Main Article Content
Abstract
Highlights:
- Sarcopenia can cause deleterious effects on patients.
- The Asian Working Group for Sarcopenia (AWGS) and the European Working Group on Sarcopenia in Older People (EWGSOP) provide the most widely used criteria to diagnose sarcopenia.
- Knowledge of sarcopenia should be a trigger for clinicians and surgeons to evaluate the treatment plan and anticipate the implications experienced by the patients.
Abstract:
Sarcopenia is a condition of low muscle strength, mass, and low physical performance that is affected by age (primary sarcopenia) and one or combination of systemic diseases, physical inactivity, and insufficient intake of energy (secondary sarcopenia). This condition affects one in ten healthy adults aged ≥60 years. There are two widely used criteria to diagnose sarcopenia, the Asian Working Group for Sarcopenia (AWGS) and the European Working Group on Sarcopenia in Older People (EWGSOP). These working groups created algorithms to facilitate the diagnosis. Establishing the diagnosis is crucial because it has deleterious impacts on patients, such as increasing risks of mortality, morbidity, falls, complications during and after surgery, disability, prolonged hospitalization, and fractures. Sarcopenia is considered an independent mortality risk. It is paramount for physicians to assess this condition before treating the patients because it can predict the risk and plan better treatment options to achieve better outcomes. Early assessment is crucial, even for surgeons. Sarcopenia also negatively impacts patients who had surgery. Up to 44% patients who underwent orthopedic trauma surgery had sarcopenia. The high percentage was affected by the increased risk of falls and fractures. On that account, this condition needs to be treated. The main treatments for this condition are exercise dan adequate nutrition intake. The recommended exercise as a first-line treatment is resistance or strength training. Overall, knowledge on sarcopenia can prepare clinicians and surgeons in anticipating the implications of sarcopenia.
Keywords
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References
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- Arango-Lopera VE, Arroyo P, Gutiérrez-Robledo LM, et al (2013). Mortality as an adverse outcome of sarcopenia. J Nutr Health Aging 17, 259–62.
- Atala NA, Bongiovanni SL, Galich AM, et al (2021). Is sarcopenia a risk factor for rotator cuff tears? J Shoulder Elb Surg 30, 1851–5.
- Barbosa-Silva TG, Menezes AMB, Bielemann RM, et al (2016). Enhancing SARC-F: Improving sarcopenia screening in the clinical practice. J Am Med Dir Assoc 17, 1136–41.
- Chen L-K, Woo J, Assantachai P, et al (2020). Asian working group for sarcopenia: 2019 consensus update on sarcopenia diagnosis and treatment. J Am Med Dir Assoc 21, 300-307.e2.
- Chen Y, Kuo Y, Hung S, et al (2021). Loss of skeletal muscle mass can be predicted by sarcopenia and reflects poor functional recovery at one year after surgery for geriatric hip fractures. Injury 52, 3446–52.
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- Cruz-Jentoft AJ, Bahat G, Bauer J, et al (2019b). Sarcopenia : revised European consensus on definition and diagnosis. Age Ageing 48, 16–31.
- Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al (2010). Sarcopenia: European consensus on definition and diagnosis. Report of the European working group on sarcopenia in older people.
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- Frontera WR, Rodriguez Zayas A, Rodriguez N (2012). Aging of human muscle: Understanding sarcopenia at the single muscle cell level. Phys Med Rehabil Clin N Am 23, 201–7.
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- Hurst C, Robinson SM, Witham MD, et al (2022). Resistance exercise as a treatment for sarcopenia: Prescription and delivery. Age Ageing 51, 1–10.
- Iijima H, Aoyama T (2021). Increased recurrent falls experience in older adults with coexisting of sarcopenia and knee osteoarthritis: A cross-sectional study. BMC Geriatr 21, 698.
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- Landi F, Liperoti R, Russo A, et al (2012). Sarcopenia as a risk factor for falls in elderly individuals: Results from the ilSIRENTE study. Clin Nutr 31, 652–8.
