Placenta Accreta Spectrum in delivered women is associated with history of curettage: A case-control study at Dr. Moewardi General Hospital, Surakarta, Indonesia
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HIGHLIGHTS
- Placenta Accreta Spectrum cases rise in proportion to the high frequency of uterine wall damage.
- A significant association was found between curettage history and Placenta Accreta Spectrum.
ABSTRACT
Objective: Placenta Accreta Spectrum (PAS) involves abnormal placental adherence to the myometrium, causing severe obstetric hemorrhage and increased maternal morbidity and mortality (3,000–5,000 mL blood loss). Its global incidence has risen from 0.12% to 0.31%, linked to uterine trauma from cesarean sections or curettage. This study evaluates the association between curettage history and PAS.
Materials and Methods: This study employed an analytical observational design with a case-control approach. Purposive sampling was utilized, resulting in the inclusion of 134 participants who met the predefined criteria. The study population consisted of women who delivered and were referred to Dr. Moewardi General Hospital, Surakarta, Indonesia, between May 2022 and May 2024. Data were analyzed using IBM SPSS version 25. The Chi-square test was applied to assess the association between variables at a significance level of p < 0.05, while logistic regression analysis was conducted to identify the most influential variables.
Results: The study cohort comprised 67 patients diagnosed with PAS and 67 without PAS. A statistically significant association was observed between a history of curettage and PAS, as determined by the Chi-square test, with a p-value of 0.000. Logistic regression analysis further confirmed this association, yielding a p-value of 0.001 and an odds ratio (OR) of 5.769 (95% CI: 2.090–15.928) for a history of curettage.
Conclusion: A history of curettage is significantly associated with the development of PAS. Patients with a prior curettage procedure are 5.769 times more likely to develop PAS compared to those without such a history.
Arifin Z. Implementasi pelayanan kesehatan dalam penurunan angka kematian ibu [Health service implementation in reducing maternal mortality rate]. Jurnal Penelitian Kesehatan “SUARA FORIKES” (Journal of Health Research “Forikes Voice”). 2023;14(1):6–10. doi: 10.33846/sf14102.
Badan Pusat Statistik Provinsi Jawa Tengah. Hasil long form sensus penduduk 2020 Provinsi Jawa Tengah [Internet]. Badan Pusat Statistik Provinsi Jawa Tengah; 2020 [cited 2024 Aug 24]. Available from: https://jateng.bps.go.id/publication/2023/02/ 10/5b211edf75a0b50a74c56264/hasil-long-form-sensus-penduduk-2020-provinsi-jawa-tengah.html.
Agarwal S, Ranjan M, Sachan S, et al. Antepartum hemorrhage and its maternal and perinatal outcome: An experience at a hospital in North India. J Family Med Prim Care. 2023;12(12):3204-08. doi: 10. 4103/jfmpc.jfmpc_692_23. Epub 2023 Dec 21. PMID: 38361908; PMCID: PMC10866261.
Negesa Beyene B, Jara Boneya D, Gelchu Adola S, et al. Factors associated with postpartum hemor-rhage in selected Southern Oromia hospitals, Ethiopia, 2021: an unmatched case-control study. Front Glob Womens Health. 2024;5:1332719. doi: 10.3389/fgwh.2024.1332719. PMID: 38549584; PMCID: PMC10972879.
Ramadhan JW, Rasyid R, Rusnita D. Profil pasien hemorrhagic postpartum di RSUP Dr. M. Djamil Padang [Profile of postpartum hemorrhage patients at Dr. M. Djamil Hospital, Padang]. Jurnal Kesehatan Andalas. 2019;8(2S):46-53. doi: 10. 25077/jka.v8i2S958.
Utami NA, Amirsyah M, Indirayani I, et al. Gambaran kejadian perdarahan postpartum di RSUD ZA Banda Aceh Tahun 2019-2020 [Profile of postpartum bleeding at AZ Hospital, Banda Aceh]. Jurnal Kedokteran Syiah Kuala. 2022;22(3): 20–5. doi: 10.24815/jks.v22i3.25157.
