RISK FACTORS OF DENGUE MORTALITY IN PAMEKASAN DISTRICT (2018-2020)
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Background: The incidence of Dengue Haemoragic Fever (DHF) in the Pamekasan District is still high. Mortality of DHF was always happening in Pamekasan District from 2016 to 2020. Purpose: This study aims to analyze the risk factors of DHF mortality in the Pamekasan District (2018-2020). Methods: The study was conducted from October 2020-June 2021 with a case-control study. Total population was 293 cases. The sample was 54 respondents (1:2) with proportional random sampling. The inclusion criteria were families living under the same roof for a minimum of 17 years. The variables were dengue mortality, age, sex, education, history of DHF, comorbidities, access to health services, delay in treatment, family income, residence, and family knowledge. Data were collected through interviews and documentation study. The analysis in this study used univariate (frequency) and bivariate (crosstabs use OR). Results: Risk factors of DHF mortality in Pamekasan District are children (OR = 2.05; 95% CI=0.59-7.04), low education (OR=1.16; 95% CI=0.30-4.46), history of dengue (OR=3.57;95%CI=1.09-11.66), comorbidities(OR=17.50; 95% CI=4.25-72.05), difficult access to health services (OR=3.10; 95% CI=0.79-12.09), delay in treatment (OR=5.20;95% CI=1.50-18.0), low income family (OR=1.16; 95% CI = 0.30-4.46) and low of family knowledge about dengue (OR = 7.00; 95% CI = 1.99-24.58). Meanwhile, protective factors are female (OR = 0.70; 95% CI = 0.22-2.23) and rural (OR = 0.48 ; 95% CI = 0.13-1.73). Conclusion: Risk factors of DHF mortality in Pamekasan District (2018-2020) are the history of DHF, comorbidities, delay in treatment, and low family knowledge about DHF.
ABSTRACT
Background: The incidence of dengue fever in Pamekasan District is still high. Mortality of dengue was always happen in Pamekasan District since 2016 to 2020. Purpose: This study aimed to analyze the risk factors of dengue mortality in Pamekasan District (2018-2020). Methods: This research was case-control study. The study was conducted from October 2020-June 2021 in Primary Health Care selected at Pamekasan District. Total sample was 54 cases. Data was collected by interviews and documentation study. Analysis using uinvariate and bivariate (OR test). Results: Based on the results of OR test, risk factors of dengue mortality in pamekasan district (2018-2020) are: children (OR = 2.05 ; 95% CI = 0.59-7.04), education ≤ 9 yeras (OR = 1.16; 95% CI= 0.30-4.46), history of dengue (OR= 3.57 ; 95% CI = 1.09-11.66), comorbidities (OR=17.50; 95% CI=4.25-72.05), difficult access to health services (OR=3.10; 95% CI=0.79-12.09), delay in treatment (OR=5.20 ; 95% CI = 1.50-18.0), low income family (OR = 1.16; 95% CI = 0.30-4.46) and low of family knowledge about dengue (OR = 7.00; 95% CI = 1.99-24.58) while protective factors are : female (OR = 0.70; 95% CI = 0.22-2.23) and rural areas (OR = 0.48 ; 95% CI = 0.13-1.73). Conclusion: Risk factors of dengue mortality in Pamekasan District (2018-2020) are history of dengue, comorbidities, delay in treatment and low of family knowledge about dengue.
Arhana, B. N. P. (2016). Rasio IgM/IgG fase akut untuk menentukan infeksi dengue sekunder. Sari Pediatri, 8(1), 2. https://doi.org/10.14238/sp8.1.2006.2-8
Aryati, Wardhani, P., Rochaeni, A., Akualing, S., & Hadi, U. (2017). Anti dengue IgG/IgM ratio for secondary adult dengue infection in Surabaya. Indonesian Journal of Clinical Pathology Abd Medical Laboratory, 24(1), 81–85. https://doi.org/10.24293/ijcpml.v24i1.1161
Cáceres Munar, B. A., Castellanos Parra, J. E., & Rodríguez Panduro, M. H. (2019). Antibody-dependent enhancement in the immunopathogenesis of severe dengue, implications for the development and use of vaccines. Acta Biologica Colombiana, 24(3). https://doi.org/10.15446/abc.v24n3.79410
Casas, I., Delmelle, E., & Delmelle, E. C. (2017). Potential versus revealed access to care during a dengue fever outbreak. Journal of Transport and Health, 4, 18–29. https://doi.org/10.1016/j.jth.2016.08.001
Dinas Kesehatan Provinsi Jawa Timur. (2020). Profil kesehatan Provinsi Jawa Timur. Jawa Timur: Dinas Kesehatan Provinsi Jawa Timur. Retrieved from https://dinkes.jatimprov.go.id/userfile/dokumen/PROFIL KESEHATAN 2020.pdf
Dinkes Pamekasan. (2020). Data kejadian demam berdarah Kabupaten Pamekasan tahun 2018- 2020. Pamekasan: Dinas Kesehatan Kabupaten Pamekasan.
