The correlation of nutritional status with hematology toxicity of adjuvant chemotherapy in ovarian cancer
Downloads
HIGHLIGHTS
1. This retrospective cohort study found an increase in the diagnosis of malnutrition between the IMT method and NRI.
2. A significant correlation was found between preoperative malnutrition and the incidence of anaemia after adjuvant chemotherapy for ovarian cancer patients.
3. There were no significant correlations in this study in the incidence of leukopenia and thrombocytopenia.
ABSTRACT
Objectives: To observe correlation of nutritional status using Nutritional Risk Index with the side effects of adjunctive haematological chemotherapy.
Materials and Methods: This study was a retrospective cohort study observing whether or not hematologic side effects occurred during chemotherapy based on medical records of postoperative ovarian cancer patients receiving adjuvant chemotherapy.
Results: Sixty-eight subjects with age range of 31-50 years (44.1%) multipara (68.8%), and advanced stage (52.1%) were observed. An increase was found in the diagnosis of malnutrition between the IMT method and NRI, which was 18.7% compared to 43.7%. A significant correlation was found between preoperative malnutrition and the incidence of anaemia after adjuvant chemotherapy for ovarian cancer patients (p=0.002). Whereas, in the event of leukopenia and thrombocytopenia, there were no significant correlations with p=0.675 and p=0.415, respectively.
Conclusion: There was an increase in malnutrition rate with the use of NRI compared with BMI and there was a significant correlation between malnutrition and side effects of anaemia in patients with ovarian cancer who underwent surgery and continued with adjuvant chemotherapy.
Survei Demografi Kesehatan Indonesia [Indonesian Health Demographic Survey]. Angka Kematian Ibu dan Bayi [Maternal and Infant Mortality Rate]. 2016.
Xiaolei X, Jingshan L, Swartz CH, DePriest P. Improving response-time performance in acute care delivery: A systems approach. Transactions on Automation Science and Engineering. 2014;11(4). doi: 10.1109/TASE.2013.2258913.
National Collaborating Centre for Women’s and Children’s Health: Decision to delivery interval. 2011.
Pandya T, Mangalampally K. Critical care in obstetrics. Indian J Anaesth. 2018;62(9):724–33. doi: 10.4103%2Fija.IJA_577_18
Departement of Health Royal Australian College of GP. Guidelines for shared maternity care affiliates. State of Victoria: Department of Health Royal Australiasn College of GP. 2010.
Miheso J, Burns S. Care of women undergoing emergency caesarean section; Emergency Cesarean Section Classification. 2015.
Tashfeen K, Patel M, Hamdi IM, et al. Decision-to-delivery time intervals in emergency caesarean section cases. Sultan Qaboos Univ Med J. 2017;17(1):e38–e42. doi: 10.18295/squmj.2016. 17.01.008.
Gately R, San A. Kurtkoti J, Parnham A. Life‐ threatening pregnancy‐associated atypical haemo-lytic uraemic syndrome and its response to eculizumab. Nephrology. 2017. doi: 10.1111/nep. 12938
Morton CH, Van Otterloo RL, Marla J, et al. Translating maternal mortality review into quality improvement opportunities in response to pregnancy-related deaths in California. 2019;48 (3): 252-62. doi: 10.1016/j.jogn.2019.03. 003.
Punches BE, Johnson KD, Acquavita SP, et al. Patient perspectives of pregnancy loss in the emergency department. International Emergency Nursing. 2019;43:61-6. doi: 10.1016/j.ienj.2018. 10.002.
Williams AC, Craig KD. Updating the definition of pain. Pain. 2016;157(11):2420–3. doi: 10.1097/j.pain.0000000000000613.
Duncan LG, Cohn MA, Chao MT et al. Benefits of preparing for childbirth with mindfulness training: a randomized controlled trial with active comparison. BMC Pregnancy Childbirth. 2017;17: 140. doi: 10.1186/s12884-017-1319-3.
Coates D, Makris A, Catling C, et al. A systematic scoping review of clinical indications for induction of labour. PLoS ONE. 2020;15(1):e0228196. doi: 10.1097/ceh.0000000000000289.
Sitras V, Šaltytė Benth J, Eberhard-Gran M. Obstetric and psychological characteristics of women choosing epidural analgesia during labour: A cohort study. PLoS ONE. 2017;12(10): e0186564. doi: 10.1371/journal.pone.0186564.
Hatamleh R, Abujilban S, Shaker A, et al. The effects of a childbirth preparation course on birth outcomes among nulliparous Jordanian women. Midwifery. 2019;72:23-9. doi: 10.1016/j.midw. 2019.02.002.
1. Copyright of the article is transferred to the journal, by the knowledge of the author, whilst the moral right of the publication belongs to the author.
2. The legal formal aspect of journal publication accessibility refers to Creative Commons Attribution-Non Commercial-Share alike (CC BY-NC-SA), (https://creativecommons.org/licenses/by-nc-sa/4.0/)
3. The articles published in the journal are open access and can be used for non-commercial purposes. Other than the aims mentioned above, the editorial board is not responsible for copyright violation
The manuscript authentic and copyright statement submission can be downloaded ON THIS FORM.
