Efficacy of Topical Applications on Reducing Uremic Pruritus: A Systematic Review
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Introduction: Uremic pruritus is an unpleasant sensation that has been recognized as a frequent complication in patients with chronic kidney disease. This study was undertaken to determine the effect of topical applications for reducing pruritus.
Methods: A systematic review was conducted by searching Science Direct, Scopus and Google Scholar to create an integrative 12 articles review focusing on a 10 year period from 2009 to 2018. The language used was English and the studies focused on pruritus, itching, hydration, chronic kidney disease and where the patient did not undergo a kidney transplant. The articles in this systematic review were experimental studies (pre-experimental, true experimental and quasi-experimental).
Results: Most of the findings of the studies showed that a topical application for reducing uremic pruritus (clove oil, almond oil, cromolyn sodium 4%, baby oil, sweet almond oil, vinegar and avenasativa, glycerol and paraffin, sericin cream and chia seed oil) can be used as an adjuvant moisturizing agents for pruritis.
Conclusion: Topical applications have a positive effect on itching and decreased pruritus. Topical applications are simple, safe, inexpensive and easily applied, so it can be used on many people.Afrasiabifar, A., Mehri, Z. and Hosseini, N. (2017) ‘Efficacy of topical application of sweet almond oil on reducing uremic pruritus in hemodialysis patients: A randomized clinical trial study', Iranian Red Crescent Medical Journal. doi: 10.5812/ircmj.34695.
Aramwit, P. et al. (2012) ‘Sericin cream reduces pruritus in hemodialysis patients: a randomized, double-blind, placebo-controlled experimental study.', BMC nephrology. doi: 10.1186/1471-2369-13-119.
Balaskas, E. et al. (2011) ‘Randomized, double-blind study with glycerol and paraffin in uremic xerosis', Clinical Journal of the American Society of Nephrology. doi: 10.2215/CJN.05490610.
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EFEKTIVITAS KRIM ALMOND OIL 4% TERHADAP TINGKAT KELEMBAPAN KULIT' (2016) JURNAL KEDOKTERAN DIPONEGORO.
Ibrahim, I. M. et al. (2017) ‘Effectiveness of topical clove oil on symptomatic treatment of chronic pruritus', Journal of Cosmetic Dermatology. doi: 10.1111/jocd.12342.
Jeong, S. K. et al. (2010) ‘Effectiveness of topical chia seed oil on pruritus of end-stage renal disease (ESRD) patients and healthy volunteers', Annals of Dermatology. doi: 10.5021/ad.2010.22.2.143.
Karadag, E. et al. (2014) ‘Effect of baby oil on pruritus, sleep quality, and quality of life in hemodialysis patients: Pretest-post-test model with control groups', Japan Journal of Nursing Science. doi: 10.1111/jjns.12019.
Lin, T. C. et al. (2012) ‘Baby oil therapy for uremic pruritus in haemodialysis patients', Journal of Clinical Nursing. doi: 10.1111/j.1365-2702.2011.03906.x.
Maryam, K. et al. (2013) ‘Efficacy of topical cromolyn sodium 4 % on pruritus of uremic nephrogenic patients ; a randomized double blind study on 60 patients', (March). doi: 10.5414/CP201629.
Mehri, Z., Afrasiabifar, A. and Hosseini, N. (2018) ‘Improved Itchy Quality of Life Following Topical Application of Sweet Almond Oil in Patients with Uremic Pruritus: A Randomized, Controlled Trial', Jundishapur Journal of Chronic Disease Care. doi: 10.5812/jjcdc.68164.
Mokhtarabadi, S. et al. (2017) ‘The Effect of Administration of Baby Oil on the Severity of Pruritus in Hemodialysis Patients', Medical-Surgical Nursing Journal. doi: 10.15171/jrip.2017.22.
Nakhaee, S. et al. (2015) ‘Comparison of Avena Sativa, vinegar, and hydroxyzine for uremic pruritus of hemodialysis patients a crossover randomized clinical trial', Iranian Journal of Kidney Diseases.
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