HEALTH RISK ASSESSMENT OF PESTICIDE EXPOSURE IN FARMERS AROUND RICE FARMING AREA IN OGAN ILIR REGENCY, SOUTH SUMATRA, INDONESIA
Introduction: Pesticides are chemical compounds that are toxic to the environment and humans. Approximately 89.8% of farmers in South Sumatra use chemical pesticides. Aims: This study aims to analyze the health risks due to pesticide exposure among farmers residing in rice farming areas. Methods: This study used an analytical observational design with a cross-sectional approach and was conducted in Pemulutan Subdistrict, Ogan Ilir Regency, from October 2020 to January 2021. The sample size consisted of 61 randomly selected respondents. Blood test samples were taken and examined at the Palembang Health Laboratory Center. The cholinesterase was examined using the DGKC colorimetric (KINETIC) method. Independent t-test and multiple linear regression test were used to analyze the data. Results: The results of the analysis showed that the average cholinesterase level in the blood serum of the farmers was 7628.40 U/L. This study also found that 83.6% of the farmers did not use complete and standard personal protective equipment. The variables that were significantly associated with cholinesterase levels in the blood of the farmers were age group and length of farming. Length of farming was identified as a predictor variable. Conclusion: Pesticides used by farmers in rice farming areas vary widely, ranging from slightly to extremely hazardous. Although the cholinesterase levels in farmers are in the normal range, they can increase over a long period of time. The length of farming is a predictor of cholesterol levels in farmers.
Arisekar, U., Jeya Shakila, R., Shalini, R., & Jeyasekaran, G. (2021). Pesticides Contamination in the Thamirabarani, A Perennial River in Peninsular India: The First Report on Ecotoxicological and Human Health Risk Assessment. Chemosphere, 267, 129251. https://doi.org/https://doi.org/10.1016/j.chemosphere.2020.129251
As' ady, B. J. A., Supangat, S., & Indreswari, L. (2019). Analysis of Personal Protective Equipments Pesticides Usage Effects on Health Complaints of Farmers in Pringgondani Village Sumberjambe District Jember Regency. Journal of Agromedicine and Medical Sciences, 5(1), 31–38. https://doi.org/https://doi.org/10.19184/ams.v5i1.7901
Barrón Cuenca, J., Tirado, N., Vikström, M., Lindh, C. H., Stenius, U., Leander, K., Berglund, M., & Dreij, K. (2020). Pesticide Exposure among Bolivian Farmers: Associations between Worker Protection and Exposure Biomarkers. Journal of Exposure Science & Environmental Epidemiology, 30(4), 730–742. https://doi.org/https://doi.org/10.1038/s41370-019-0128-3
Benitez, A., & Ramírez-Vargas, M. A. (2021). Cholinesterase as a Biomarker to Identify Cases of Pesticide poisoning. Mexican Journal of Medical Research ICSA, 9(17), 47–55. https://doi.org/https://doi.org/10.29057/mjmr.v9i17.5577
Bhuiyan, M. A. H., Rahman, M. H., Uddin, M. A., Chowdhury, M. A. Z., Rahman, M. A., Saha, B. B., & Didar-Ul Islam, S. M. (2021). Contamination of Pond and Canal Water by Residues of Organophosphorus and Carbamate Pesticides in Feni District, Bangladesh. Environmental Sustainability, 4(1), 191–197. https://doi.org/10.1007/s42398-021-00161-1
Carvalho, F. P. (2017). Pesticides, Environment, and Food Safety. Food and Energy Security, 6(2), 48–60. https://doi.org/https://doi.org/10.1002/fes3.108
Cotton, J., Edwards, J., Rahman, M. A., & Brumby, S. (2018). Cholinesterase Research Outreach Project (CROP): Point Of Care Cholinesterase Measurement In An Australian Agricultural Community. Environmental Health, 17(1), 1–11. https://doi.org/https://doi.org/10.1186/s12940-018-0374-1
Damalas, C. A., & Koutroubas, S. D. (2016). Farmers' Exposure to Pesticides: Toxicity Types and Ways of Prevention. Toxics, 4(1), 1–10. https://doi.org/https://doi.org/10.3390/toxics4010001
Dereumeaux, C., Fillol, C., Quenel, P., & Denys, S. (2020). Pesticide Exposures for Residents Living Close to Agricultural Lands: A review. Environment International, 134, 105210. https://doi.org/https://doi.org/10.1016/j.envint.2019.105210
Directorate of Fertilizers and Pesticides. (2016). Agriculture and Forestry Pesticides in 2016 (pp. 1–905). Directorate General of Agricultural Infrastructure and Facilities.
