese Journal of Obstetrics and Gynecology. 2016;55(4):558-62.
Herbemont C, Sarandi S, Boujenah J, et al. Should we consider day-2 and day-3 embryo morphology before day-5 transfer when blastocysts reach a similar good quality? Reproductive BioMedicine Online. 2017;35(5):521-8.
Adamson G, Abusief M, Palao L, et al. (2016). Improved implantation rates of day 3 embryo transfers with the use of an automated time-lapse–enabled test to aid in embryo selection. Fertility and Sterility. 2016:105(2);369-375.e6.
Kumbak B, Oral E, Karlikaya G, et al. Serum oestradiol and beta-HCG measurements after day 3 or 5 embryo transfers in interpreting pregnancy outcome. Reprod Biomed Online. 2006;13(4):459-64.
Racowsky. rbmonline.com. [internet] Rbmonline. com. [cited 2018 Oct 18] Available at: http://www. rbmonline.com/Article/807
Revelli A, Canosa S, Carosso A, et al. Impact of the addition of Early Embryo Viability Assessment to morphological evaluation on the accuracy of embryo selection on day 3 or day 5: a retrospective analysis. J Ovarian Res. 2019;12(1):73.
Mastenbroek S, van der Veen F, Aflatoonian Aet al. Embryo selection in IVF. Hum Reprod. 2011;26(5):964-6.
Tiegs A, Franasiak J. The embryo day 3 versus day 5 ET. Encyclopedia of Reproduction. 2018; p. 278-83.
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