Antioxidant Activity of Stick Mask of Binahong Leaves Ethanolic Extract (Anredera cordifilia (Ten.) Steenis)
Aktivitas Antioksidan Sediaan Stick Mask Ekstrak Etanol Daun Binahong (Anredera cordifolia (Ten.) Steenis)
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The development of the cosmetic industry created many new variations of cosmetic products. One of the beauty products that was developing was a stick mask with the benefit of preventing premature aging. Binahong (A. cordifolia) leaf was one of the plants that had antioxidant activity because of flavonoids that prevent premature aging of the skin. The study aimed to make a stick mask of ethanol extract of binahong (A. cordifolia) leaf and evaluation and test the antioxidant activity using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method of the stick mask preparation. The preparation formulation was performed with variations in extract concentration at F0 0%, F1 25%, F2 30%, and F3 35%. Evaluation of the preparation includes organoleptic test, homogeneity, pH, spreadability, adhesives, dry time, and melting point test showed that the preparations met the standard requirements. The antioxidant activity of binahong (A. cordifolia) leaf ethanol extract stick mask in F3 with 35% extract concentration resulted in very strong antioxidant category with IC₅₀ 1,500 μg/mL.
Keywords: Antioxidant, Binahong leaf (Anredera cordifolia (Ten.) Steenis), DPPH (2,2-diphenyl-1-picrylhydrazyl), Mask
Agustiarini, V. and Wijaya, D.P. (2022) ‘Uji aktivitas antioksidan ekstrak etanol-air (1:1) bunga rosella (Hibiscus sabdariffa L.) dengan metode DPPH (1,1-difenil-2-pikrilhidrazil)’, Jurnal Penelitian Sains, 24(1), pp. 29.
Ayu, P., Surbakti, A., Queljoe, E.D. and Boddhi, W. (2018) ‘Skrining fitokimia dan uji toksisitas ekstrak etanol daun binahong (Andredera cordifolia (Ten.) Steenis) dengan metode Brine Shrimp Lethality Test (BSLT)’, Pharmacon: Jurnal Ilmiah Farmasi – UNSRAT, 7(3), pp. 22–31.
Cahyanta, A.N. and Ardiyanti, N.Y. (2018) ‘Uji aktivitas salep anti jerawat ekstrak etanol daun binahong (Anredera cordifolia (Ten.) Steenis) terhadap bakteri Propionibacterium acnes’, Parapemikir: Jurnal Ilmiah Farmasi, 7(2), pp. 239.
Cahyono, B., Prihatini, C.S., Suzery, M. and Bima, D.N. (2021) ‘Penentuan aktivitas antioksidan senyawa kuersetin dan ekstrak lengkuas menggunakan HPLC dan UV-Vis’, Alchemy, 8(2), pp. 24–32.
Cholvistaria, M., Widowati, H. and Sutanto, A. (2021) ‘Hubungan penurunan vitamin C sayuran hiperkumulator dengan residu zat aktif insektisida fipronil’, Jurnal Penelitian Pertanian Terapan, 21(3), pp. 242–250.
Devitria, R., Sepriyani, H. and Sari, S. (2020) ‘Uji aktivitas antioksidan ekstrak metanol daun ciplukan menggunakan metode 2,2-diphenyl 1-picrylhydrazyl (DPPH)’, Jurnal Penelitian Farmasi Indonesia, 9(1), pp. 31–36.
Fauziah, F., Alvanny, N. and Andalia, K. (2022) ‘Formulasi evaluasi masker clay dari ekstrak etanol daun pepaya (Carica papaya L.) sebagai anti jerawat’, Jurnal Riset Kefarmasian Indonesia, 4(3), pp. 306–320.
Fitriani, N., Herman and Laode, R. (2019) ‘Antioksidan ekstrak daun sumpit (Brucea javanica (L.) Merr) dengan metode DPPH’, Jurnal Sains dan Kesehatan, 2(1), pp. 57–62.
Ginting, O.S.B., Rambe, R., Athaillah, A. and Mahara, P.H.S. (2021) ‘Formulasi sediaan sampo anti ketombe ekstrak daun binahong (Anredera cordifolia (Tenore) Steen) terhadap aktivitas jamur Candida albicans secara in vitro’, Forte Journal, 1(1), pp. 57–68.
Iskandar, B., Ernilawati, M., Firmansyah, F. and Frimayanti, N. (2021) ‘Formulasi blush on stick dengan zat pewarna alami ekstrak kering buah naga merah (Hylocereus polyrhizus L.)’, Cendekia Journal of Pharmacy, 5(1), pp. 70–80.
Iskandar, B., Tartilla, R., Lukman, A., Leny, L. and Surboyo, M.D.C. (2022) ‘Uji aktivitas anti-aging mikroemulsi minyak nilam (Pogostemon cablin Benth.)’, Majalah Farmasetika, 7(1), pp. 52.
Islamiah, N.F., Sukrasno and Simanullang, G. (2023) ‘Formulasi dan evaluasi stabilitas fisik sediaan lip balm minyak bekatul (Rice Bran Oil)’, Media Farmasi Indonesia, 18(2), pp. 124–135.
