Differences in Blood Glucose Levels of Rats (Rattus norvegicus) Given Sugar Cane Juice and Cyclamate Solution as a Sweetener
Downloads
Background: Artificial sweeteners can cause glucose intolerance, which is a condition where the glucose in the blood is abnormal. Purpose: This research was conducted to determine the difference in blood glucose levels of mice as experimental animals that were given sugarcane juice as a natural sweetener and cyclamate solution as an artificial sweetener. Methods: The research method applied was laboratory experimental followed by checking blood glucose levels using a GCU easy touch glucometer and the data analysis method used was descriptive analysis. Results: the average blood sugar before treatment was P0 (control) 110 mg/dl, P1 (test animals given sugarcane juice solution) 63 mg/dl, P2 (test animals given sodium cyclamate solution) 69.5 mg/dl . Then, the average blood sugar after treatment was, P0 (control) 77.5 mg/dl, P1 (test animals given sugar cane juice) 81.5 mg/dl, P2 (test animals given cyclamate solution) 101.5 mg/dl etc. From this data, it was obtained that the level of glucose in the blood decreased by an average of 32.5 for P0. Then, there was an increase in blood glucose levels with an average of 18.5 for P1. In addition, there was an increase in blood glucose levels with an average of 32 for P2. Blood sugar levels in the treatments given cyclamate and sugar cane juice both experienced an insignificant increase in blood sugar, but within two weeks the average increase in blood sugar was highest in the treatment given cyclamate. Conclusion: There are differences in blood glucose levels of mice as experimental animals given sugarcane juice as a natural sweetener and cyclamate solution as an artificial sweetener.
Agung, B., W. Handang & M. Mirandy, P.S. 2013. Peningkatan kualitas post thawing spermatozoa epididimis sapi dengan suplementasi catechin sebagai antioksidan pada pengencer semen. J Ilmu Ternak 13:34-36.
Ansar, NAzaruddin and Aziz, A.D., 2019. Pengaruh suhu dan lama penyimpanan terhadap perubahan pH dan warna nira aren (Arengga pinnata Merr) setelah penyadapan. Teknik Pertanian LAmpung, pp.97-106.
Cahyadi, W, 2008, Analisa Dan Aspek Kesehatan Bahan Tambahan Pangan, Edisi Kedua, Bumi Aksara, Jakarta
Casu, R.E., Grof, C.P.L., Rae, A.L., Mclntyre, C.L., Dimmock, C.M. & Manners, J.M.(2003). Identification of a novel sugar transporter homologue strongly expressed in maturing stem vascular tissues of sugarcane by expressed sequence tag and micro array analysis. Plant Mol. Biol. 10,1-16.
Chattopadhyay, S., Raychaudhuri, U., & Chakraborty, R. (2014). Nonnutritive sweeteners–a review. J Food Sci Technol, 51(4), 611–621.
Devitria, R., & Sepryani, H. (2018). Identifikasi Natrium Siklamat pada Minuman Sirup yang dijual di Lima SD Kecamatan Sukajadi Pekanbaru. Klinikal Sains: Jurnal Analis Kesehatan, 6(1), 1-7.
Dewi, S.R., Izza, N., Agustiningrum, D.a., Indriani, D.W., Sugiarto,Y., Mahawani, D.M and Yulianingsih, R., 2014. Pengaruh suhu pemasakan Nira dan Kecepatan pengadukan terhadap kualitas gula merah tebu. Jurnal teknologi Pertanian, 15(3), pp.149-158
Dharma Audi Samsuri, Samsuri, Anak Agung Sagung Kendran. 2020. Kadar Glukosa Darah Tikus Putih (Rattus norvegicus) yang Diberikan Ragi Tape. 9(4):531-539. Fakultas Kedokteran Hewan, Universitas Udayana.
Elsevier. 2016. Artificial sweeteners. Meyler's Side Effects of Drugs (Sixteenth Edition). 713-716.
Erwinda, M. D. dan Wahono Hadi Susanto. 2014. Pengaruh pH Nira Tebu (Saccharum offinarum) dan Konsentrasi Penambahan Kapur Terhadap Kualitas Gula Merah. Jurnal Pangan dan Agroindustri Vol.2 No.3 p.54-64. Universitas Brawijaya, Malang.
Fontaine, D. 2019. 5 Common Questions for Diabetic Models. https://www.jax.org/news-and-insigh ts/jax-blog/2019/september/5-common-questions-for-diabetic-models#:~: text=For%20%27healthy%27%2C% 20non%2D,a%204%20%E2%80%93%206%20hour%20fast [7 November 2023].
Harlita. T. D., Rukmana, D. I., dan Nabillah. Z. (2023). Pengaruh Suhu Dan Waktu Penyeduhan Teh Kering Dalam Kemasan Terhadap Angka Kuman, Jurnal Sains Medisina, 1(3), 148–153.
Hedrich HJ. 2006. Taxonomy and stock and strains. J Lab Rat 71-92.
