Main Article Content

Abstract

Highlights:



  1. Rare occurrence of a large, well-differentiated primary renal neuroendocrine tumor in a young man.

  2. Identifying primary renal NET from the workup and histological examination of renal tumors needs to be done to understand more of this infrequent type of tumor.


 


Abstract:


Neuroendocrine Tumors (NETs) are a diverse range of neoplasms with various biological and histologic features and therapeutic responses. The prevalence of primary renal carcinoids is scarce worldwide. At the moment, complete surgical resection is the primary treatment against primary neuroendocrine tumors of the kidney. Nephrectomy followed by the lymph node dissection is a standard procedure for localized primary renal NETs. Since renal carcinoid tumor is extremely rare, we decided to present a unique case of a 25-years-old male with neuroendocrine renal carcinoid tumor following radical nephrectomy. The results indicated a solid, solitary tumor verified on the frozen section because a postoperative CT–scan showed a recurring mass in the renal fossa following radical nephrectomy. The case emphasized the need to investigate primary renal NET in the workup and histological examination of renal tumors and also contributed to our understanding of this infrequent clinical entity.

Keywords

Neuroendocrine Tumors NETs Carcinoid Tumor Radical Nephrectomy Case Report

Article Details

How to Cite
Ishaq, M. R., Febriansyah, N. A., & Soetojo, S. (2022). A Rare Case of Neuroendocrine Tumor Following Radical Nephrectomy. Folia Medica Indonesiana, 58(2), 192–194. https://doi.org/10.20473/fmi.v58i2.33283

References

  1. Bégin L, Guy L, Jacobson S, et al (1998). Renal carcinoid and horseshoe kidney: A frequent association of two rare entities--a case report and review of the literature. J. Surg. Oncol. 68, 113–119.
  2. Jain D, Sharma M, Singh K, et al (2010). Primary carcinoid tumor of the kidney: Case report and brief review of literature. Indian J. Pathol. Microbiol. 53, 772–774.
  3. Kawajiri H, Onoda N, Ohira M, et al (2004). Carcinoid tumor of the kidney presenting as a large abdominal mass: Report of a case. World J. Surg. Oncol. 34, 86–89.
  4. Kim J, Suh K (2004). Primary carcinoid tumor in a mature teratoma of the kidney: Ultrasonographic and computed tomographic findings. J. Ultrasound Med. 23, 433–437.
  5. Klimstra D, Modlin I, Coppola D, et al (2010). The pathologic classification of neuroendocrine tumors: A review of nomenclature, grading, and staging systems. Pancreas 39, 707–712.
  6. Korkmaz T, Seber S, Yavuzer D, et al (2013). Primary renal carcinoid: Treatment and prognosis. Crit. Rev. Oncol. Hematol. 87, 256–264.
  7. Krishnan B, Truong L, Saleh D, et al (1997). Horseshoe kidney is associated with an increased relative risk of primary renal carcinoid tumor. J. Urol. 157, 2059–2066.
  8. Kuba M, Wasserman A, Vnencak-Jones C, et al (2017). Primary carcinoid tumor of the renal pelvis arising from intestinal metaplasia: An unusual histogenetic pathway? Appl. Immunohistochem. Mol. Morphol. 25, 49–57.
  9. Kurzer E, Leveille R, Morillo G (2005). Rare case of carcinoid tumor arising within teratoma in kidney. Urology 66, 5–6.
  10. Lane B, Chery F, Jour G, et al (2007). Renal neuroendocrine tumours: A clinicopathological study. BJU Int. 100, 1030–1035.
  11. Litwinowicz R, Szpor J, Januś G, et al (2011). Primary carcinoid tumour in horseshoe kidney. Int. J. Urol. 62, 72–74.
  12. Lodding P, Hugosson J, Hansson G (1997). Primary carcinoid tumour with ossification masquerading as calyx stone in a horseshoe kidney. Scand. J. Urol. Nephrol. 31, 575–578.
  13. Martignoni G, Eble J (2003). Carcinoid tumors of the urinary bladder. Immunohistochemical study of 2 cases and review of the literature. Arch. Pathol. Lab. Med. 127, 22–24.
  14. Murali R, Kneale K, Lalak N, et al (2006). Carcinoid tumors of the urinary tract and prostate. Arch. Pathol. Lab. Med. 130, 1693–1706.
  15. Okoń K (2008). Pathology of renal tumors in adults. Molecular biology, histopathological diagnosis and prognosis. Polish J. Pathol. 59, 129–176.
  16. Rodríguez-Covarrubias F, Gómez X, Valerio J, et al (2007). Carcinoid tumor arising in a horseshoe kidney. Int. Urol. Nephrol. 39, 373–376.
  17. Romero F, Rais-Bahrami S, Permpongkosol S, et al (2006). Primary carcinoid tumors of the kidney. Adv. Urol. 176, 2359–2366.
  18. Rudrick B, Nguyen G, Lakey W (1995). Carcinoid tumor of the renal pelvis: Report of a case with positive urine cytology. Diagn. Cytopathol. 12, 360–363.
  19. Shurtleff B, Shvarts O, Rajfer J (2005). Primary carcinoid tumour of the kidney. A case report and review of the literature. Adv. Urol. 7, 229–233.