Potential Combination of Bittern Water with Vitamin B Complex for Mineral Deficiency Therapy in Cattle: A Literature Study
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Bittern water is a byproduct of the crystallization process from the manufacture of salt which have high concentrations of magnesium, calcium, potassium and other trace minerals Bittern water is known to treat osteoporosis, postprandial hyperlipidemia, oral infections and increase salivary secretion. The mineral content in bittern water is not only beneficial for humans but also for animal health. Cows are one of the animals that are prone to various health problems such as mineral balance and metabolism disorders in the body, especially during pregnancy and after giving birth. In addition to minerals, vitamin B complex is often used to improve the health quality of cows. However, until now, the use of bittern water and the combination with vitamin B complex for animal treatment is still very rare. The formulation of multivitamin-mineral preparations is quite complex to do so that there are several things that need to be considered in order to obtain a good and quality formula. This review article was created to gather information regarding the benefits of the mineral content contained in bittern water and vitamin B complex as a treatment to treat various health problems for cattle, as well as what important factors should be considered in multivitamin-mineral preparations. Based on literature search, it was found that the combination of bittern water and vitamin B complex has the potential to overcome health problems in cows, where the main minerals in bittern water are proven to improve magnesium status in the blood, increase calcium intake and reduce the incidence of milk fever, increase milk production and components, and improve immune status. While vitamin B complex is widely used as a supplement to increase metabolism, energy status in cows balances rumen pH, maintains microbiota balance in riumen and helps increase milk production. The combination of bittern water and vitamin B complex can synergistically improve mineral status, energy, and immune response, as well as improve disease symptoms. There are also important factors that must be considered in multivitamin-mineral dosage formulations for animals, namely bioavailability, stability, and dosage form.
Ansel, H. C. (1989). Pengatar Bentuk sediaan Farmasi. Jakarta: UI Press.
Astiti, L. G., & Hijirah. (2017). Efektivitas Vitamin B-Kompleks terhadap Gambaran Hematologi Sapi Bali Bunting dan Post-Partus. Prosiding Seminar Nasional Teknologi Peternakan dan Veteriner 2017.
Bach, A., Isabel, G., Guillermo, E., Julie, D., & Hajer, K. A. (2018). Modulation of Rumen pH By Sodium Bicarbonate And A Blend of Different Sources of Magnesium Oxide In Lactating Dairy Cows Submitted To A Concentrate Challenge. Journal of Dairy Science, 101(11), 1-12.
Bai, B. S., & Vaithyanathan, C. (2015). Studies on The Chemical Parameters of Brine At Various Stages of Different Salt-Pans Of Kanyakumari District, Tamil Nadu, India. Journal of Chemical and Pharmaceutical Research, 7(7), 430-439.
Beauchemin, K. A. (2018). Current Perspectives On Eating and Rumination Activity in Dairy Cows. Journal of Dairy Science, 101(6), 4762-4784.
Benkhedda, K., L'abbe, M., & Cockell, K. A. (2010). Effect of Calcium On Iron Absorption In Women With Marginal Iron Status. The British Journal of Nutrition, 103(5), 742–748.
Chen, B., Wang, C., Wang, Y., & Liu, J. X. (2011). Effect of Biotin On Milk Performance of Dairy Cattle: A Meta-Analysis. Journal of Dairy Science, 94(7), 3537–3546.
Depkes, R. (1995). Farmakope Indonesia (4 ed.). Jakarta: Departemen Kesehatan Republik Indonesia.
DeVries, T. J., Beauchemin, K. A., Dohme, F., & Schwartzkopf, K. S. (2009). Repeated Ruminal Acidosis Challenges In Lactating Dairy Cows At High And Low Risk For Developing Acidosis: Feeding, Ruminating, And Lying Behavior. Journal Dairy Science, 92(10), 5067-5078.
Duplessis, M., Girard, C. L., Santschi, D. E., Laforest, J. P., Durocher, J., & Pellerin, D. (2014). Effects Of Folic Acid And Vitamin B12 Supplementation on Culling Rate, Diseases, And Reproduction In Commercial Dairy Herds. Journal of Dairy Science, 97(4), 2346-2354.
Ginane, C., René, B., & Angélique, F. (2011). Perception and Hedonic Value of Basic Tastes in Domestic Ruminants. Physiology & Behavior, 104, 666–674.
Girard, C. L., & Matte, J. J. (2006). Impact of B-Vitamin Supply on Major Metabolic Pathways of Lactating Dairy Cows. Canadian Journal of Animal Science, 86(2), 213-220.
