CORRELATION OF METABOLIC SYNDROME WITH GENU OSTEOARTHRITIS IN TYPE 2 DIABETES MELLITUS PATIENTS
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Abstract
Introduction: Osteoarthitisgenu is a joint disorder of the genu section due to a gradual decrease in cartilage bone cohesiveness. A metabolic syndrome is a group of both lipid and non-lipid abnormalities in an individual. This study aims to determine the relationship between metabolic syndrome and the incidence of osteoarthritis genu in type 2 DM patients at RSI Jemursari Surabaya.
Methods: This study uses an analytic observational method with a cross-sectional design. The population of type 2 DM patients and samples were obtained according to the inclusion and exclusion criteria. The sample size is 98 samples with a simple random sampling technique.
Result: In this study, the frequency of the metabolic syndrome in this study (31.6%), age 55-65 years (38.7%), male gender (51.6%), and components of the metabolic syndrome include hypertension, type 2 diabetes, hypertriglyceridemia (83.9%). On the frequency of Genu Osteoarthritis (28.6%) with the age of 46-55 years (43%), female gender (61%). Osteoarthritis genu location distribution is mostly bilateral (60.7%).
Conclusion: Based on the results of the Chi-Square Test statistical test using the SPSS statistical application, it shows a p significance value of 0.080 (> 0,05).
Keywords: Metabolic syndrome, Osteoarthritis genu, DM type 2
Bodhy, Widdy, and Aaltje E Manampiring. 2011. "PREVALENSI SINDROMA METABOLIK PADA REMAJA DI KOTA TOMOHON.” Universitas Sam Ratulanggi.
Courties, Alice, Jérémie Sellam, and Francis Berenbaum. 2017. "Metabolic Syndrome-Associated Osteoarthritis.” Current Opinion in Rheumatology 29(2): 214–22.
Eymard, F. et al. 2015. "Diabetes Is a Risk Factor for Knee Osteoarthritis Progression.” Osteoarthritis and Cartilage 23(6): 851–59.
Glyn-Jones, S et al. 2015. "Osteoarthritis.” The Lancet 386(9991): 376–87. https://www.sciencedirect.com/science/article/pii/S0140673614608023 (February 9, 2019).
Grundy, Scott M. 2018. "Metabolic Syndrome.” In Dallas: Center for Human Nutrition and Department of Internal MedicineUT Southwestern Medical Center, 71–107. http://link.springer.com/10.1007/978-3-319-44433-8_3.
Hasiibi, Wan. 2015. "Prevalensi Dan Distribusi Osteoartritis Lutut Berdasarkan Karakteristik Sosio-Demografi Dan Faktor Risiko Di Wilayah Kerja Puskesmas Susut I, Kecamatan Susut, Kabupaten Bangli Pada Tahun 2014.” Intisari Sains Medis 4(1): 32.
Hendrati, Lucia Yovita, and Niken Enestasia Anggraini. 2014. "Universitas Airlangga.” Hubungan Obesitas dan Faktor-Faktor Pada Individu dengan Kejadian Osteoarthritis Genu 2: 2014.
Huffman, K. M., and W. E. Kraus. 2012. "Osteoarthritis and the Metabolic Syndrome: More Evidence That the Etiology of OA Is Different in Men and Women.” Osteoarthritis and Cartilage 20(7): 603–4. http://dx.doi.org/10.1016/j.joca.2012.04.007.
Kamso, Sudijanto et al. 2016. "Prevalensi Dan Determinan Sindrom Metabolik Pada Kelompok Eksekutif Di Jakarta Dan Sekitarnya.” Kesmas: National Public Health Journal 6(2): 85.
Li, Hongxing, Daniel M George, Ruurd L Jaarsma, and Xinzhan Mao. 2016. "Metabolic Syndrome and Components Exacerbate Osteoarthritis Symptoms of Pain, Depression and Reduced Knee Function.” Annals of translational medicine 4(7): 133.
Nguyen, Tuan v. 2014. "Osteoarthritis in Southeast Asia.” International Journal of Clinical Rheumatology 9(5): 405–8. http://www.futuremedicine.com/doi/abs/10.2217/ijr.14.42.
PAPDI. 2014. Buku Ajar Ilmu Penyakit Dalam. 6th ed. eds. Siti Setiati, Idrus Alwi, Aru W Sudoyo, and Bambang Setiyohadi. Jakarta: Interna Publishing.
Rini, Sandra. 2015. "Sindrom Metabolik.” Jurnal Majority 4(4): 88–93.
Sellam, Jérémie, and Francis Berenbaum. 2013. "Is Osteoarthritis a Metabolic Disease?” Joint Bone Spine 80(6): 568–73.
Sherwood, L. 2012. Fisiologi Manusia Dari Sel Ke Sistem. 6th ed. Jakarta: EGC.
Wulandari, Mega Yuni, and Muhammad Atoillah Isfandiar. 2013. "Kaitan Sindroma Metabolik Dan Gaya Hidup Dengan Gejala Komplikasi Mikrovaskuler.” Jurnal Berkala Epidemiologi 1: 224–33.
Yanuarty, Maya. 2014. "Hubungan Antara Faktor Risiko Osteoartritis Lutut Dengannyeri, Disabilitas, Dan Berat Ringannyaosteoartritis.” Jurnal Media Medika Muda.
Zhuo, Qi, Wei Yang, Jiying Chen, and Yan Wang. 2012. "Metabolic Syndrome Meets Osteoarthritis.” Nature Reviews Rheumatology 8(12): 729–37.
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