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- Tarantino U, Piccirilli E, Fantini M, et al (2015). Sarcopenia and fragility fractures: Molecular and clinical evidence of the bone-muscle interaction. J Bone Jt Surg 97, 429–37.
- Tieland M, Trouwborst I, Clark BC (2018). Skeletal muscle performance and ageing. J Cachexia Sarcopenia Muscle 9, 3–19.
- Wahlen BM, Mekkodathil A, Al-Thani H, et al (2020). Impact of sarcopenia in trauma and surgical patient population: A literature review. Asian J Surg 43, 647–53.
- Widajanti N, Ichwani J, Dharmanta RS, et al (2020). Sarcopenia and frailty profile in the elderly community of surabaya: A descriptive study. Acta Med Indones 52, 5–13.
- Xia L, Zhao R, Wan Q, et al (2020). Sarcopenia and adverse health"related outcomes: An umbrella review of meta"analyses of observational studies. Cancer Med 9, 7964–78.
- Yeung SSY, Reijnierse EM, Pham VK, et al (2019). Sarcopenia and its association with falls and fractures in older adults: A systematic review and meta"analysis. J Cachexia Sarcopenia Muscle 10, 485–500.
- Yoo J, Chung HJ, Kim BG, et al (2021). Comparative analysis of the association between various serum vitamin D biomarkers and sarcopenia. J Clin Lab Anal 35, 1–9.
- Yoshimura Y, Wakabayashi H, Nagano F, et al (2022). Chair-stand exercise improves sarcopenia in rehabilitation patients after stroke. Nutrients 14, 461.
References
Anker SD, Morley JE, Haehling S (2016). Welcome to the ICD"10 code for sarcopenia. J Cachexia Sarcopenia Muscle 7, 512–4.
Arango-Lopera VE, Arroyo P, Gutiérrez-Robledo LM, et al (2013). Mortality as an adverse outcome of sarcopenia. J Nutr Health Aging 17, 259–62.
Atala NA, Bongiovanni SL, Galich AM, et al (2021). Is sarcopenia a risk factor for rotator cuff tears? J Shoulder Elb Surg 30, 1851–5.
Barbosa-Silva TG, Menezes AMB, Bielemann RM, et al (2016). Enhancing SARC-F: Improving sarcopenia screening in the clinical practice. J Am Med Dir Assoc 17, 1136–41.
Chen L-K, Woo J, Assantachai P, et al (2020). Asian working group for sarcopenia: 2019 consensus update on sarcopenia diagnosis and treatment. J Am Med Dir Assoc 21, 300-307.e2.
Chen Y, Kuo Y, Hung S, et al (2021). Loss of skeletal muscle mass can be predicted by sarcopenia and reflects poor functional recovery at one year after surgery for geriatric hip fractures. Injury 52, 3446–52.
Cruz-Jentoft AJ, Bahat G, Bauer J, et al (2019a). Sarcopenia: Revised European consensus on definition and diagnosis. Age Ageing 48, 16–31.
Cruz-Jentoft AJ, Bahat G, Bauer J, et al (2019b). Sarcopenia : revised European consensus on definition and diagnosis. Age Ageing 48, 16–31.
Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al (2010). Sarcopenia: European consensus on definition and diagnosis. Report of the European working group on sarcopenia in older people.
Deren ME, Babu J, Cohen EM, et al (2017). Increased mortality in elderly patients with sarcopenia and acetabular fractures. J Bone Jt Surg 99, 200–6.
Friedman J, Lussiez A, Sullivan J, et al (2015). Implications of sarcopenia in major surgery. Nutr Clin Pract 30, 175–9.
Frontera WR, Rodriguez Zayas A, Rodriguez N (2012). Aging of human muscle: Understanding sarcopenia at the single muscle cell level. Phys Med Rehabil Clin N Am 23, 201–7.
Han D, Wu W, Hsu P, et al (2021). Sarcopenia is associated with increased risks of rotator cuff tendon diseases among community-dwelling elders: A cross-sectional quantitative ultrasound study. Front Med.
Hurst C, Robinson SM, Witham MD, et al (2022). Resistance exercise as a treatment for sarcopenia: Prescription and delivery. Age Ageing 51, 1–10.
