THE EFFECT OF COMORBIDITIES ON MORTALITY IN COVID-19 PATIENTS IN dr RADEN SOEDARSONO HOSPITAL PASURUAN
Pengaruh Komorbid Terhadap Mortalitas Pada Pasien COVID-19 yang di RSUD dr. Raden Soedarsono Kota Pasuruan
Downloads
Background: COVID-19 patients with comorbidities have the highest mortality risk in Indonesia during the pandemic. Purpose: This study purposed to determine the prevalence of comorbidities on mortality of COVID-19 patients at RSUD dr. Raden Soedarsono, Pasuruan. Methods: This study used a case-control design with 560 samples collected from January until December 2021. The samples consisted of 140 COVID-19 patients who were treated at RSUD dr. Raden Soedarsono, Pasuruan, in 2021 and declared dead as a case group, as well as 420 COVID-19 patients treated at RSUD dr. Raden Soedarsono, Pasuruan, in 2021 but did not die as a control group. The data were then analyzed using a logistic regression test with SPSS 22.0. Results: The results show that almost all COVID-19 patients did not have comorbidities of diabetes mellitus (85.50%), autoimmune (98.60%), kidney disease (98.20%), gastrointestinal diseases (92.10%), thrombosis and coagulation disorders (93.60%), myocardial injury (99.30%), heart failure (94.30%), hypertension (95.20%), and tuberculosis (5.70%). Also, almost all COVID-19 patients did not have comorbidities of geriatrics (71.60%), COPD (64.10%), and mortality status (25.00%). The results of the logistic regression test show that comorbidities of diabetes mellitus (P-value 0.01; OR 1.99) and geriatrics (P-value 0.00; OR 2.82) affect mortality in COVID-19 patients. Whereas comorbidities of autoimmune (P-value 0.84), kidney disease (P-value 0.37), gastrointestinal diseases (P-value 0.73), thrombosis and coagulation disorders (P-value 0.24), myocardial injury (P-value 0.84), heart failure (P-value 0.43), hypertension (P-value 0.93), COPD (P-value 0.86), and tuberculosis (P-value 0.15) do not affect mortality inCOVID-19 patients. Conclusion: Diabetes Mellitus and geriatrics are the most significant comorbidities in causing the death of COVID-19 patients at RSUD dr. Raden Soedarsono, Pasuruan.
Chow N, Felming-Dutra K, Gierke R, Hall A, Hughes M, Pilishvili T, et al. Preliminary estimates of the prevalence of selected underlying health conditions among patients with Corona virus disease 2019 - United States, February 12-March 28, 2020. Morb Mortal Wkly Rep [Internet]. 2020;69(13):382–6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/32240123
Budiman D, Chu C. A SWOT Analysis of Indonesia’s COVID-19 Pandemic Response Strategy. Int J Adv Heal Sci Technol. 2021 Dec;1(2):50–2.
Ernawati T, Nugroho N, Novita BD, Tahalele PL, Darmadi ET, Hendrawan KA, et al. Covid-19 Patients’ Characteristic in Covid-19 Refferral Hospital, Surabaya, Indonesia. J Berk Epidemiol. 2022;10(1):48–57.
Hu Y, Sun J, Dai Z, Deng H, Li X, Huang Q, et al. Prevalence and severity of corona virus disease 2019 (COVID-19): A systematic review and meta-analysis. J Clin Virol Off Publ Pan Am Soc Clin Virol. 2020 Jun;127:104371.
WHO. Coronavirus Disease (COVID-19) Situation Reports [Internet]. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports
Arifin. Pasuruan Zona Merah COVID-19, Angka Kematian Capai 11,32%. Muhajir. 2020.
Drew C, Adisasmita AC. Gejala dan komorbid yang memengaruhi mortalitas pasien positif COVID-19 di Jakarta Timur , Maret-September 2020. Tarumanagara Med J [Internet]. 2021;3(2):274–83. Available from: https://journal.untar.ac.id/index.php/tmj/article/view/11742
Kementerian Kesehatan Republik Indonesia. Profil kesehatan Indonesia tahun 2019. Jakarta: Kementerian Kesehatan RI; 2020. 497 p.
Rahayu LAD, Admiyanti JC, Khalda YI, Ahda FR, Agistany NFF, Setiawati S, et al. Hipertensi, diabetes mellitus, dan obesitas sebagai faktor komorbiditas utama terhadap mortalitas pasien COVID-19: sebuah studi literatur. JIMKI J Ilm Mhs Kedokt Indones. 6376 Jul;9(1):90–7.