Goff, J. (2008). The Monitoring, Prevention and Treatment Of Milk Fever And Subclinical Hypocalcemia In Dairy Cows. The Veterinary Journal, 176(1), 50-57.
Goff, J. P. (2006). Macromineral Physiology and Application To The Feeding of The Dairy Cow For Prevention of Milk Fever and Other Periparturient Mineral Disorders. Animal Feed Science Tech, 126(3-4), 237-257.
Graulet, B., Matte, J. J., Desrochers, A., Doepel, L., Pallin, M. F., & Girard, C. L. (2007). Effects of Dietary Supplements of Folic Acid And Vitamin B12 On Metabolismof Dairy Cows In Early Lactation. Journal of Dairy Science, 90(7), 3442-3455.
Grummer, R. (2008). Nutritional And Management Strategies For The Prevention of Fatty Liver In Dairy Cattle. Veterinary Journal, 176, 10-20.
Hapsari, N. (2008). Proses Pemisahan Ion Natrium (Na) dan Magnesium (Mg) Dalam Bittern (Buangan) Industri Garam Dengan Membran Elektrolisis. Jurnal Teknik Kimia, 3(1), 192-198.
Harper, M. T., Oh, J., Giallongo, F., Lopes, J. C., Weeks, H. L., Faugeron, J., & Hristov, A. N. (2016). Short communication: Preference for flavored. Journal Science of Dairy Cow, 99, 6585–6589.
Hellmann, H., & Mooney, S. (2010). Vitamin B6: A Molecule for Human Health. Molecules, 15(1), 442-459.
Herdt, T., & Hoff, B. (2011). The Use of Blood Analysis to Evaluate Trace Mineral Status in Ruminant Livestock. Veterinary Clinics of North America: Food Animal Practice, 27(2), 255 - 283.
Hussein, A. A., Zohdy, K., & Abdelkreem, M. (2017). Seawater Bittern A Precursor For Magnesium Chloride Separation. International Journal of Waste Resources, 7(1), 1-6.
Jackson, T. D., Carmichael, R. N., Deters, E. L., Messersmith, E. M., VanValin, K. R., Loy, D. D., & Hansen, S. L. (2020). Comparison of Multiple Single-Use, Pulse-Dose Trace Mineral Products Provided As Injectable, Oral Drench, Oral Paste, Or Bolus On Circulating And Liver Trace Mineral Concentrations Of Beef Steers. Applied Animal Science, 36(1), 26-35.
Javier, M., & Martens, H. (2014). Calcium and Magnesium Physiology and Nutrition in Relation to the Prevention of Milk Fever and Tetany (Dietary Management of Macrominerals in Preventing Disease). Veterinary Clinics of North America: Food Animal Practice, 30(3), 643-670.
Jones, G., & Tracy, B. (2013). Evaluating Seasonal Variation In Mineral Concentration Of Cool-Season Pasture Herbage. Grass and Forage Science, 69, 1-8.
Judjono, S., Agung, R., & Nyoman, P. A. (2010). Pembuatan Kristal Epsomite Dari Air Tua. Retrieved Juni 25, 2020, from http://eprints.undip.ac.id/27993/1/C-09.pdf
Kishimoto, Y., Tani, M., Uto-kondo, H., Saita, E., & Kondo, K. (2010). Effects of Magnesium On Postprandial Serum Lipid Responses In Healthy Human Subjects. British Journal of Nutrition, 103, 469-472.
KKP. (2013). Profil Keluatan dan Perikanan Propinsi Jawa Timur Untuk Mendukung Industrialisasi Kelautan Perikanan. Kementrian Kelautan dan Perikanan: Kantor Pusat Data Statistika dan Informasi Sekertariat Umum.
Kronqvist, C., Emanuelson, U., Traven, M., Sporndly, R., & Holtenius, K. (2012). Relationship Between Incidence of Milk Fever And Feeding of Minerals During The Last 3 Weeks of Gestation. Animal, 6(8), 1316–1321.
Lean, I. J., & Rabiee, A. R. (2011). Effect of Feeding Biotin On Milk Production And Hoof Health In Lactating Dairy Cows: A Quantitative Assessment. Journal of Dairy Science, 94(3), 1465-1476.
Li, H. Q., Liu, Q., Wang, C., Yang, Z. M., Guo, G., Huo, W. J., Liu, P. X. (2016). Effects of Dietary Supplements of Rumen-Protected Folic Acid On Lactation Performance, Energy Balance, Blood Parameters And Reproductive Performance In Dairy Cows. Animal Feed Science and Technology, 213, 55-63.