Hegazi, M. A., Bakarman, M. A., Alahmadi, T. S., Butt, N. S., Alqahtani, A. M., Aljedaani, B. S., & Almajnuni, A. H. (2020). Risk factors and predictors of severe dengue in Saudi population in Jeddah, western Saudi Arabia: a retrospective study. American Journal of Tropical Medicine and Hygiene, 102(3), 613–621. https://doi.org/10.4269/ajtmh.19-0650
Hikmah, M., & H, O. W. K. (2015). Faktor yang berhubungan dengan kejadian kematian akibat demam berdarah dengue. Unnes Journal of Public Health, 4(4). Retrieved from https://journal.unnes.ac.id/sju/index.php/ujph/article/view/9693
Idris, R., Tjeng, W. S., & Sudarso, S. (2017). Hubungan antara hasil pemeriksaan Leukosit, Trombosit dan Hematokrit dengan derajat klinik DBD pada pasien anak Di RSUD Abdul Wahab Sjahranie Samarinda. Sari Pediatri, 19(1), 41. https://doi.org/10.14238/sp19.1.2017.41-5
Khetarpal, N., & Khanna, I. (2016). Dengue fever: causes, complications, and vaccine strategies. Journal of Immunology Research, 2016(3). https://doi.org/https://doi.org/10.1155/2016/6803098
Laksono, A. D., Mubasyiroh, R., Laksmiarti, T., Nurhotimah, E., Suharmiati, & Sukoco, N. E. (2016). Aksesibilitas pelayanan kesehatan di Indonesia. Yogyakarta: PT.Kanasius.
Lestari, K. D. (2018). Faktor risiko kejadian dengue shock syndrome pada pasien demam berdarah dengue di RSUP Sanglah Denpasar Tahun 2015. Medicina, 49(3), 320–324. https://doi.org/10.15562/medicina.v49i3.383
Liew, S. M., Khoo, E. M., Ho, B. K., Lee, Y. K., Omar, M., Ayadurai, V., ... Chinna, K. (2016). Dengue in Malaysia: factors associated with dengue mortality from a national registry. PLoS ONE, 11(6), 1–14. https://doi.org/10.1371/journal.pone.0157631
Linn, N. N., Kyaw, K. W. Y., Shewade, H. D., Kyaw, A. M. M., Tun, M. M., Khine, S. K., ... Lin, Z. (2020). Notified dengue deaths in Myanmar (2017-18): profile and diagnosis delays. F1000Research, 9, 1–14. https://doi.org/10.12688/f1000research.23699.1
Macias, A. E., Werneck, G. L., Castro, R., Mascareñas, C., Coudeville, L., Morley, D., ... Toh, M. L. (2021). Mortality among hospitalized dengue patients with comorbidities in Mexico, Brazil, and Colombia. American Journal of Tropical Medicine and Hygiene, 105(1), 102–109. https://doi.org/10.4269/ajtmh.20-1163
Mallhi, T. H., Khan, A. H., Sarriff, A., Adnan, A. S., & Khan, Y. H. (2017). Determinants of mortality and prolonged hospital stay among dengue patients attending tertiary care hospital: a cross-sectional retrospective analysis. BMJ Open, 7(7), 1–12. https://doi.org/10.1136/bmjopen-2017-016805
Mehta, P., & Hotez, P. J. (2016). NTD and NCD Co-morbidities: The example of dengue fever. PLoS Neglected Tropical Diseases, 10(8), 3–7. https://doi.org/10.1371/journal.pntd.0004619
Naeem, S., Pari, A., Gulzar, N., Yousaf, S., & Akhtar, M. S. (2018). Mortality rate of patients with dengue hemorrhagic fever. Pakistan Journal of Medical and Health Sciences, 12(1), 337–339.
