Diagnostic Patterns of Suspected Covid-19 Patients Using Scor Covid-19, PCR Test and Serological Test in Dr. Soetomo Hospital Surabaya, Indonesia
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Objective: To find out the diagnostic pattern of COVID-19 using RT-PCR or a rapid antibody test in the suspected group of patients.
Method: The study was conducted in Dr. Soetomo General Hospital (referral hospital for covid-19, 1500 beds). The study used data on patients with suspected covid-19 who were hospitalized at the Dr. Soetomo General Hospital in Surabaya.
Result: There were 200 suspected COVID-19 patients enrolled in this study, the main complaints of cough, fever, dyspnoea, around 69.5%, 75%, and 76.5%, respectively. Although not a common symptom, it seems that anosmia (14%) is typical for COVID-19. Based on this scoring system, a total of 196 patients had a high risk of being infected with COVID-19, and 125 (64%) of them finally showed a positive PCR test. PCR test mostly positive (62.5%), while serological test (rapid immunoglobulin test) mostly nonreactive, but there were no significant differences between PCR and Serological test (p=0.16 OR: 1.5(0.84-71). Furthermore, if we compare the various existing variables, namely the covid-19 score, immunoglobulin rapid test, and radiological examination, only the radiological examination results can be used as a strong predictor of positive PCR results (p=0.005, OR: 1.68 (0.17-16.43).
In this study, we found that abnormal chest radiographs are a good parameter for diagnosing COVID-19, (OR: 2.92; 95% CI, 1.34 -6.34).
Conclusion: The initial radiological examination combined with the clinical symptoms of Covid-19 is the most important thing to predict the presence of this disease.World Health Organization (WHO-A). Clinical management of severe acute respiratory infection (SARI) when Covid-19 disease is suspected: interim guidence, 13 March 2020.
Salehi S, Abedi A, Balakrishnan S, Gholamrezanezhad A. Coronavirus Disease 2019 (COVID-19): A Systematic Review of Imaging Findings in 919 Patients. AJR Am J Roentgenol. 2020:1-7.
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497-5
Yang X, Yu Y, Xu J, Shu H, Xia J, Liu H, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med. 2020; published online March 15. DOI: 10.13140/RG.2.2.28124.74882.
World Health Organization (WHO-B). Laboratory testing for coronavirus disease 2019 (COVID-19) in suspected human cases. Geneva: World Health Organization; 2020.
Riccò, M.; Ferraro, P.; Gualerzi, G.; Ranzieri, S.; Henry, B.M.; Said, Y.B.; Pyatigorskaya, N.V.; Nevolina, E.; Wu, J.; Bragazzi, N.L.; Signorelli, C. Point-of-Care Diagnostic Tests for Detecting SARS-CoV-2 Antibodies: A Systematic Review and Meta-Analysis of Real-World Data. J Clin Med 2020, 9, 1515. doi:10.3390/jcm9051515.
Bastos, M.L.; Tavaziva, G.; Abidi, S.K.; Campbell, J.R.; Haraoui, L.P.; Johnston, J.C.; Lan, Z.; Law, S.; MacLean, E.; Trajman, A.; Menzies, D.; Benedetti, A.; Khan, F.A. Diagnostic accuracy of serological tests for covid-19: systematic review and meta-analysis. BMJ 2020, p. m2516. doi:10.1136/bmj.m2516.
Wong, H.Y.F.; Lam, H.Y.S.; Fong, A.H.T.; Leung, S.T.; Chin, T.W.Y.; Lo, C.S.Y.; Lui, M.M.S.; Lee, J.C.Y.; Chiu, K.W.H.; Chung, T.; others. Frequency and distribution of chest radiographic findings in COVID-19 positive patients. Radiology 2020, p. 201160.
Schiaffino, S.; Tritella, S.; Cozzi, A.; Carriero, S.; Blandi, L.; Ferraris, L.; Sardanelli, F. Diagnostic Performance of Chest X-Ray for COVID-19 Pneumonia During the SARS-CoV-2 Pandemic in Lombardy, Italy. J Thorac Imaging 2020, 35, W105–W106. doi:10.1097/rti.0000000000000533.
Shi H, Han X, Jiang N, Cao Y, Alwalid O, Gu J, et al. Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study. Lancet Infect Dis. 2020; published
Greenhalgh, T.; Thompson, P.; Weiringa, S.; Neves, A.L.; Husain, L.; Dunlop, M.; Rushforth, A.; Nunan, D.; de Lusignan, S.; Delaney, B. What items should be included in an early warning score for remote assessment of suspected COVID-19? qualitative and Delphi study. BMJ Open 2020, 10, e042626. doi:10.1136/bmjopen-2020-042626.
Jacobi, A.; Chung, M.; Bernheim, A.; Eber, C. Portable chest X-ray in coronavirus disease-19 (COVID-19): A pictorial review. Clin Imaging 2020, 64, 35–42. doi:10.1016/j.clinimag.2020.04.001.
Aljondi, R.; Alghamdi, S. Diagnostic Value of Imaging Modalities for COVID-19: Scoping Review. J Med Internet Res 2020, 22, e19673. doi:10.2196/19673.
Bhaskar, S.; Ali, Z.; Goneppanavar, U.; Dongare, P.; Garg, R.; Kannan, S.; Harsoor, S. Development of a preoperative Early Warning Scoring System to identify highly suspect COVID-19 patients. J Anaesthesiol Clin Pharmacol 2020, 36, 62. doi:10.4103/joacp.joacp_274_20
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