Hubungan IL-10 dengan Serum Kreatinin dan Terjadinya Komplikasi pada Preeklampsia Perawatan Konservatif
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Tujuan: mengetahui hubungan penurunan IL-10 dengan terjadinya peningkatan serum kreatinin (SK) dan terjadinya komplikasi preeklampsia.
Bahan dan Metode: penelitian ini merupakan analitik observasional yang dilakukan pada 30 wanita preeklampsia berat tipe dini yang dilakukan perawatan konservatif. Dilakukan pemeriksaan IL-10 pada serum darah dengan metode ELISA sebelum perawatan konservatif dan kemudian dinilai luaran maternal (SK dan komplikasi preeklampsia)
Hasil: didapatkan rerata kadar IL-10 pada preeklampsia tipe dini 0,71 ± 0,66 pg/mL, rerata luaran SK 0,83 ± 0,29, terjadinya komplikasi 9 kasus (edema paru, impending eklampsia, sindroma HELLP). Tidak didapatkan hubungan antara IL-10 dengan peningkatan serum kreatinin (p = 0,483) dan komplikasi preeklampsia (p = 0,828).
Simpulan: IL-10 bukan merupakan faktor prediktif untuk luaran maternal pada preeklampsia perawatan konservatif.
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