Iijima H, Aoyama T (2021). Increased recurrent falls experience in older adults with coexisting of sarcopenia and knee osteoarthritis: A cross-sectional study. BMC Geriatr 21, 698.
Ji H, Won Y-Y, Kang BM, et al (2014). Sarcopenia in patients scheduled to undergo orthopaedic surgery. In European Calcified Tissue Society Congress. bioscientifica, Prague, Czech Republic.
Landi F, Liperoti R, Russo A, et al (2012). Sarcopenia as a risk factor for falls in elderly individuals: Results from the ilSIRENTE study. Clin Nutr 31, 652–8.
Laubscher C V., Burger MC, Conradie MM, et al (2020). Prevalence of sarcopenia in older South African patients following surgery for fragility fractures of the hip. Geriatr Orthop Surg Rehabil 11.
Mitchell WK, Williams J, Atherton P, et al (2012). Sarcopenia, dynapenia, and the impact of advancing age on human skeletal muscle size and strength: A quantitative review. Front Physiol 3, 1–18.
Otsuka Y, Yamada Y, Maeda A, et al (2022). Effects of resistance training intensity on muscle quantity/quality in middle"aged and older people: A randomized controlled trial. J Cachexia Sarcopenia Muscle 13, 894–908.
Park S, Kim HJ, Ko BG, et al (2016). The prevalence and impact of sarcopenia on degenerative lumbar spinal stenosis. Bone Joint J 98-B, 1093–8.
Petermann"Rocha F, Balntzi V, Gray SR, et al (2022). Global prevalence of sarcopenia and severe sarcopenia: A systematic review and meta"analysis. J Cachexia Sarcopenia Muscle 13, 86–99.
Petermann"Rocha F, Ferguson LD, Gray SR, et al (2021). Association of sarcopenia with incident osteoporosis: A prospective study of 168,682 UK biobank participants. J Cachexia Sarcopenia Muscle 12, 1179–88.
Rosenberg IH (1997). Sarcopenia: Origins and clinical relevance. J Nutr 127, 990S-991S.
Shafiee G, Keshtkar A, Soltani A, et al (2017). Prevalence of sarcopenia in the world: A systematic review and meta- analysis of general population studies. J Diabetes Metab Disord 16, 21.
Shen Y, Liu D, Li S, et al (2022). Effects of exercise on patients important outcomes in older people with sarcopenia: An umbrella review of meta-analyses of randomized controlled trials. Front Med 9, 1–9.
Tarantino U, Piccirilli E, Fantini M, et al (2015). Sarcopenia and fragility fractures: Molecular and clinical evidence of the bone-muscle interaction. J Bone Jt Surg 97, 429–37.
Tieland M, Trouwborst I, Clark BC (2018). Skeletal muscle performance and ageing. J Cachexia Sarcopenia Muscle 9, 3–19.
Wahlen BM, Mekkodathil A, Al-Thani H, et al (2020). Impact of sarcopenia in trauma and surgical patient population: A literature review. Asian J Surg 43, 647–53.
Widajanti N, Ichwani J, Dharmanta RS, et al (2020). Sarcopenia and frailty profile in the elderly community of surabaya: A descriptive study. Acta Med Indones 52, 5–13.
Xia L, Zhao R, Wan Q, et al (2020). Sarcopenia and adverse health"related outcomes: An umbrella review of meta"analyses of observational studies. Cancer Med 9, 7964–78.
Yeung SSY, Reijnierse EM, Pham VK, et al (2019). Sarcopenia and its association with falls and fractures in older adults: A systematic review and meta"analysis. J Cachexia Sarcopenia Muscle 10, 485–500.
Yoo J, Chung HJ, Kim BG, et al (2021). Comparative analysis of the association between various serum vitamin D biomarkers and sarcopenia. J Clin Lab Anal 35, 1–9.
Yoshimura Y, Wakabayashi H, Nagano F, et al (2022). Chair-stand exercise improves sarcopenia in rehabilitation patients after stroke. Nutrients 14, 461.