El Gelany S, Mosbeh MH, Ibrahim EM, et al. Placenta Accreta Spectrum (PAS) disorders: incidence, risk factors and outcomes of different management strategies in a tertiary referral hospital in Minia, Egypt: a prospective study. BMC Pregnancy Childbirth. 2019;19(1):313. doi: 10.1186/s12884-019-2466-5. PMID: 31455286; PMCID: PMC6712589.
Mirani P, Lestari PM, Murti K, et al. Placenta accreta spectrum disorder: An updated literature review. Jurnal Kedokteran dan Kesehatan Indonesia. 2023;14(3):344-56. doi: 10.20885/ JKKI.Vol14.Iss3.art15.
Morlando M, Collins S. Placenta accreta spectrum disorders: Challenges, risks, and management strategies. Int J Womens Health. 2020;12:1033-45. doi: 10.2147/IJWH.S224191. PMID: 33204176; PMCID: PMC7667500.
Imafuku H, Tanimura K, Shi Y, et al. Clinical factors associated with a placenta accreta spectrum. Placenta. 2021;112:180-4. doi: 10.1016/j. placenta. 2021.08.001. Epub 2021 Aug 5. PMID: 34375912.
Dawood A, Elsokary A, Shazly S. Association between characteristics of patients having a previous cesarean delivery and the presence of placenta accreta spectrum: A case-control study. Evidence Based Women’s Health Journal. 2023;13(3):303-10. doi: 10.21608/ebwhj.2023. 214406.1253.
Pegu B, Thiagaraju C, Nayak D, et al. Placenta accreta spectrum. A catastrophic situation in obstetrics. Obstet Gynecol Sci. 2021;64(3):239-47. doi: 10.5468/ogs.20345. Epub 2021 Mar 24. PMID: 33757280; PMCID: PMC8138076.
Hussein AM, Elbarmelgy RA, Elbarmelgy RM, et al. Prospective evaluation of impact of post-Cesarean section uterine scarring in perinatal diagnosis of placenta accreta spectrum disorder. Ultrasound Obstet Gynecol. 2022;59(4):474-82. doi: 10.1002/uog.23732. Epub 2022 Mar 8. PMID: 34225385; PMCID: PMC9311077.
Soares MJ, Iqbal K, Kozai K. Hypoxia and placental development. Birth Defects Res. 2017; 109(17):1309-29. doi: 10.1002/bdr2.1135. PMID: 29105383; PMCID: PMC5743230.
Dahlan MS. Besar sampel dan cara pengambilan sampel dalam penelitian kedokteran dan kesehatan [Sample size and sampling method in medical and health research]. Jakarta: Salemba Medika; 2016. p. 46–60.
You H, Wang Y, Han R, et al. Risk factors for placenta accreta spectrum without prior cesarean section: A case-control study in China. Int J Gynaecol Obstet. 2024;166(3):1092-9. doi: 10.1002/ijgo.15493. Epub 2024 Apr 4. PMID: 38573157.
Baldwin HJ, Patterson JA, Nippita TA, et al. Antecedents of abnormally invasive placenta in primiparous women: Risk associated with gynecologic procedures. Obstet Gynecol. 2018; 131(2):227-33. doi: 10.1097/AOG.00000000 00002434. PMID: 29324602.
Burke SD, Zsengellér ZK, Karumanchi SA, et al. A mouse model of placenta accreta spectrum. Placenta. 2020;99:8-15. doi: 10.1016/j.placenta. 2020.06.006. Epub 2020 Jul 15. PMID: 32716845.
Rac MW, Dashe JS, Wells CE, et al. Ultrasound predictors of placental invasion: the Placenta Accreta Index. Am J Obstet Gynecol. 2015;212(3): 343.e1-7. doi: 10.1016/j.ajog.2014.10.022. Epub 2014 Oct 18. PMID: 25446658.
Qatrunnada A, Antonius PA, Yusrawati Y. Faktor risiko dan luaran maternal plasenta akreta di RSUP Dr. M. Djamil Padang [Risk factors and maternal outcome of placenta accreta at Dr. M. Djamil Hospital, Padang]. Indonesian Journal of Obstetrics & Gynecology Science. 2018;1(2):97-102. doi: 10.24198/obgynia.v1n2.94.
