Antioxidant Activity of Lip Balm Ethanol Extract Keji Beling Leaves (Strobilanthes crispus Blume) using The DPPH (2,2-diphenyl-1-picryhydrazyl) Method
Downloads
Keji beling leaves contained compounds that have the potential to act as moisturizers, namely flavonoids with catechins that function as high antioxidants in preventing free radicals. Keji beling leaf extract can be used as a preparation to overcome dry lips, namely as a moisturizer in the form of lip balm preparations. The purpose of this study was to formulate a lip balm from ethanol extract of keji beling leaves, and to determine the antioxidant activity. This research method included 70% ethanol extract of keji beling leaves with the maceration method and antioxidant activity, namely the DPPH method (2,2-diphenyl-1-picrylhydrazyl) with Vitamin C as a positive control (comparator). The results showed that formula 3 lip balm preparations with 70% ethanol extract of keji beling leaves had antioxidant activity with an IC50 value of 3.12 ppm in the very strong category.
Keywords: Antioxidant, Keji Beling Leaves (Strobilanthes crispus Blume), DPPH (2,2-diphenyl-1-picrylhydrazyl),
Lip Balm
Amalia, I., Prabandari, S. and Susiyarti (2021) ‘Formulasi dan Uji Sifat Fisik Lip Balm Ekstrak Etanol Buah Strawberry (Fragaria sp.)’, Politeknik Harapan Bersama, 09, pp. 3. Doctoral dissertation.
Apriani, S. and Pratiwi, F. D. (2021) ‘Aktivitas Antioksidan Ekstrak Bunga Telang (Clitoria ternatea L.) menggunakan Metode DPPH (2,2 Diphenyl-1-1-Picrylhydrazyl)’, Jurnal Ilmiah Kohesi, 5(3), pp. 83–89. Retrieved from https://kohesi.sciencemakarioz.org.
Ardini, D. and Sumardilah, S. D. (2021) ‘Effects of Aloe vera Extract Lip Balm as Lip Moisturizer’, Jurnal Kesehatan Metro Sali Walwali, 14(1), pp. 10–18. doi: 10.26630/jkm.v13i1.2677.
Arifin, B. and Ibrahim, S. (2018) ‘Struktur, Bioaktivitas dan Antioksidan Flavonoid’, Jurnal Zarah, 6(1), pp. 21–29. doi: 10.31629/zarah.v6i1.313.
Dali, A., Haeruddin, H., Miranda, W. O. Y. and Dali, N. (2017) ‘Uji Aktivitas Antioksidan Ekstrak Metanol Daun Pecah Beling (Strobilanthes crispus)’, Al-Kimia, 5(2), pp. 145–153. doi: 10.24252/al-kimia.v5i2.3642.
Fadhilah, Z. H., Perdana, F. and Syamsudin, R. A. M. R. (2021) ‘Telah Kandungan Senyawa Katekin dan Epigallocatechin Gallate (EGCG) sebagai Antioksidan pada Berbagai Jenis Teh’, Jurnal Pharmascience, 8(1), pp. 31.
doi: 10.20527/jps.v8i1.9122.
Fauzi, N. M., Santoso, J. & Riyanta, A.B. (2021) 'Uji kualitatif dan uji aktivitas antioksidan ekstrak etanolik buah maja (Aegle marmelos (L.) Corrêa) dengan metode DPPH', Jurnal Riset Farmasi, 1(1), pp. 1–8. doi: 10.29313/jrf.v1i1.25.
Haveni, D., Mastura and Sari, R. P. (2019) ‘Ekstrak Etanol Bunga Kertas (Bougainvillea Pink) sebagai Antioksidan dengan Menggunakan Metode DPPH’, CHEMICA: Jurnal Pendidikan Kimia dan Ilmu Kimia, 2(1), pp. 1–7. Retrieved from https://ejurnalunsam.id/index.php/katalis/article/view/1826.
Hidayah, F. and Resti Erwiyani, A. (2022) ‘Tingkat Pengetahuan, Sikap, dan Penggunaan Lip Balm untuk Perawatan Bibir di Kalangan Mahasiswa Farmasi Universitas Ngudi Waluyo’, Pro Health Jurnal Ilmiah Kesehatan, 4(1), pp. 179–183. doi: 10.35473/prohealth.v4i1.1553.
Kadu, M., Vishwasrao, S. & Singh, S. (2015) ‘Review Article on Natural Lip Balm’, International Journal of Research in Cosmetic Science, 5(1), pp. 1–7. Retrieved from https://www.researchgate.net/publication/301204451.
Kariem, V. E. & Maesaroh, I. (2022) ‘Standarisasi Mutu Simplisia Jahe (Zingiber officinale Roscoe) dengan Pengeringan Sinar Matahari dan Oven’, HERBALPHARMA: Journal of Herbal Pharmacological, 4(1), pp. 1–10. doi: 10.55093/herbalpharma.v4i1.178.
