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Submitted
23 January 2024
Accepted
17 April 2024
Published
10 March 2024
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Abstract

Highlights:
1. A questionnaire, comprising various risk factors associated with food allergies, is anticipated to provide reliable indications for determining the necessity of restrictive diets for patients within primary healthcare settings.
2. Over time, the findings of this study can facilitate the development of a streamlined and cost-effective diagnostic tool, which will be particularly beneficial in remote regions due to its practical and efficient means of identifying food allergies.


Abstract
In Gresik, Indonesia, limited resources have led to challenges in accurately diagnosing food allergies. This study aimed to identify risk factors for food allergies among children in Gresik using a questionnaire-based approach. The study's ultimate goal was to develop a simple diagnostic tool in primary healthcare settings. Conducted at Petrokimia Gresik Hospital, this cross-sectional study enrolled children aged ≥6 months experiencing respiratory symptoms or atopic dermatitis for ≥1 week. The subjects (n = 247) underwent a two- to four-week restrictive diet for diagnostic purposes. The questionnaire demonstrated validity and reliability. Bivariate statistical analyses were performed to examine the correlations between risk factors and the incidence of food allergies (p < 0.05). A receiver operating characteristic (ROC) curve analysis was used to establish the cut-off values for the number of food allergies and atopic family members. The majority of the 247 children enrolled in this study were 6 to 12 years old. Respiratory symptoms (56.3%) were more common than atopic dermatitis (38.1%). The significant risk factors for food allergies included atopic dermatitis (p = 0.001; R = 0.203), previous history of suspected food allergies (p < 0.001; R = 0.747), and atopy in the family (p = 0.013; R = 0.157). The ROC curve analysis established the cut-off values for the number of atopic family members at 1.5 (p = 0.005; 95% CI 0.53-0.67) and the number of food allergies at 0.5 (p = 0.000; 95% CI 0.85-0.94). In conclusion, children are considered at risk of food allergies if they display persistent respiratory symptoms or atopic dermatitis, considering the history of suspected food allergies even to only one specific type of food.

Keywords

Food allergy atopic dermatitis chronic respiratory diseases questionnaire health risks

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How to Cite
Natalia Erica Jahja, Zahrah Hikmah, Azwin Mengindra Putera, & Anang Endaryanto. (2024). Preliminary Investigation of Risk Factors for Food Allergies in the Pediatric Population: Observations from a Survey Utilizing a Simplified Questionnaire in Gresik, East Java, Indonesia. Folia Medica Indonesiana, 60(1), 61–68. https://doi.org/10.20473/fmi.v60i1.53175
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References