Lawrence, J. F. 2003. CYCLAMATES. Encyclopedia of Food Sciences and Nutrition (Second Edition), Academic Press. 1712-1714.
Lia Melinda, Deny Kurniawan, Vita Pramaningsih. 2022. Identifikasi Pemanis Buatan (Siklamat) pada Penjual Minuman Es Teh Keliling di Sekolah Dasar Kelurahan Melayu Kecamatan Tenggarong. Environmental Occupational Health and Safety Journal. Vol.3 No.1.
Malole, M. B. M. dan C. S. Pramono. 1989. Penggunaan Hewan-hewan Percobaan Laboratorium. Departemen Pendidikan dan Kebudayaan. Direktorat Jendral Pendidikan Tinggi Pusat Antar Universitas Bioteknologi. Institut Pertanian Bogor, Bogor.
Natawijaya,D., Suhartonoand Undang, 2018. The analys of Sap Water YIeld and Palm Sugar Quality in Tasikmalaya District. Jurnal Agroforestri Indonesia 1(1)1, pp.57-64.
Praja, Denny Indra. (2015). Zat Aditif Makanan: Manfaat dan Bahayanya. Garudhawaca.
Pratama, O. W. P., Wuryanto, M. A., & Ginandjar, P. (2018). Gambaran Kadar Gula Darah Sewaktu Pada Penduduk Risiko Tinggi Diabetes Mellitus Tipe 2 Desa Ketawangrejo Kecamatan Grabag Kabupaten Purworejo. Global Health Science, 3(4), 287-293.
Ramadhani, N., Herlina, H., & Utama, A. J. F. (2018). Penetapan Kadar Natrium Siklamat Pada Minuman Ringan Kemasan Dengan Menggunakan Metode Spektrofotometri UV. Jurnal Mandala Pharmacon Indonesia, 4(1), 7–12.
Riswandi, M. D. 2022. Bagaimana Tebu Diolah Menjadi Gula Pasir di Pabrik PT RMI.https://home.rejosomanisindo.c om/104/bagaimana-tebu-diolah-menj adi-gula-pasir-di-pabrik-pt-rmi [7 November 2023]
S, C. S. ., Defanny, & Rakhmadi, F. A. (2020). Karakteristik Resistansi Air Teh Gula Alami dan Buatan. Prosiding Seminar Nasional Fisika Festival, 1, 32–35.
Setiady, F. (2019). Pengaruh Konsumsi Kombinasi Pemanis Buatan Siklamat dan Sakarin terhadap Kadar Glukosa Darah dan Toleransi Glukosa. Jurnal Mahasiswa PSPD FK Universitas Tanjungpura, 5(1).
Smith, J.B., & Mangkoewidjojo,S. (1998). Pemeliharaan, Pembiakan, dan Penggunaan Hewan Percobaan di Daerah Tropis.Tikus Laboratorium (Ratus norvegicus) : 37-57.Penerbit Universitas Indonesia
Sugiyono. 2015. Metode Penelitian Kombinasi (Mix Methods). Bandung. Alfabeta.
Sugiyono. 2016. Metode Penelitian Kuantitatif, Kualitatif, R&D. Bandung: IKAPI.
Sulistiyanto, T. Q., Sinaga, S. M., & Suryanda, A. (2021). Pemahaman dan Perspektif Mahasiswa Mengenai Manfaat Air Tebu (Saccharum officinarum) dalam Prospek Kesehatan. Jurnal Pro-Life, 8(3), 199-204.
Wasudevan, D.M, Sreekumari S dan Kannan Vaidyanthan. 2013. Textbook Of Biochemistry For Medical Student:seven edition. New Delhi: Jaypee Brother Medical Publisher.
Winarno, F.G., 1992, Kimia Pangan dan Gizi, PT. Gramedia Pustaka Utama, Jakarta.
Wolfensohn, S., dan Lloyd, M., 2013, Handbook of Laboratory Animal Management and Welfere, 4th ed., Wiley- Blackwell West Sussex,234.
Copyright (c) 2024 Virginia Ayu Kinanti, Melynda Veronika Kartjito, Inas Zhafira, Anastasia Josephine Saputra, Rahma Alfiana, Aldena Aulia Pramesti Harnowo, Rafael Azkal Vellano, Zulfa Fajrina Handini, Nadia Puteri Amrullah
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Journal of Basic Medical Veterinary (JBMV) by Unair is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
1. The journal allows the author to hold the copyright of the article without restrictions.
2. The journal allows the author(s) to retain publishing rights without restrictions
3. The legal formal aspect of journal publication accessibility refers to Creative Commons Attribution Share-Alike (CC BY-SA).
4. The Creative Commons Attribution Share-Alike (CC BY-SA) license allows re-distribution and re-use of a licensed work on the conditions that the creator is appropriately credited and that any derivative work is made available under "the same, similar or a compatible license”. Other than the conditions mentioned above, the editorial board is not responsible for copyright violation.
Perhimpunan Dokter Hewan Indonesia