Leana, E.E. & Salvitri, I. (2022) 'Sediaan lip balm ekstrak etanol daun bayam merah (Amaranthus tricolor) dengan essences bunga mawar', XII, 8.5.2017, pp. 71–79. Retrieved from www.alging-us.com
Leo, R. & Daulay, A. S. (2022) 'Penentuan kadar vitamin C pada minuman bervitamin yang disimpan pada berbagai waktu dengan metode spektrofotometri UV', Journal of Health and Medical Science, 1(2), pp. 105–115. Retrieved from https://pusdikral-publishing.com/index.php/jkes/home
Limanda, D., Anastasia, S. D. & Desnita, R. (2019) 'Formulasi dan evaluasi stabilitas fisik sediaan lip balm minyak almond (Prunus almygdalus dulcis)', Jurnal Mahasiswa Farmasi Fakultas Kedokteran UNTAN, 4(1), pp. 1–9.
Luthfia, F. & Kurniawan, T.D. (2019) 'Pembuatan edible film bah kolang-kaling (Arenga pinatta) yang dipengaruhi jenis lilin lebah (beeswax) terhadap karakteristik edible film', Doctoral Dissertation Akademi Farmasi Putera Indonesia Malang, pp. 7–32.
Nurfitriyana, N., Yulikasari, D., Fatria, I. R. & Hardiyati, I. (2023) 'Formulasi sediaan lip balm ekstrak daun tin (Ficus carica L.) dan ubi jalar ungu (Ipomoea batatas L. Lam.)', ISTA Online Technologi Journal, 4(1), pp. 54–68. doi: 10.62702/ion.v4i1.77.
Nurraihana & Norfarzian (2013) 'Ulasan mini sifat fitokimia, farmakologi dan toksikologi dari', 20(5), pp. 2045–2056.
Pawestri, A., Yamlean, P.V. & Sumantri, S. (2024) 'Uji stabilitas fisik sediaan pelembab bibir (lip balm) ekstrak etanol buah tomat (Solanum lycopersicum L.)', Jurnal Pharmalcon, 13(1), pp. 434–447. doi: 10.35799/phal.13.2024.49321.
Salsabila, A. S., Dewi, I.K. & Atikah, N. (2022) 'Evaluasi mutu fisik sediaan lip balm kombinasi ekstrak kayu secang (Caesalpinias sappan L.) dan madu (Mel depuratum)', Borobudur Pharmacy Review, 2(2), pp. 50–54. doi: 10.31603/bphr.v2i2.7322.
Suharyanto, S. & Prima, D.Al.N. (2020) 'Penetapan kadar flavonoid total pada jus daun ubi jalar ungu (Ipomoea batatas L.) yang berpotensi sebagai hepatoprotektor dengan metode spektrofotometri UV-Vis', Cendekia Journal of Pharmacy, 4(2), pp. 110–119. doi: 10.31596/cjp.v4i2.89.
Sukma, N.W.P.S. & Yowani, S.C. (2023) 'Literature review: formulasi obat kumur pencegah infeksi rongga mulut berbasis nanopartikel perak ekstrak daun keji beling', Prosiding Workshop dan Seminar Nasional Farmasi, 1, pp. 101–115. doi: 10.24843/wsnf.2022.v01.i01.p08.
Sukmawati, Sudewi, S. & Pontoh, J. (2018) 'Optimasi dan validasi metode analisis dalam penentuan kandungan total flavonoid pada ekstrak daun gedi hijau (Abelmoschus manihot L.) yang diukur menggunakan spektrofotomter UV-Vis', Pharmacon Jurnal Ilmiah Farmasi-UNSRAT, 7(3), pp. 32–41. doi: 10.35799/pha.7.2018.20117.
Susanty, S. & Bachmid, F. (2016) 'Perbandingan metode ekstraksi maserasi dan refluks terhadap kadar fenolik dari ekstrak tongkol jagung (Zea mays L.)', Jurnal Konversi, 5(2), pp. 87. doi: 10.24853/konversi.5.2.87-92.
Widyaningsih, W. (2010) 'Uji aktivitas antioksidan ekstrak etanol daun dewa (Gynura procumbens) dengaln metode DPPH (1,1-difenil-2-pikrilhidralzil)', Prosiding Seminar Nasional Kosmetikal Allami, pp. 109–115.
Wijaya, Li R. & Safitri, C.I.N.H. (2020) 'Uji aktivitas formulasi lip balm dari ekstrak bekatul padi (Oryza sativa) sebagai tabir surya', Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek), 5, pp. 276–283.
Zaky, M., Pratiwi, D. & Mianah, M. (2022) 'Formulasi dan uji aktivitas antioksidan lotion ekstrak etanol 70% daun keji beling (Strobilanthes crispus L.) dengan metode DPPH', Jurnal Farmagazine, 9(1), pp. 10–19. doi: 10.47653/farm.v9i1.594.
Copyright (c) 2024 Sinta Nuraesa, Susanti Susanti, Ali Nofriyaldi
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
BIKF by Unair is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
1. The journal allows the author to hold the copyright of the article without restrictions.
2. The journal allows the author(s) to retain publishing rights without restrictions
3. The legal formal aspect of journal publication accessibility refers to Creative Commons Attribution Share-Alike (CC BY-SA).
4. The Creative Commons Attribution Share-Alike (CC BY-SA) license allows re-distribution and re-use of a licensed work on the conditions that the creator is appropriately credited and that any derivative work is made available under "the same, similar or a compatible license”. Other than the conditions mentioned above, the editorial board is not responsible for copyright violation.
