Effect of High Frequency Transcranial Magnetic Stimulation (TMS) on Extensor Digitorum Communis Muscle Strength in Ischemic Stroke Patients

Bastianus Alfian Juatmadja, Meisy Andriana, Rwahita Satyawati

= http://dx.doi.org/10.20473/spmrj.v2i1.17014
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Abstract


Abstract

Background: Stroke may disrupt a patient’s motor function, consequently affecting the quality of life. A stroke surviving brain has the ability to repair itself through neuroplasticity mechanism. Transcranial Magnetic Stimulation (TMS) is a non-invasive device which can be used to stimulate the lesioned part of the brain in hope of triggering neuroplasticity.

Aims: To find prove of the repetitive Transcranial Magnetic Stimulation (rTMS) effect on extensor digitorum communis muscle strength improvement in ischemic stroke patients.

Methods: Subjects suitable with the inclusion criteria (N=18) were divided into two groups,  control group and intervention group. The control group underwent conventional therapy exclusively every day for 5 days in a row, while the intervention group underwent rTMS therapy and conventional therapy every day for 5 days in a row. Extensor digitorum communis muscle strength was measured using surface electromyography (sEMG) before and after treatment.

Result: Significant increase of sEMG numbers were found on control group (p=0,003) and intervention group (p=0,001). The increase from the intervention group was not different when compared to the control group (p=0,067).

Conclusion: TMS can increase extensor digitorum communis muscle strength but with no difference with a conventional therapy.


Keywords


Transcranial Magnetic Stimulation, TMS, neuroplasticity, surface electromyography, Extensor digitorum communis muscle strength, subacute ischemic stroke

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References


Zorowits RD. 2010. Stroke. In: Cuccurullo SJ: Physical Medicine and Rehabilitation Board Review. 2nd ed. New York: Demos medical, pp. 40-87.

Jauch EC, Saver JL, Adams HP, Bruno A, Connors JJ, Demaerschalk BM, Khatri P, McMullan PW, Qureshi AI, Rosenfield, K, Scott PA, Summers DR, Wang DZ, Wintermark M, Yonas H. 2013. American Heart Association. Guidelines for The Early Management of Patients with Acute Ischemic Stroke.

Riskesdas, 2013. Riset Kesehatan Dasar. Jakarta: Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan RI.

Khedr EM, Abdel-Fadeil MR, Farghali A, Qaid M. 2009. Role of 1 and 3 Hz Repetitive Transcranial Magnetic Stimulation on Motor Function Recovery After Acute Ischaemic Stroke. European Journal of Neurology. 16: 1323 – 1330.

Khedr EM, Etraby AE, Hemeda M, Nasef AM, Razek AAE. 2010. Long-Term Effect of Repetitive Transcranial Magnetic Stimulation on Motor Function Recovery After Acute Ischemic Stroke. Acta Neurologica Scandinavica. 121: 30–37.

Gates DH, Walters LS, Cowley J, Wilken JM, Resnik L. 2016. Range of Motion Requirements for Upper-Limb Activities of Daily Living. The American Journal of Occupational Therapy. 70 (1): 7001350010p1–7001350010p10.

Hsu WY, Cheng C, Liao K, Lee I, Lin Y. 2012. Effect of Repetitive Transcranial Magnetic Simulation on Motor Function in Patient with Stroke a Meta-analysis. Journal of The American Heart Association. 43 (7): 1849 – 57.

Zhang L, Hu X, Luo J, Li L, Chen X, Huang R, Pei Z. 2013. Physical Exercise Improves Functional Recovery Through Mitigation of Autophagy, Attenuation of Apoptosis and Enhancement of Neurogenesis After MCAO in Rats. BMC neuroscience. 14 (1): 46

Pin-Barre C, Laurin J. 2015. Physical exercise as a diagnostic, rehabilitation, and preventive tool: influence on neuroplasticity and motor recovery after stroke. Neural plasticity.15: 608581.

Ploughman M, Windle V, MacLellan CL, White N, Doré JJ, Corbett D. 2009. Brain-derived neurotrophic factor contributes to recovery of skilled reaching after focal ischemia in rats. Stroke, 40 (4): 1490-1495.

Rajan ST, Ghilardi MF, Wang HY, Mazzon E, Bramanti P, Restivo D, Quartarone A. 2017. Mechanism of Action For rTMS: A Working Hypothesis Based on Animal Studies. Frontiers in Physiology. 8: 457

Lasek-Bal A, Jędrzejowska-Szypułka H, Różycka J, Bal W, Holecki M, Duława J, Lewin-Kowalik J. 2015. Low Concentration of BDNF in The Acute Phase of Ischemic Stroke as A Factor in Poor Prognosis in Terms of Functional Status of Patients. Medical Science Monitor. 21: 3900–3905

Gupta VK, You Y, Gupta BV, Klistorner A, Graham SL. 2013. TrkB Receptor Signalling: Implications in Neurodegenerative, Psychiatric and Proliferative Disorders. International Journal of Molecular Sciences. 14: 10122 – 10142

Kotlęga D, Peda B, Zembroń-Łacny A, Gołąb-Janowska M, Nowacki P. 2017. The Role of Brain-Derived Neurotrophic Factor and Its Single Nucleotide Polymorphisms in Stroke Patients. Polish Journal of Neurology and Neurosurgery. 51: 240 – 246

Lopez-Ibor JJ, Lopez-Ibor M, Pastrana J. 2008. Transcranial Magnetic Stimulation. Current Opin in Psychiatry. 21: 640-644.

Haraldsson HM, Ferrarelli F, Kalin NH, Tononi G. 2004. Transcranial Magnetic Stimulation in The Investigation and Treatment of Schizophrenia: a Review. Schizophr Res. 71:1–16.

Burt T, Lisanby SH, Sackheim HA. 2002. Neuropsychiatric Applications of Transcranial Magnetic Stimulation: A Meta-analysis. International Journal of Neuropsychopharmacol. 5:73–103

Guse B, Falkai P, Wobrock T. 2009. Cognitive Effects of High-Frequency Repetitive Transcranial Magnetic Stimulation: A Systematic Review. Journal of Neural Transmission. 117 (1): 105 – 122.

Chang WH, Kim YH, Bang OY, Kim ST, Park YH, Lee PK. 2010. Long-term Effects of rTMS on Motor Recovery in Patients After Subacute Stroke. Journal of Rehabilitation Medicine. 42:758 –764.


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