The correlation between serum TG/HDL-c ratio and arterial stiffness using the cardio-ankle vascular index in overweight or obese patients
Versions
- 2020-09-19 (2)
- 2020-09-19 (1)
Downloads
The effect of increasing TG/HDL-c serum ratio, as a result of insulin resistance, is considered to have an important role in the occurrence of arterial stiffness. Increased arterial stiffness is an important marker in the development of cardiovascular disease and is a predictor of heart attack and stroke. This research aims to determine the relationship between the arterial stiffness assessed through non-invasive cardio-ankle vascular index (CAVI) examination and the TG/HDL-c ratio in overweight and obese individuals. Cardio-Ankle Vascular Index (CAVI) is a non-invasive clinical measurement to evaluate arterial stiffness manner and independent of blood pressure. This is a correlational study with purposive sampling technique. Thirty-two subjects participated in this research and each subject underwent a CAVI examination to assess arterial stiffness and their blood samples were collected for lipid profile measurement. The data were analysed using Pearson Correlation Test. There was a positive and significant correlation between TG/HDL-c serum level and arterial stiffness using Cardio- Ankle Vascular Index (CAVI) in overweight or obese patients (p <0,01).
Brillante DG, O'Sullivan AJ, and Howes LG. Arterial Stiffness in Insulin Resistance: The Role of Nitric Oxide and Angiotensin II Receptors. Vasc Health Risk Manag; 2009. 5: 73–8.
Villacorta L, and Chang DL. The Role of Perivascular Adipose tissue in Vasoconstriction, Arterial Stiffness, and Aneurysm. Horm Mol Biol Clin Investig; 2015. 21: 137.
DiBonito P, et al. Usefulness of The High Triglyceride-to-HDL Cholesterol Ratio to Identify Cardiometabolic Risk Factors and Preclinical Signs of Organ Damage in Outpatient Children. Diabetes Care; 2012. 35: 158–62.
Wang F, Ye P, Luo L, Xiao W, Qi L, Bian S, Wu H, Sheng L, Xiao T, and Xu R. Association of Serum Lipids with Arterial Stiffness in a Population-based Study in Beijing. Eur J Clin Invest; 2011. 41: 929–36.
Gaziano JM, Hennekens CH, O'Donnell CJ, Breslow JL, and Buring JE. Fasting Triglycerides, High-density Lipoprotein, and Risk of Myocardial Infarction. Circulation; 1997. 96: 2520–5.
Diraison F, Moulin P, and Beylot M. Contribution of Hepatic de Novo Lipogenesis and Re-esterification of Plasma Non Esterified Fatty Acids to Plasma Triglyceride Synthesis during Non-alcoholic Fatty Liver Disease. Diabetes Metab; 2003. 29: 478–85
Schwarz J-M, Linfoot P, Dare D, and Aghajanian K. Hepatic de Novo Lipogenesis in Normoinsulinemic and Hyperinsulinemic Subjects Consuming High-fat, Low-carbohydrate and Low-fat, High-carbohydrate Isoenergetic Diets. Am J Clin Nutr; 2003. 77: 43–50.
Grundy SM. Small LDL, Atherogenic Dyslipidemia, and the Metabolic Syndrome Circulation; 1997. 95: 1–4.
LauceviÄius A, RyliÅ¡kyte L, Balsyte J, Badariene J, Puronaite R, Navickas R, and Solovjova S. Association of Cardio-Ankle Vascular index with Cardiovascular Risk Factors and Cardiovascular Events in Metabolic Syndrome Patients. Med; 2015. 51: 152–8.
Luo K-Q, Feng X-W, Xu B-C, and Long H-B. Association Between Arterial Stiffness and Risk of Coronary Artery Disease. Pakistan J Med Sci; 2014. 30: 1314–8.
Kotani K. Cardio-Ankle Vascular Index and Its Potential Clinical Implications for Sleep Apnea Pulse (Basel, Switzerland). 2014. 1: 139–42.
McLaughlin T, Abbasi F, Cheal K, Chu J, Lamendola C, and Reaven G. Use of Metabolic markers to identify overweight individuals who are insulin resistant. Ann Intern Med; 2003. 139: 802–9.
Nagayama D, et al. Effects of Body Weight Reduction on Cardio-Ankle Vascular Index (CAVI). Obes Res Clin Pract; 2013. 7: e139–45
- Cardiovascular and Cardiometabolic Journal (CCJ) is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License
-
Authors who publish with Cardiovascular and Cardiometabolic Journal (CCJ) agree to the following terms:
-
The journal allows the author to hold the copyright of the article without restrictions.
-
The journal allows the author(s) to retain publishing rights without restrictions.
-
The legal formal aspect of journal publication accessibility refers to Creative Commons Attribution ShareAlike 4.0 International License (CC BY-SA).