BACTERIA CAUSED SEPSIS BIOMARKERS

Artaria Tjempakasari, Nasronudin Nasronudin

= http://dx.doi.org/10.20473/ijtid.v5i3.238
Abstract views = 284 times | views = 179 times

Abstract


Sepsis is a clinical condition of patients with serious infections that show a systemic inflammatory response, with or without a positive blood culture. sepsis is one of the most frequent causes of death in patients in intensive care units. We are at urgent need for biomarkers and reliable measurements that can be applied to risk stratification of septic patients and that would easily identify those patients at the highest risk of a poor outcome. Such markers would be of fundamental importance to decision making for early intervention therapy. Pro-inflammatory cytokines such as tumor necrosis factor- (TNF- ), interleukins-1,-6,-8 (IL-1, IL-6, IL-8) are postulated to play a major role in the pathogenesis of the syndrome. C-reactive protein (CRP) and procalcitonin (PCT) are among a few biomarkers that
incorporated into clinical practice although their precise role in the pathopysiology of sepsis and organ dysfunction still unclear.


Full Text:

PDF

Refbacks

  • There are currently no refbacks.




Copyright (c) 2015 Indonesian Journal of Tropical and Infectious Disease

View My Stats

IJTID Indexed by : 

       

 
IJTID (pISSN 2085-1103eISSN 2356-0991is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Institute of Tropical Disease - Airlangga University
Gedung Lembaga Penyakit Tropis Lt.1, Kampus C Universitas Airlangga
Jln. Mulyorejo Surabaya 60115, Indonesia
E-mail: ijtid@itd.unair.ac.id