Liu, H. Y., Liu, M. C., Wang, M. F., & Chen, W. H. (2013). Potential Osteoporosis Recovery by Deep Sea Water through Bone Regeneration in SAMP8 Mice. Evidence-Based Complementary and Alternative Medicine, 2013, 1–11.
Lychnos, G., Fletcher, J. P., & Davies, P. A. (2010). Properties of Seawater Bitterns With Regard To Liquid Desiccant Cooling. Desalination, 250(1), 172-178.
Majee, D. N., Schwab, E. C., Bertics, S. J., Seymour, W. M., & Shaver, R. D. (2003). Lactation Performance By Dairy Cows Fed Supplemental Biotin And B-Vitamin Blend. Journal of Dairy Science, 86(6), 2106-2112.
Monajjemzadeh, F., Fatemeh, E., Parvin, Z. M., & Hadi, V. (2014). Effects of Formulation Variables and Storage Conditions on Light Protected Vitamin B12 Mixed Parenteral Formulations. Advance Pharm Bull, 4(4), 329-338.
Morales, M. S., & Dehority, B. A. (2014). Magnesium Requirement of Some of The Principal Rumen Cellulolytic Bacteria. Animal, 8(9), 1427-1432.
Nakajima, Y., Mikami, O., Yoshioca, M., & Motoi, Y. (1997). Elevated Levels of Tumor Necrosis Factor-Alpha (Tnf-Alpha) And Interleukin-6 (IL-6) Activities In The Sera And Milk of Cows With Naturally Occurring Coliform Mastitis. Research in Veterinary Science, 62(2), 297-298.
Nayak, N. (2018). Major and Trace Element Determination in Brine and Bittern. Indian Journal of Research, 7(7), 36-38.
NRC. (2001). Subcommittee on Dairy Cattle Nutrition. Committee on Animal Nutrition: National Research Council.
Odette, O. (2005). Grass Tetany In A Herd of Beef Cows. Canadian Veterinary Journal, 46(8), 732-734.
Ohtsu, M., M., T., H., S., S., S., & Asano, M. (2017). Effects of Bittern Water on Cariogenic Bacteria and Saliva Secretion. Journal of Oral Science, 59(3), 453-456.
Ollivett, T. L., & McGuirk, S. (2013). Salt Poisoning As A Cause of Morbidity and Mortality in Neonatal Dairy Calves. Journal Veterinary Internal Medicine, 27(3), 592-595.
Pan, H. X., L., Y., Xue, F. G., Xin, H. R., Jiang, J. S., Xiong, B. H., & Beckers, Y. (2016). Relationship Between Thiamine And Subacute Ruminal Acidosis Induced By A High-Grain Diet In Dairy Cows. Journal of Dairy Science, 99(11), 8790-8801.
Perry, R. H., & Don, W. G. (2008). Perry's Chemical Engineers' Handbook. (8th ed.). New York: McGraw-Hill.
Petri, R. M., Schwaiger, T., G., P. B., Beauchemin, K. A., Foster, R. J., McKinnon, J. J., & McAllister, T. A. (2013). Characterization of The Core Rumen Microbiome in Cattle During Transition From Forage To Concentrate As Well As During And After An Acidotic Challenge. PLoS One, 8, 83424.
Plumb, D. C. (2008). Plumb's Veterinary Drug Handbook (6th ed.). New York: Blackwell Publishing.
Quist-Jensen, C., Macedonio, F., & Drioli, E. (2016). Integrated Membrane Desalination Systems with Membrane Crystallization Units for Resource Recovery: A New Approach For Mining From The Sea. Crystals, 6(4), 36.
Retno, W., Sugunavathy , P., Herwin, P., Mirnawati, S. B., & Afton, A. (2017). Kadar Kalsium pada Sapi Perah Penderita Mastitis Subklinis di Pasir Jambu, Ciwidey. Acta Veterinaria Indonesiana, 5(1), 16-21.
Russell, L. F. (2012). Water Soluble Vitamins in Food Analysis. Florida: CRC Press.
Saborío-Montero, A., Vargas-Leitón, B., Romero-Zúñiga, J. J., & Sanchez, J. M. (2017). Risk Factors Associated With Milk Fever Occurrence In Grazing Dairy Cattle. Journal of Dairy Science, 100(12), 9715-9722.
Sacadura, F., Robinson, P. H., Evans, E., & Lordelo, M. (2008). Effects of A Ruminally Protected B-Vitamin Supplement On Milk Yield And Composition of Lactating Dairy Cows. Animal Feed Science And Technology, 144(1-2), 111–124.
