Correlation Between Oral Contraceptives Use and Sexual Activity with Cervical Cancer
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The World Health Organization in 2012 showed that of the total new cases of cervical cancer in the world, 85% of cases were found in developing countries. In 2015, Malang City and Malang District were alert for cervical cancer. This study aims to analyze the relationship between risk factors for use of oral contraceptives and sexual activity with the incidence of cervical cancer in patients in the Obstetrics and Gynecology Clinic of the Regional Public Hospital (RSUD) Dr. Saiful Anwar Malang. This study uses a case-control design. The study population was poly obstetrics and gynecology outpatients Dr. Saiful Anwar Malang in November 2015. Case samples were 37 cervical cancer patients and 111 control samples were non-cervical cancer patients. Sampling using systematic random sampling. Data analysis using the Chi-square test. The independent variables studied were the use of oral contraceptives and sexual activity which included the age of first sexual intercourse <18 years, the age of first pregnancy <18 years, and a history of abortion. Primary data collection uses interviews while secondary uses the patient's medical record. The results showed there was a relationship between the age of first sexual intercourse <18 years (p = 0.0225147014; OR = 2.3194; 95% CI = 1.0854–4.9561), age of first pregnancy <18 years (p = 0.0236276656; OR = 2.33388; 95% CI 1.0890-5.0230), and history of abortion (p = 0.0038911219; OR = 3.2653; 95% CI = 1.4593–7.3063) with cervical cancer. The conclusion of this study is the age of first sexual intercourse, age at first pregnancy and abortion are risk factors for cervical cancer.
Alliance for Cervical Cancer Prevention. 2004. Risk Factors for Cervical Cancer: Evidence to Date, Washington: Alliance for Cervical Cancer Prevention.
Andrews, G. 2010. Women's Sexual Health. 2nd Edition ed. Jakarta: EGC.
Dewi, N.K., Rejeki, S. & Istiana, S. 2014. Hubungan Lama Penggunaan Kontrasepsi Oral pada Wanita Usia Lebih dari 35 Tahun dengan Stadium Kanker Serviks di RSUD Kota Semarang. Jurnal Kebidanan Unimus. 4(1), pp. 31–38.
Dong, P.D., Lin, R.S. & Royal, J. 1995. Induced Abortion in Taiwan. Social Health, 115(2) pp. 100–108.
Goldman, M. B., Troisi, R. & Rexrode, K. M. 2013. Women & Health 2nd Edition. London: Academic Press.
Guttmacher Institute. 2002. Long-Term Pill Use, High Parity Raise Cervical Cancer Risk Among Women with Human Papillomavirus Infection. International Family Planning Perspectives, 28(3), pp. 176–181.
Ibflet, E., Kjaer, S. K., Johansen, C., Hogdal, C., Jessen, M.S., Frederiksen, K., Frederiksen, B.L., Osler, M. & Dalton, S.O. 2012. Socioeconomic Position and Stage of Cervical Cancer in Danish Woman Diagnosed 2005 to 2009. American Association for Cancer Research, Volume 21, pp. 835–842.
Kemenkes RI. 2010. Buku Acuan Pencegahan Kanker Leher Rahim dan Kanker Payudara. Jakarta: Dinas Kesehatan Provinsi Jawa Timur Seksi P3PMK Tahun Anggaran 2012.
Kuie, T.S. 2009. Cervical Cancer its Causes and Prevention. Singapore: Marshall Cavendish Editions.
Lestari, S. 2012. Hubungan Tingkat Pendidikan, Pengetahuan dan Sikap Ibu Rumah Tangga dengan Perilaku Deteksi Dini Kanker Serviks Metode IVA di Puskesmas Jaten II Kabupaten Karanganyar. Thesis. Surakarta: Universitas Sebelas Maret.
Makuza, J.D., Nsanzimana, S. Muhimpundu, M.A., Pace, L.E., Ntaganira, J. & Riedel, D.J. 2015. Prevalence and Risk Factors for Cervical Cancer abd Pre-cancerous lesions in Rwanda. The Pan African Medical Journal, Volume 23, pp. 22–26.
Merrill, R.M. 2010. Reproductive Epidemiology Principle and Methods. Canada: Jones and Bartlett Publishers.
Paramita, S., Soetomo, S., Widodo, M.A. & Sumitro, S.B. 2010. High Parity and Hormonal Contraception Use as Risk Factors for Cervical Cancer in East Kalimantan. Medical Journal of Indonesia, 19(4), pp. 268–72.
