TUBERCULOSIS PREVENTIVE THERAPY AS A STRATEGY TO PREVENT AND CONTROL TUBERCULOSIS INCIDENCE 2010-2024: A BIBLIOMETRIC ANALYSIS

Terapi Pencegahan Tuberkulosis sebagai Strategi Pencegahan dan Pengendalian Kejadian Tuberkulosis 2010-2024: Analisis Bibliometrik

Tuberculosis Bibliometric Isoniazid PubMed

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31 May 2025

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ABSTRACT

Background: Tuberculosis (TBC) is a contagious infectious disease that is the leading cause of death in the world. TPT is one of the ways that needs to be done as a strategy in controlling and eradicating TBC at the community and individual level.

Purpose: To identify research trends related to TBC preventive therapy (TPT) as a strategy to prevent and control TBC incidence. Methods: This study uses a systematic literature review approach and meta-analysis procedures, using Scopus and PubMed databases accessed through the Publish or Perish (PoP) platform, from 2010 -2024, totalling 266 literatures. The literature search was conducted in December 2024.  Data analysis was carried out by filtering abstracts and keywords of literature using the Mendeley application which produced 109 literatures and bibliometric analysis using the VOSViewer 1.6.20 application. Results: IPT (Isoniazid Preventive Therapy) has a close relationship with Preventive therapy, tuberculosis, child, contact and HIV. Other results also show that the number of publications that discuss TPT from 2020 to 2024 has decreased from 23 to 2 publications and the latest research topics related to TPT are only found in 2019. Conclusion: Publications related to TPT from 2020-2024 continue to decline, therefore it is necessary to increase research or research related to TPT in order to provide more complete and extensive information for health agencies in conducting TPT programmes.