Santoso, J., Oliviera, J. A., Mendiola, J., & Herrero, M. (2011). Sequential Determination of Fat- and Water-Soluble Vitamins in Green Leafy Vegetables During Storage. Journal of Chromatography, 1261, 179–188.
Santschi, D. E., Berthiaume, R., Matte, J. J., Mustafa, A. F., & Girard, C. L. (2005). Fate of Supplementary B-Vitamins in The Gastrointestinal Tract of Dairy Cows. Journal of Dairy Science, 88(6), 2043-2054.
Schauff, D. (2014). The Importance of Macro-Minerals, Magnesium. The Agri-King Advantage, 5(3), 1-4.
Schonewille, T. (2013). A Review : Magnesium In Dairy Cow Nutrition. Plant Soil, 368, 167-178.
Setiawan, R., Kundrat, H., & Dwi, C. B. (2014). Studi AsosiasiAntara Masa Kosong (Days Open) Terhadap Produksi Susu dan Kerugian Ekonomi Pada Peternakan Sapi Perah Di Kabupaten Garut. Jurnal Ilmu Ternak, 1(4), 17 - 21.
Shargel, L., Yu, A., & Wu, S. (2005). Biofarmasetika dan Farmakokinetika Terapan. Surabaya: Airlangga Press.
Squires, E. (2003). Applied Animal Endocrinology. Cambridge (UK): CAB Pub.
Srinivasan, V. S. (2001). Bioavailability of Nutrients: A Practical Approach To In Vitro Demonstration of The Availability Of Nutrients In Multivitamin-Mineral Combination Products. The Journal Of Nutrition, 131(4), 1349-1350.
Sudibyo, A., & Irma, S. (2011). Studi Pemanfaatan Air Bittern Sebagai Suplemen dan Pengawetan Produk Pangan. Jurnal Hasil Penelitian Industri, 24(2), 67-82.
Susanto, H., Rokhati N., & G.W., S. (2015). Development of Traditional Salt Production Proccess For Improving Product Quantity and Quality in Jepara District, Central Java, Indonesia. Procedia Environmental Sciences, 23, 175–178.
Suwasono, B., Aris, W. W., & Ali, M. (2013). Keragaman Kualitas Air Laut, Garam Rakyat, dan Garam Evaporasi Bertingkat Di Wilayah Pesisir Jawa Timur. Jurnal Segera, 9(2), 145-155.
Tebbe, A. W., Wyatt, D. J., & W., W. P. (2018). Effects of Magnesium Source And Monensin on Nutrient Digestibility And Mineral Balance in Lactating Dairy Cows. Journal of Dairy Science, 10(2), 1152-1163.
Tewari, A., Joshi, H. V., Raghunathan, C., Trivedi, R. H., & Ghosh, P. K. (2003). The Effect of Sea Brine and Bittern On Survival and Growth Mangrove avicennia marina. Indian Journal of Marine Sciences, 32(1), 52–55.
Ting, C. H., Lien, C. C., & Wan, Y. N. (2016). Online Detection of Dairy Cow Subclinical Mastitis Using Electrical Conductivity Indices of Milk. Engineering In Agriculture, Environment and Food, 9(3), 201-207.
Van De Braak, A. E., Van'tklooster, A. E., & A., M. (1987). Influence of A Deficient Supply of Magnesium During The Dry Period On The Rate of Calcium Mobilisation By Dairy Cows At Parturition. Research in Veterinary Science, 42(1), 101-108.
Volp, A., Bressan, J., Hermsdorff, H., Zulet, M., & Martínez, J. (2010). Selenium Antioxidant Effects and Its Link With Inflammation and Metabolic Syndrome. Review Nutrition, 23(4), 581-590.
Wang, H., Xiaohua, P., Chao, W., Mengzhi, W., & Lihuai, Y. (2015). Effects of Different Dietary Concentrate To Forage Ratio And Thiamine Supplementation on The Rumen Fermentation And Ruminal Bacterial Community In Dairy Cows. Animal Production Science, 55(2), 189-193.
Warken, A. C., Lopes, L. S., Bottari, N. B., Glombowsky, P., Galli, G. M., Morsch, V. M., & Silva, A. S. (2018). Mineral Supplementation Stimulates The Immune System And Antioxidant Responses of Dairy Cows and Reduces Somatic Cell Counts In Milk. Anais Da Academia Brasileira de Ciíªncias, 90(2), 1649-1658.
Zelal, A. (2017). A Review : Hypomagnesemia Tetany in Cattle. Advances in Dairy Research, 5(2), 1-9.
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