  1. Al-Adawiyah R, Putera AM, Astari L, et al. (2021). Determinant factors of recurrence atopic dermatitis symptoms in children: A cross-sectional study. Annals of Medicine and Surgery 70, 102847. doi: 10.1016/j.amsu.2021.102847.
  2. Allen KJ, Koplin JJ (2019). What can urban/rural differences in food allergy prevalence tell us about the drivers of food allergy? Journal of Allergy and Clinical Immunology 143, 554–556. doi: 10.1016/j.jaci.2018.10.055.
  3. Baker MG, Nowak-Wegrzyn A (2020). Food allergy prevention: current evidence. Current Opinion in Clinical Nutrition & Metabolic Care 23, 196–202. doi: 10.1097/MCO.0000000000000651.
  4. Botha M, Basera W, Facey-Thomas HE, et al (2019). Nutrition and allergic diseases in urban and rural communities from the South African Food Allergy cohort. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 30, 511–521. doi: 10.1111/pai.13058.
  5. Devdas JM, Mckie C, Fox AT, et al (2018). Food allergy in children: An overview. The Indian Journal of Pediatrics 85, 369–374. doi: 10.1007/s12098-017-2535-6.
  6. Dzakiyyah SA, Endaryanto A, Dewanti L, et al (2022). Second-hand smoke and early allergic manifestation in children. Jurnal Respirasi 8, 126–132. doi: 10.20473/jr.v8-I.3.2022.126-132.
  7. Halken S, Muraro A, de Silva D, et al (2021). EAACI guideline: Preventing the development of food allergy in infants and young children (2020 update) ed. Kalaycı í–. Pediatric Allergy and Immunology 32, 843–858. doi: 10.1111/pai.134 96.
  8. Hoehn JL, Dahlquist LM, Hahn AL, et al (2016). Parents of children with food allergy: Gender differences in perceived impact and perceived food allergy severity. Journal of Pediatric Psychology, 59. doi: 10.1093/jpepsy/jsw059.
  9. IBM Corp (2023). IBM SPSS Statistics for Windows, Version 29.0. Armonk, NY: IBM Corp. Available at: https://www.ibm.com/id-id/products /spss-statistics.
  10. Kalach N, Bellaí¯che M, Elias-Billon I, et al (2019). Family history of atopy in infants with cow's milk protein allergy: A French population-based study. Archives de Pédiatrie 26, 226–231. doi: 10.1016/j.arcped.2019.02.014.
  11. Kummeling I, Thijs C, Stelma F, et al. (2006). Do parents with an atopic family history adopt a ‘prudent' lifestyle for their infant? (KOALA Study). Clinical & Experimental Allergy 36, 489–494. doi: 10.1111/j.1365-2222.2006.02473.x.
  12. Levin ME, Botha M, Basera W, et al (2020). Environmental factors associated with allergy in urban and rural children from the South African Food Allergy (SAFFA) cohort. Journal of Allergy and Clinical Immunology 145, 415–426. doi: 10.1016/j.jaci.2019.07.048.
  13. Mastrorilli C, Caffarelli C, Hoffmann"Sommergruber K (2017). Food allergy and atopic dermatitis: Prediction, progression, and prevention. Pediatric Allergy and Immunology 28, 831–840. doi: 10.1111/pai.12831.
  14. Putera AM, Octaviana DS, Gunawan F, et al (2023). Holistic management of pediatric patients with asthma through the family medicine approach: A case series. Jurnal Respirasi 9, 229–236. doi: 10.20473/jr.v9-I.3.2023.229-236.
  15. Putera AM, Ramadhianty L (2023). Factors determining course of IgE-mediated cow's milk allergy. Indian Journal of Pediatrics. doi: 10.1007/s12098-023-04917-x.
  16. Renz H, Allen KJ, Sicherer SH, et al. (2018). Food allergy. Nature Reviews Disease Primers 4, 17098. doi: 10.1038/nrdp.2017.98.
  17. Sacchetti M, Baiardini I, Chini L, et al (2017). Development and preliminary validation of a new screening questionnaire for identifying atopic children. Pediatric Health, Medicine and Therapeutics 8, 99–105. doi: 10.2147/PHMT.S14 2271.
  18. Saito-Abe M, Yamamoto-Hanada K, Pak K, et al (2022). How a family history of allergic diseases influences food allergy in children: The Japan environment and children's study. Nutrients 14, 4323. doi: 10.3390/nu14204323.
  19. Salsabila HY, Putera AM, Baskoro A (2021). Correlation between nutritional status and children's activity with food allergy: A cross-sectional study. Annals of Medicine & Surgery. doi: 10.1016/j.amsu.2021.102652.
  20. Skjerven HO, Lie A, Vettukattil R, et al (2022). Early food intervention and skin emollients to prevent food allergy in young children (PreventADALL): a factorial, multicentre, cluster-randomised trial. The Lancet 399, 2398–2411. doi: 10.1016/S0140-6736(22)00687-0.
  21. Statistics Gresik (2023). Gresik Regency in 2023. Stat Gresik. Available at: https://gresikkab.bps.go. id/publication/2023/02/28/505807589f05a5fb25f8c544/kabupaten-gresik-dalam-angka-2023.html.
  22. Sulistyandari U (2019). Air pollution impact assessment of Gresik Industrial Area (KIG) based on neighborhood community in Gresik District. International International Journal of Engineering Research and Technology. doi: 10.17577/IJERTV 8IS070287.
  23. Tsang S, Royse C, Terkawi A (2017). Guidelines for developing, translating, and validating a questionnaire in perioperative and pain medicine. Saudi Journal of Anaesthesia 11, 80. doi: 10.4103/sja.SJA_203_17.
  24. Wang X, Cheng Z (2020). Cross-sectional studies: Strengths, weaknesses, and recommendations. Chest 158, S65–S71. doi: 10.1016/j.chest.2020.03. 012.
  25. Wu TC, Tsai TC, Huang CF, et al (2012). Prevalence of food allergy In Taiwan: A questionnaire-based survey. Internal Medicine Journal 42, 1310–1315. doi: 10.1111/j.1445-5994.2012.02820.x.
  26. Yang L, Fu J, Zhou Y (2020). Research progress in atopic march. Frontiers in Immunology 11. doi: 10.3389/fimmu.2020.01907.
  27. Zhang Z (2016). Univariate description and bivariate statistical inference: the first step delving into data. Annals of Translational Medicine 4, 91–91. doi: 10.21037/atm.2016.02.11.