TUBERCULOSIS PREVENTIVE THERAPY AS A STRATEGY TO PREVENT AND CONTROL TUBERCULOSIS INCIDENCE 2010-2024: A BIBLIOMETRIC ANALYSIS
Terapi Pencegahan Tuberkulosis sebagai Strategi Pencegahan dan Pengendalian Kejadian Tuberkulosis 2010-2024: Analisis Bibliometrik

Downloads
Background: Tuberculosis Preventive Therapy (TPT) is important in TBC control and elimination strategies at the individual and community levels. However, few studies have systematically mapped developing scientific themes and trends related to TPT, primarily through bibliometric analyses. Therefore, a comprehensive bibliometric study is needed to identify key research foci and gaps in the current TPT knowledge pool. Purpose: This study aimed to identify global research trends in TPT as a preventive strategy to reduce TBC incidence. Methods: This study used a systematic literature review approach and bibliometric analysis using Scopus and PubMed databases through the Publish or Perish (PoP) platform, publications from 2010 to 2024. The initial search yielded 266 articles, which were screened using Mendeley for abstracts and keywords, resulting in 109 relevant publications. Bibliometric analyses were then conducted using VOSviewer version 1.6.20. Results: IPT (Isoniazid Preventive Therapy) has a close relationship with Preventive therapy, tuberculosis, child, contact, and HIV. Other results also show that the number of publications discussing TPT from 2020 to 2024 has decreased from 23 to 2, and the latest research topics related to TPT were only found in 2019. Conclusion: Publications related to TPT from 2020-2024 continue to decline; therefore, it is necessary to revitalize research related to TPT, especially by exploring issues that have not been widely discussed, such as the implementation of TPT in high-risk groups other than children and PLHIV, such as people with chronic diseases, the elderly, and populations with limited access to health services.
Agustin L, Isnawati IA, Hamim N. The relationship between family support and the completion of tuberculosis prevention therapy (TPT) in cases of close contact with pulmonary TB patients at community health centers. J Ilmu Kesehat. 2023;39–47.
Safitri IN, Martini M, Adi MS, Wurjanto MA. Factors related to acceptance of TB preventive therapy in Tegal Regency. J Ris Kesehat Masy. 2023;3(4):212–20.
Trisno Z, Hidayat AN. The relationship between knowledge and perceptions of providing tuberculosis prevention therapy (TPT) among TB program managers at health centers in Sumenep Regency. J Ris Kefarmasian Indones. 2024;6(2):310–28.
World Health Organization. Global report Tuberkulosis 2024. 2024.
Ressa Stevany, Yuldan Faturrahman AS. Analysis of risk factors for tuberculosis incidents in the working area of the Cipinang Besar Utara sub-district health center, East Jakarta administrative city.. J Kesehat komunitas Indones. 2021;17(2):25–32.
Ministry of Health of the Republic of Indonesia. Technical guidelines for handling latent tuberculosis infections. Kemenkes. 2020. 978–979 p.
Selamet Susanto. Increased findings of pulmonary TB cases in 2024 in Tangen District with the presence of molecular rapid tests (TCM) at the Tangen Health Center. Indones Res J Educ Web. 2024;4:550–8.
Ng JY, Liu H, Masood M, Stephen D, Ayala AP, Sabé M, et al. Guidance for the Reporting of Bibliometric Analyses : A Scoping Review. 2024. 1–47 p.
Jasmadi, Lasri, Roslina A. Djalil, Zamzami, Junaidi M, Rizal M. Utilization of the search publish or perish 8 algorithm system as a development of lecturer literature in producing scientific publications at Al Washliyah Darussalam University, Banda Aceh. J Agama dan Sos Hum. 2024;`1:2338–41.
Umniyati H, Ranakusuma O, Sari W, Fitri C, Gigi FK, Psikologi F, et al. Socialization of TB and Tuberculosis prevention therapy (TPT) to stakeholders in four districts of central Jakarta administrative city. 2024;(2):28–36.
Fadhilah N, Kurniawan I, Budianto A, Kesehatan Universitas Muhammadiyah Pringsewu F. Tuberculosis Prevention (TPT) in families of pulmonary TB sufferers. Sci J Nurs Heal. 2024;2(1):62–71.
Suratmini D, Berliana Togatorop L. The relationship between stigma and self-efficacy with adherence to anti-tuberculosis drug (oat) treatment in tuberculosis patients: a literature review. J Keperawatan Widya Gantari Indones. 2023;7(2):115–25.
Gupta A, Singh P, Aaron L, Montepiedra G, Chipato T, Stranix-Chibanda L, et al. Timing of maternal isoniazid preventive therapy on tuberculosis infection among infants exposed to HIV in low-income and middle-income settings: a secondary analysis of the TB APPRISE trial. Lancet Child Adolesc Heal. 2023;7(10):708–17.
Kadyrov M, Thekkur P, Geliukh E, Sargsyan A, Goncharova O, Kulzhabaeva A, et al. Contact tracing and tuberculosis preventive therapy for household child contacts of pulmonary tuberculosis Patients in the Kyrgyz Republic: How Well Are We Doing? Trop Med Infect Dis. 2023;8(7).
Alvi Y, Philip S, Anand T, Chinnakali P, Islam F, Singla N, et al. Situation analysis of early implementation of programmatic management of tuberculosis preventive treatment among household contacts of pulmonary tb patients in Delhi, India. Trop Med Infect Dis. 2024;9(1):1–15.
Herawati C, Abdurakhman RN, Rundamintasih N. The role of family support, health workers and perceived stigma in increasing medication compliance in patients with pulmonary tuberculosis. Kesehat Masy Indones. 2020;15(1):19–23.
Fatikha AN, Martini M, Hestiningsih R, Kusariana N. Spatial analysis of a tuberculosis incidence in Magelang City in 2021. Dis Prev Public Heal J. 2021;16(1):37–46.
Liu C, Yang M, Chen Q, Jia J, Zhao Z, Xu J, et al. Transmissibility and control of tuberculosis: a modeling study based on four outbreaks in China. BMC Infect Dis. 2022;
An Y, Khun KE. Factors associated with incomplete tuberculosis preventive treatment: a retrospective analysis of six-years programmatic data in Cambodia. Sci Rep. 2024;14(1):1–7.
Shanbag N, Haseeb M, Engade M, Siddiqui MS, Badaam KM, Nelanuthala M. Childhood tuberculosis and isoniazid preventive therapy among household contacts of sputum positive pulmonary tuberculosis patients: a descriptive observational study. Cureus. 2022;14(7).
Beatrix Marendeng, Yanri EK. evaluasi program pemberian terapi pencegahan tuberkulosis (tpt) pada pasien hiv. Univeristas Gajah Mada. 2024;
Geremew D. The protective effect of isoniazid preventive therapy on tuberculosis incidence among HIV positive patients receiving ART in Ethiopian settings: A meta-analysis. BMC Infect Dis. 2019;19(1).
Sikesa IGPH, Somia IKA. Isoniazid prophylaxis is a protective factor for tuberculosis incidence in HIV/AIDS patients at the VCT clinic at Sanglah General Hospital, Denpasar. J Penyakit Dalam Udayana. 2021;5(2):51–5.
- Every manuscript submitted to must observe the policy and terms set by the Jurnal Berkala Epidemiologi
- Publication rights to manuscript content published by the Jurnal Berkala Epidemiologi is owned by the journal with the consent and approval of the author(s) concerned. (download copyright agreement)
- Complete texts of electronically published manuscripts can be accessed free of charge if used for educational and research purposes according to copyright regulations.
JBE by Universitas Airlangga is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.