Pusat Data dan Informasi. 2014. Situasi dan Analisis Keluarga Berencana, Jakarta Selatan: s.n.
Rasjidi, I. 2010. 100 Questions & Answer Kanker pada Wanita. Jakarta: PT Elex Media Komputindo.
Republika. 2013. Ratusan Perempuan di Malang Menderita Kanker Serviks. [Online] Available at: http://www.republika.co.id/berita/nasional/ jawa-timur/13/12/22/my7tcq-ratusan-perempuan-di-malang-menderita-kanker-serviks [Accessed 14 Maret 2015].
Robboy, S.J., Mutter, G.L., Prat, J., Bentley, R.C., Russell, P. & Anderson, M.C. 2009. Pathology of the Female Reproductive Tract. 2nd ed. British: Churchill Livingstone Elsevier.
Saifuddin, A.B. Affandi, B., Baharuddin, M. & Soekir, S., 2010. Buku Panduan Praktis Pelayanan Kontrasepsi. 2 ed. Jakarta: PT. Bina Pustaka Sarwono Prawirohardjo.
Sastrawinata, S., Martaadisoebrata, D. & Wirakusumah, F. 2004. Ilmu Kesehatan Reproduksi: Obstetri Patologi. 2 ed. Jakarta: EGC.
Satyarini, S. 2011. Faktor Risiko Kanker Serviks di Rumah Sakit Umum Pemerintah Dr. Wahidin Sudirohusodo Makassar, Sulawesi Selatan. Jurnal Kesehatan Masyarakat Nasional, 5(6), pp. 283–288.
Shields, T.S., Brinton, L.A., Burk, R.D., Wang, S.S., Weinstein, S.J., Ziegler, R.G., Studentsov, Y.Y., McAdams, M. & Schiffman, M. 2004. A Case-Control Study of Risk Factors for Invasive Cervical Cancer among U.S. Women Exposed to Oncogenic Types of Human Papillomavirus. Cancer Epidemiol Biomarker, 13(10), pp. 1574–1582.
Supranto, J. 2007. Statistik untuk Pemimpin Berwawasan Global. 2 ed. Jakarta: Salemba Empat.
Surya. 2015. Jatim Darurat Kanker Serviks, Ini Tujuh Daerah di Jatim Yang Masuk Peta Waspada Kanker Serviks. [Online] Available at: http:// surabaya.tribunnews.com/2015/03/09/ini-tujuh-daerah-di-jatim-yang-masuk-peta-waspada-kanker-serviks [Accessed 7 Juli 2015].
Urban, M., Banks, E., Egger, S., Canfell, K., O'Connell, D., Beral, V. & Sitas, F. 2012. Injectable and Oral Contraceptive Use and Cancers of the Breast, Cervix, Ovary, and Endometrium in Black South African Women: Case–Control Study. PLos Med, 9(3), pp. 1–11.
Vaisy, A., Lotfinejad, S. & Zhian, F. 2014. Risk of Cancer with Combined Oral Contraceptive Use among. Asian Pac J Cancer Prev, 15(14), pp. 5517–5522.
Vecchia, L., Carlo, Boccia & Stefania. 2014. Oral Contraceptives, Human Papillomavirus and Cervical Cancer. European Journal of Cancer Prevention, 23(2), pp. 110–112.
WHO. 2014. Comprehensive Cervical Cancer Control: a Guide to Essential Practice Second Edition. Switzerland: WHO Press.
Winship Cancer Institute of Emory University. 2014. Cervical Cancer: Risk Factors. [Online] Available at: http://www.cancerquest.org/cervical-cancer-risks.html [Accessed 22 Maret 2015].
Wisconsin Cancer Data Bulletin. 2014. Cervical Cancer in Wisconsin. Wisconsin: Wisconsin Cancer Reporting System.
Wulandari, V. 2016. Hubungan Paritas, Usia Pertama Kali Berhubungan Seksual dan Penggunaan Kontrasepsi Oral dengan Kejadian Kanker Serviks (Studi di Poli Obstetri dan Ginekologi RSUD Dr. Saiful Anwar Malang). Skripsi. Surabaya: Universitas Airlangga.
Yuniar, I., Saryono & Rohani, F. 2009. Faktor-faktor yang memengaruhi kejadian kanker serviks di Puskesmas Karanganyar. Jurnal Ilmiah Kesehatan Keperawatan, 5(2) pp. 109–118.
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