Severe preeclampsia leads to higher prevalence of mortality and morbidity affecting maternal outcomes in single tertiary hospital
Downloads
Objective: The purpose of this study was to determine the maternal outcomes of severe preeclampsia at RSUD Dr. Soetomo Surabaya in January 2013-December 2014.
Materials and Methods: This research was a descriptive study with cross-sectional design to observe maternal characteristics and maternal outcomesof severe preeclampsia. Data were retrieved from medical records of severe preeclampsia patients admitted to Obstetric Ward of Dr Soetomo Hospital, from January 2013 to December 2014. This study used total sampling for collecting its data. These data were proccessed descriptively and presented in graphic, tables, and short description.
Results: From January 2013 to December 2014 there were 386 (44.2%) cases of severe preeclampsia that were included in this study from a total of 874 cases available. The maternal outcomes of severe preeclampsia consisted of 42 cases (10.9%) of HELLP syndrome, 36 cases (9.3%) of pulmonary edema, 225 cases (58.3%) of sectio caesarea, 7 cases(1.8%) of antepartum bleeding with 5 cases (1.3%) of placenta previa and 2 cases (0.5%) of solutio placenta, 2 cases (0.5%) of postpartum bleeding, 8 cases (2.1%) of eclampsia, 31 cases (8%) of impending eclampsia, 5 cases (1.3%) of acute kidney injury, and 2 cases (0.5%) of maternal death.
Conclusion: In conclusion, this study shows that severe pre-eclampsia patients have high prevalence of mortality and morbidities that affects maternal outcomes. It also reccommends that all patients with severe preeclampsia need to receive intensive maternal and fetal care. It is necessary to do careful complication examination, prevention of seizures using magnesium sulfate, and continous fetal and maternal monitoring.Sibai BM. Evaluation and management of severe preeclampsia before 34 weeks gestation. American Journal of Obstetrics and Gynecology. 2011;205 (3):191–8.
Levine J, Karumanchi A. Preeclampsia, a disease of the maternal endothelium: the role of anti-angiogenic factors and implications for later cardiovascular disease. [Internet] [Cited 2015 Aug 10]. Available from: http://www.ncbi.nlm.nih.gov/ pmc/articles/PMC3148781/.
Ministry of Health of Republic Indonesia. Pusat Data dan Informasi Kementerian Kesehatan RI. Jakarta Selatan. 2014.
Dinkes.surabaya.go.id [Internet]. Department of Health of Republic Indonesia. Preeklamsia dan eklamsia penyebab kematian terbesar ibu melahir-kan. Resources [cited 2015 Aug 9]. Available from http://dinkes.surabaya.go.id/portal/index/php/berita/preeklamsia-dan-eklamsia-penyebab-kematian-terbesar-ibu-melahirkan/.
The American College of Obstetricians and Gynecologists Hypertension in Pregnancy-Practice Guideline. 2013.
Ghulmiyyah L, Sibai B. Maternal mortality from preeclampsia/eclampsia. Seminars in Perinatology. 2012;36(1):56–9.
Akbar A, Wicaksono B, Dachlan EG. Maternal mortality and its mainly possible cause pre-eclampsia/eclampsia in developing country (Surabaya, Indonesia as the model). Pregnancy Hypertension, 2012;2(3):184.
Prianita AW. Pengaruh faktor usia ibu terhadap keluaran maternal dan perinatal pada persalinan primigravida di RS Dr. Kariadi Semarang periode tahun 2010. 2011. Unpublished paper.
Duckitt K, Harrington D. Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies. BMJ Clinical Research Ed. 2005;330(7491):565.
Brosens I, Curcic A, Vejnovic T, et al. The perinatal origins of major reproductive disorders in the adolescent: Research avenues. Placenta. 2015; 36(4):341–4.
Raras AA. Pengaruh preeklamsia berat pada kehamilan terhadap keluaran maternal dan perinatal di RSUP Dr Kariadi Semarang Tahun 2010. 2011. p. 1–19.
Sibai BM, Barton JR. Expectant management of severe preeclampsia remote from term: patient selection, treatment, and delivery indications. Am J Obstet Gynecol. 2007;196(6):514.e1-9.
Weiner E, Schreiber L, Grinstein E, et al. The placental component and obstetric outcome in severe preeclampsia with and without HELLP syndrome. Placenta. 47:99–104.
Hermanto, Adityawarman, Sulistyono, et al. The characteristic of Indonesia's pre-eclampsia: From obstetric intensive care with ventilator until epidemiologic and its molecular biology profile of pulmonary edema in severe pre-eclampsia. Pregnancy Hypertension. 2014;4(3):245.
Zhang J, Troendle J, Reddy, et al. Contemporary cesarean delivery practice in the United States. American Journal of Obstetrics and Gynecology. 2003;(4):326.e1-326.e10.
Joost F, von Schmidt auf Altenstadt, Chantal PWM, et al. Pre-eclampsia increases the risk for post-partum haemorrhage: A nationwide cohort study among more than 340,000 deliveries. American Journal of Obstetrics and Gynecology. 2012;206(1), S68.
Thornton C, Dahlen H, Korda A, et al. The incidence of preeclampsia and eclampsia and associated maternal mortality in Australia from population-linked datasets: 2000-2008. American Journal of Obstetrics and Gynecology. 2013;208 (6):476.e1-476.e5.
Curiel-Balsera E, Prieto-Palomino MÁ, Muñoz-Bono, et al. Analysis of maternal morbidity and mortality among patients admitted to Obstetric Intensive Care with severe preeclampsia, eclampsia or HELLP syndrome. Medicina Intensiva (English Edition). 2011;35(8):478–83.
1. Copyright of the article is transferred to the journal, by the knowledge of the author, whilst the moral right of the publication belongs to the author.
2. The legal formal aspect of journal publication accessibility refers to Creative Commons Attribution-Non Commercial-Share alike (CC BY-NC-SA), (https://creativecommons.org/licenses/by-nc-sa/4.0/)
3. The articles published in the journal are open access and can be used for non-commercial purposes. Other than the aims mentioned above, the editorial board is not responsible for copyright violation
The manuscript authentic and copyright statement submission can be downloaded ON THIS FORM.