Napirah, M. R., Rahman, A., & Tony, A. (2016). Faktor-faktor yang berhubungan dengan pemanfaatan pelayanan kesehatan di wilayah kerja Puskesmas Tambarana Kecamatan Poso Pesisir Utara Kabupaten Poso. Jurnal Pengembangan Kota, 4(1), 29. https://doi.org/10.14710/jpk.4.1.29-39
Nunes, P. C. G., Daumas, R. P., Sánchez-Arcila, J. C., Nogueira, R. M. R., Horta, M. A. P., & Dos Santos, F. B. (2019). 30 years of fatal dengue cases in Brazil: a review. BMC Public Health, 19(1), 1–11. https://doi.org/10.1186/s12889-019-6641-4
Permata, A. C. (2021). Hubungan persepsi orang tua tentang kegawatan demam berdarah dengue dengan tindakan penanganan awal demam berdarah dengue pada anak di rumah di wilayah kerja puskesmas Jenggawah Jember (Universitas Jember). Universitas Jember. Retrieved from https://repository.unej.ac.id/bitstream/handle/123456789/103805/Aisyah Chitra Permata - 162310101248 Sdh.pdf?sequence=1&isAllowed=y
Trisasri, R., Arguni, E., & Ahmad, R. A. (2017). Faktor risiko kematian akibat dengue di RSUP Dr. Sardjito Yogyakarta (Universitas Gadjah Mada). Universitas Gadjah Mada. Retrieved from https://pdfs.semanticscholar.org/b55b/f3fd968742d2cb999923e9e04665fe3c0b08.pdf
Usman, H. B., AlSahafi, A., Abdulrashid, O., Mandoura, N., Al Sharif, K., Ibrahim, A., ... Shamia, M. (2018). Effect of health education on dengue fever: A comparison of knowledge, attitude, and practices in public and private high school children of Jeddah. Cureus, 10(12), 6–13. https://doi.org/10.7759/cureus.3809
Wei, H. Y., Shu, P. Y., & Hung, M. N. (2016). Characteristics and risk factors for fatality in patients with dengue Hemorrhagic Fever, Taiwan, 2014. American Journal of Tropical Medicine and Hygiene, 95(2), 322–327. https://doi.org/10.4269/ajtmh.15-0905
Werneck, G. L., Macias, A. E., Mascarenas, C., Coudeville, L., Morley, D., Recamier, V., ... Toh, M. L. (2018). Comorbidities increase in-hospital mortality in dengue patients in Brazil. Memorias Do Instituto Oswaldo Cruz, 113(8), 1–5. https://doi.org/10.1590/0074-02760180082
WHO. (2019). Dengue and severe dengue. World Health Organization. Regional Office for the Eastern Mediterranean. Retrieved from World Health Organization. Regional Office for the Eastern Mediterranean website: https://www.who.int/news-room/facts-in-pictures/detail/dengue-and-severe-dengue
Woon, Y. L., Hor, C. P., Hussin, N., Zakaria, A., Goh, P. P., & Cheah, W. K. (2016). A two-year review on epidemiology and clinical characteristics of dengue deaths in Malaysia, 2013-2014. PLoS Neglected Tropical Diseases, 10(5), 2013–2014. https://doi.org/10.1371/journal.pntd.0004575
Yu, H. R., Tsai, J. H., Richard Lin, C. H., Wang, J. Y., Wen, Y. H., Wu, S. S., ... Lee, Y. C. (2019). Is asthma a protective factor for dengue fever? in vitro experiment and nationwide population-based cohort analysis. Allergology International, 68(4), 486–493. https://doi.org/10.1016/j.alit.2019.06.001
Zajacova, A., & Lawrence, E. M. (2018). The relationship between education and health: reducing disparities through a contextual approach. Annual Review of Public Health, 39, 273–289. https://doi.org/10.1146/annurev-publhealth-031816-044628
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