Ningsih, W.P., Widiastuti, R. and Eltivitasari, A. (2023) ‘Formulasi dan uji karakteristik fisik sediaan masker clay serbuk biji kopi robusta (Coffea robusta)’, Sinteza, 3(1), pp. 1–8.
Noviyanty, Y., Harlina, H. and Adha, A.Y. (2022) ‘Pengaruh metode ekstraksi terhadap kadar flavonoid ekstrak etanol daun binahong (Anredera cordifolia (Ten.)) dengan metode spektrofotometri UV-VIS’, Oceana Biomedicina Journal, 5(2), pp. 93–106.
Oktavia, F.D. and Sutoyo, S. (2021) ‘Skrining fitokimia, kandungan flavonoid total, dan aktivitas antioksidan ekstrak etanol tumbuhan Selaginella doederleinii’, Jurnal Kimia Riset, 6(2), pp. 141.
Pangaribuan, L. (2017) ‘Efek samping kosmetik dan penangananya bagi kaum perempuan’, Jurnal Keluarga Sehat Sejahtera, 15(2), pp. 20–28.
Parwati, N.K.F., Napitupulu, M. and Diah, A.W.M. (2014) ‘Uji aktivitas antioksidan ekstrak daun binahong (Anredera cordifolia (Tenore) Steenis) dengan 1,1-difenil-2-pikrilhidrazil (DPPH) menggunakan spektrofotometer UV-VIS’, Jurnal Akademika Kimia, 3(4), pp. 206–213.
Purnadirani, A., Mutmainah, Kristantri, R.S., Sari, W.K. and Pebriani, T.H. (2024) ‘Formulasi masker clay ekstrak metanol daun jarong (Achyranthes aspera L.) dan uji aktivitas antioksidan dengan metode DPPH’, Jurnal Ilmiah Farmasi, 13(1), pp. 91–97.
Sari, D.J., Wilujeng, B.Y., Lutfiati, D. and Dwiyanti, S. (2020) ‘Masker perawatan kulit wajah berbahan wortel (Daucus carota)’, e-Jurnal, 9(4), pp. 65–71.
Septyowardani, D.T. and Parmadi, A. (2021) ‘Formulasi krim tabir surya dan penentuan nilai SPF ekstrak etanol daun binahong (Anredera cordifolia (Tenore) Steenis)’, Indonesian Journal on Medical Science, 8(2), pp. 2–8.
Susiloningrum, D. and Sari, M.D.E. (2021) ‘Uji aktivitas antioksidan dan penetapan kadar flavonoid total ekstrak temu mangga (Curcuma mangga Valeton & Zijp) dengan variasi konsentrasi pelarut’, Cendekia Journal of Pharmacy, 5(2), pp. 117–127.
Utami, H.F., Hastuti, R.B., Hastuti, D. and Biologi, J. (2015) ‘Kualitas daun binahong (Anredera cordifolia) pada suhu pengeringan berbeda’, Jurnal Biologi, 4(2), pp. 51–59.
Wahyuni, Saputri, R.K. and Hutahaen, T.A. (2023) ‘Uji antioksidan dan efektivitas sediaan toner ekstrak daun binahong merah (Anredera cordifolia)’, Indonesian Journal of Health Science, 3(2a), pp. 438–445.
Warnida, H., Wahyuni, D. and Sukawaty, Y. (2019) ‘Formulasi dan evaluasi vanishing cream berbasis lemak tengkawang’, Jurnal Penelitian Ekosistem Dipterokarpa, 5(1), pp. 63–70.
Yang, R.Y., Lin, S. and Kuo, G. (2008) ‘Content and distribution of flavonoids among 91 edible plant species’, Asia Pacific Journal of Clinical Nutrition, 17(Suppl. 1), pp. 275–279.
Yani, T.N., Anwar, E. and Saputri, F.C. (2017) ‘Formulasi emulgel yang mengandung ekstrak etanol daun binahong (Anredera cordifolia (Ten.) Steenis) dan uji aktivitasnya terhadap Propionibacterium acnes secara in vitro’, Jurnal Kefarmasian Indonesia, 6(2), pp. 89–97.
Yuniarsih, N., Indriyati, A. and Munjiani, A. (2021) ‘Review: masker wajah herbal di Indonesia’, Jurnal Buana Farma, 1(1), pp. 17–21.
Yunita, E. and Khodijah, Z. (2020) ‘Pengaruh konsentrasi pelarut etanol saat maserasi terhadap kadar kuersetin ekstrak daun asam jawa (Tamarindus indica L.) secara spektrofotometri UV-Vis’, Pharmacy: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia), 17(2), pp. 273.
Zaini, M., Hidriya, H. and Japeri, J. (2020) ‘Aktivitas antioksidan ekstrak etanol Muntingia calabura dengan variasi laju pengadukan menggunakan macerator-magnetic stirrer (M-MS)’, Jurnal Pharmascience, 7(2), pp. 27.
Zulfa, E., Lailatunnida, L. and Murukmihadi, M. (2018) ‘Formulasi sediaan krim daun binahong (Anredera cordifolia (Ten.) Steenis): kajian karakteristik fisika kimia dan uji iritasi kulit’, Jurnal Inovasi Teknik Kimia, 3(1), pp. 46–52.
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