Kasraeian M, Hashemi A, Hessami K, et al. A 5-year experience on perinatal outcome of placenta accreta spectrum disorder managed by cesarean hysterectomy in southern Iranian women. BMC Womens Health. 2021;21(1):243. doi: 10.1186/ s12905-021-01389-z. PMID: 34130685; PMCID: PMC8207599.
Del Negro V, Aleksa N, Galli C, et al. Ultrasonographic diagnosis of placenta accreta spectrum (PAS) disorder: Ideation of an ultra-sonographic score and correlation with surgical and neonatal outcomes. Diagnostics (Basel). 2020; 11(1):23. doi: 10.3390/diagnostics 11010023. PMID: 33375532; PMCID: PMC 7824485.
Kyozuka H, Yamaguchi A, Suzuki D, et al. Risk factors for placenta accreta spectrum: findings from the Japan environment and Children's study. BMC Pregnancy Childbirth. 2019;19(1):447. doi: 10.1186/s12884-019-2608-9. PMID: 31775687; PMCID: PMC6882023.
Cunningham FG, Leveno KJ, Bloom SL, et al. Williams Obstetrics. United States of America: Mc Graw Hill Education; 2018. p. 80–110.
Silver R. Placenta Accreta Syndrome. Boca Raton: CRC Press; 2017. p. 13–29.
Kayem G, Seco A, Vendittelli F, et al Risk factors for placenta accreta spectrum disorders in women with any prior cesarean and a placenta previa or low lying: a prospective population-based study. Sci Rep. 2024;14(1):6564. doi: 10.1038/s41598-024-56964-9. PMID: 38503816; PMCID: PMC10951207.
Bowman ZS, Eller AG, Bardsley TR, et al. Risk factors for placenta accreta: a large prospective cohort. Am J Perinatol. 2014;31(9):799-804. doi: 10.1055/s-0033-1361833. Epub 2013 Dec 12. PMID: 24338130.
Flo K, Widnes C, Vårtun Å, et al. Blood flow to the scarred gravid uterus at 22-24 weeks of gestation. BJOG. 2014;121(2):210-5. doi: 10.1111/1471-0528.12441. Epub 2013 Oct 1. PMID: 24112289.
Jenabi E, Salehi AM, Masoumi SZ, et al. Maternal smoking and the risk of placenta accreta spectrum: A systematic review and meta-analysis. Biomed Res Int. 2022;2022:2399888. doi: 10.1155/2022/ 2399888. PMID: 35860796; PMCID: PMC929 3521.
Guo Z, Han X, Zheng W, et al. Placenta accreta spectrum among multiple gestation: A retrospective analysis based on a Chinese population. Front Endocrinol (Lausanne). 2022;13:862785. doi: 10.3389/fendo.2022.862785. PMID: 35663330; PMCID: PMC9158523.
Modest AM, Toth TL, Johnson KM, et al. Placenta accreta spectrum: In vitro fertilization and non-in vitro fertilization and placenta accreta spectrum in a Massachusetts Cohort. Am J Perinatol. 2021; 38(14):1533-9. doi: 10.1055/s-0040-1713887. Epub 2020 Jul 5. PMID: 32623707.
Salmanian B, Fox KA, Arian SE, et al. In vitro fertilization as an independent risk factor for placenta accreta spectrum. Am J Obstet Gynecol. 2020;223(4):568.e1-568.e5. doi: 10.1016/j.ajog. 2020.04.026. Epub 2020 Apr 30. PMID: 32360847.
Vieira MC, Rijken MJ, Braun T, et al. The relation between maternal obesity and placenta accreta spectrum: A multinational database study. Acta Obstet Gynecol Scand. 2021;100 Suppl 1:50-7. doi: 10.1111/aogs.14075. PMID: 33811335.
Zhang L, Bi S, Du L, et al. Effect of previous placenta previa on outcome of next pregnancy: a 10-year retrospective cohort study. BMC Pregnancy Childbirth. 2020;20(1):212. doi: 10. 1186/s12884-020-02890-3. PMID: 32293318; PMCID: PMC7161269.
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