Cracking The Crimson Conundrum: A Case Report on Granulomatous Rosacea
Background: Rosacea, a prevalent inflammatory skin condition, commonly affects the central facial area. Granulomatous rosacea, a rare variant of rosacea, presents diagnostic intricacies due to its clinical and histopathological resemblance to other granulomatous dermatoses. Purpose: We are presenting this case due to the scarcity of granulomatous rosacea cases, often misdiagnosed, leading to unwarranted treatment options. We describe a case of granulomatous rosacea in a 24-year-old female, elucidating clinical features and diagnostic challenges the patient presented with red, elevated lesions over the central facial region for three months. Clinical examination revealed well-defined erythematous papules. Dermoscopy and histopathological examination confirmed the diagnosis. Discussion: Granulomatous rosacea poses a diagnostic problem, necessitating early recognition and tailored management to prevent facial disfigurement and psychological distress. Differential diagnoses often require careful consideration and may involve a combination of clinical, dermoscopic, and histopathological assessments. Conclusion: This case underscores the importance of considering granulomatous rosacea in the differential diagnosis of other facial dermatoses.
Powell FC, Ni Raghallaigh S. Rosacea and related disorders. In: Bolognia JL, Schaffer JV, Cerroni L, editors. Dermatology. 4th ed. Philadelphia: Elsevier; 2018. p. 604-14.
Farshchian M, Daveluy S. Rosacea. In: StatPearls [Internet]. Treasure Island: StatPearls Publishing; 2024.
Sarkar R, Podder I, Jagadeesan S. Rosacea in skin of color: A comprehensive review. Indian J Dermatol Venereol Leprol 2020;86(5):611-21.
Ren M, Yang X, Teng Y, Lu W, Ding Y, Tao X. Successful treatment of granulomatous rosacea by JAK inhibitor abrocitinib: A case report. Clin Cosmet Investig Dermatol 2023;16:3369-74.
Van Zuuren EJ, Arents BW, van der Linden MM, Vermeulen S, Fedorowicz Z, Tan J. Rosacea: New concepts in classification and treatment. Am J Clin Dermatol 2021;22(4):457-65.
Wu MY, Wu JH, Yang TY, Li YG, Hsu KY, Chen KH. Unilateral granulomatous rosacea: The immunocompromised district is a possible cause. Dermatol Sin 2017;35(4):219-20.
M, Ruzicka T, Steinhoff M, Schaller M, Gieler U, Schöfer H, et al. Pathogenesis and clinical presentation of rosacea as a key for a symptom-oriented therapy. J Dtsch Dermatol Ges 2016;14(6):489-94.
Ehmann LM, Meller S, Homey B. Erfolgreiche Therapie einer granulomatösen Rosazea mit Dapson [Successful treatment of granulomatous rosacea with dapsone]. Hautarzt 2013;64(4):226-8.
Powell FC. Rosacea. In: Griffiths C, Barker J, Bleiker T, Chalmers R, Creamer D, editors. Rook's Textbook of Dermatology. 9th ed. Chichester, UK: Wiley Blackwell; 2016. p. 2409-22.
Almutairi RS, Al-Sabah HY. Facial granulomatous rosacea: A case report. Cureus 2023;15(9)
Kok WL, Oon HH, Giam YC. A case report of granulomatous rosacea of the face. Singapore Med J 2018;59(4):228-9.
Seo JI, Shin MK. Lupus miliaris disseminatus faciei versus granulomatous rosacea: A case report. Case Rep Dermatol 2021;13(2):321-9.
Tolaymat L, Hall MR. Perioral dermatitis. In: StatPearls [Internet]. Treasure Island: StatPearls Publishing; 2024.
Patil RM, Sardesai VR, Agarwal TD. Micropapular sarcoidosis. Clin Dermatol Rev 2019;3(1):104-5.
Slater N, Sathe NC, Rapini RP. Lupus miliaris disseminatus faciei. In: StatPearls [Internet]. Treasure Island: StatPearls Publishing; 2024.
Saal RC, Borda LJ, Hoffman ML, Roberts AA, Van Voorhees AS. Treatment of granulomatous rosacea with adalimumab. JAAD Case Rep 2023;40:89-91.
- Copyright of the article is transferred to the journal, by the knowledge of the author, whilst the moral right of the publication belongs to the author.
- The legal formal aspect of journal publication accessibility refers to Creative Commons Atribusi-Non Commercial-Share alike (CC BY-NC-SA), (https://creativecommons.org/licenses/by-nc-sa/4.0/)
- The articles published in the journal are open access and can be used for non-commercial purposes. Other than the aims mentioned above, the editorial board is not responsible for copyright violation
The manuscript authentic and copyright statement submission can be downloaded ON THIS FORM.