Nadzifah YN, Hidajah AC. The relationship of diabetes mellitus and hypertension with mortality in COVID-19 patients. J Berk Epidemiol [Internet]. 2022;10(2):219–26. Available from: https://e-journal.unair.ac.id/JBE/article/view/26489/21198
Shang J, Wang Q, Zhang H, Wang X, Wan J, Yan Y, et al. The relationship between diabetes mellitus and COVID-19 prognosis: a retrospective cohort study in Wuhan, China. Am J Med. 2021;134(1):e6–14.
Iijima K, Arai H, Akishita M, Endo T, Ogasawara K, Kashihara N, et al. Toward the development of a vibrant, super‐aged society: The future of medicine and society in Japan. Geriatr Gerontol Int. 2021;21(8):601–13.
Adetuyi BO, Adebayo PF, Olajide PA, Atanda OO, Oloke JK. Involvement of free radicals in the ageing of cutaneous membrane. World News Nat Sci. 2022;43:11–37.
Wang Y, Wang Y, Chen Y, Qin Q. Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID‐19) implicate special control measures. J Med Virol. 2020;92(6):568–76.
D.M.A. D, N.L. U, N.K.N.S. W, R. N, K.D. K. Angka kejadian penyakit autoimun pada pasien anak di RSUP Sanglah Denpasar. J Farm Udayana; Vol 5 No 2 Tahun 2016. 2017;
Aisyah DN, Mayadewi CA, Diva H, Kozlakidis Z, Siswanto, Adisasmito W. A spatial-temporal description of the SARS-CoV-2 infections in Indonesia during the first six months of outbreak. PLoS One. 2020 Dec;15(12):e0243703.
Xiao G, Hu H, Wu F, Sha T, Zeng Z, Huang Q, et al. Acute kidney injury in patients hospitalized with COVID-19 in Wuhan, China: a single-center retrospective observational study. Nan Fang Yi Ke Da Xue Xue Bao. 2021 Feb;41(2):157–63.
Satria RMA, Tutupoho RV, Chalidyanto D. Analisis faktor risiko kematian dengan penyakit komorbid COVID-19. J Keperawatan Silampari. 2020;4(1):48–55.
Bennett KE, Mullooly M, O’Loughlin M, Fitzgerald M, O’Donnell J, O’Connor L, et al. Underlying conditions and risk of hospitalisation, ICU admission and mortality among those with COVID-19 in Ireland: A national surveillance study. Lancet Reg Heal Eur. 2021 Jun;5.
Juan J, Gil MM, Rong Z, Zhang Y, Yang H, Poon LC. Effect of coronavirus disease 2019 (COVID-19) on maternal, perinatal and neonatal outcome: systematic review. Ultrasound Obstet Gynecol. 2020 Jul;56(1):15–27.
Pan L, Mu M, Yang P, Sun Y, Wang R, Yan J, et al. Clinical Characteristics of COVID-19 Patients With Digestive Symptoms in Hubei, China: A Descriptive, Cross-Sectional, Multicenter Study. Am J Gastroenterol. 2020 May;115(5):766–73.
Rusdiana T, Akbar R. Perkembangan Terkini Terapi Antikoagulan Pada Pasien Covid-19 Bergejala Berat. J Sains Farm Klin Vol 7, No 3 J Sains Farm Klin 7(3), Desember 2020. 2020;
Tan C. Trombosis Pada Pasien COVID-19. Cermin Dunia Kedokt. 2021;48(12):684–91.
Nugrahani A, Fauzi L, Kesehatan Masyarakat J, Ilmu Keolahragaan F, Negeri Semarang U. RISIKO MORTALITAS PASIEN COVID-19 (STUDI KOHORT RETROSPEKTIF DI RUMAH SAKIT RUJUKAN COVID-19). HIGEIA (Journal Public Heal Res Dev. 2022 Apr;6(2).
Burhan E, Susanto AD, Nasution SA, Ginanjar E, Pitoyo CW, Susilo A, et al. Pedoman tatalaksana Covid-19 [Internet]. 3rd ed. Burhan E, Susanto AD, Isbaniah F, Nasution SA, Ginanjar E, Pitoyo CW, et al., editors. Protokol Tatalaksana Covid-. Jakarta; 2020. 49–55 p. Available from: https://www.papdi.or.id/pdfs/983/Buku Pedoman Tatalaksana COVID-19 5OP Edisi 3 2020.pdf
- Every manuscript submitted to must observe the policy and terms set by the Jurnal Berkala Epidemiologi
- Publication rights to manuscript content published by the Jurnal Berkala Epidemiologi is owned by the journal with the consent and approval of the author(s) concerned. (download copyright agreement)
- Complete texts of electronically published manuscripts can be accessed free of charge if used for educational and research purposes according to copyright regulations.
JBE by Universitas Airlangga is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