IRIS Assessments | IRIS | US EPA, (2017).
Gupta, P. K. (2019). Toxic Effects of Pesticides and Agrochemicals. In Concepts and Applications in Veterinary Toxicology (pp. 59–82). Springer. https://doi.org/https://doi.org/10.1201/9781003000358-10
Gupta, R. C., Miller Mukherjee, I. R., Doss, R. B., Malik, J. K., & Milatovic, D. (2017). Chapter 35 - Organophosphates and Carbamates. In R. C. Gupta (Ed.), Reproductive and Developmental Toxicology (Second Edition) (Second Edi, pp. 609–631). Academic Press. https://doi.org/https://doi.org/10.1016/B978-0-12-804239-7.00035-4
Guytingco, A., Thepaksorn, P., & Neitzel, R. L. (2018). Prevalence Of Abnormal Serum Cholinesterase and Associated Symptoms From Pesticide Exposure Among Agricultural Workers in The South Of Thailand. Journal of Agromedicine, 23(3), 270–278. https://doi.org/https://doi.org/10.1080/1059924X.2018.1470049
Hinson, A. V., Lokossou, V. K., Schlünssen, V., Agodokpessi, G., Sigsgaard, T., & Fayomi, B. (2016). Cotton Dust Exposure and Respiratory Disorders amongTextile Workers at a Textile Company in the Southern Part of Benin. International Journal of Environmental Research and Public Health, 13(9), 895. https://doi.org/https://doi.org/10.3390/ijerph13090895
Joko, T., Dewanti, N. A. Y., & Dangiran, H. L. (2020). Pesticide Poisoning and the Use of Personal Protective Equipment (PPE) in Indonesian Farmers. Journal of Environmental and Public Health, 2020, 5379619. https://doi.org/10.1155/2020/5379619
Kapeleka, J. A., Sauli, E., Sadik, O., & Ndakidemi, P. A. (2019). Biomonitoring of Acetylcholinesterase (AChE) Activity among Smallholder Horticultural Farmers Occupationally Exposed to Mixtures of Pesticides in Tanzania. Journal of Environmental and Public Health, 2019, 3084501. https://doi.org/10.1155/2019/3084501
Kapsi, M., Tsoutsi, C., Paschalidou, A., & Albanis, T. (2019). Environmental Monitoring and Risk Assessment of Pesticide Residues in Surface Waters of the Louros River (N.W. Greece). Science of The Total Environment, 650, 2188–2198. https://doi.org/https://doi.org/10.1016/j.scitotenv.2018.09.185
Kim, K.-H., Kabir, E., & Jahan, S. A. (2017). Exposure to Pesticides and the Associated Human Health Effects. Science of the Total Environment, 575, 525–535. https://doi.org/https://doi.org/10.1016/j.scitotenv.2016.09.009
Koutros, S., Silverman, D. T., Alavanja, M. C. R., Andreotti, G., Lerro, C. C., Heltshe, S., Lynch, C. F., Sandler, D. P., Blair, A., & Beane Freeman, L. E. (2016). Occupational Exposure to Pesticides and Bladder Cancer Risk. International Journal of Epidemiology, 45(3), 792–805. https://doi.org/https://doi.org/10.1093/ije/dyv195
Kumar, A., Margekar, S. L., Margekar, P., & Margekar, V. (2018). Recent advances in management of organophosphate & carbamate poisoning. Indian Journal of Medical Specialities, 9(3), 154–159. https://doi.org/https://doi.org/10.1016/j.injms.2018.06.007
Maksuk, M. (2019a). Assessment of Occupational Health Risk on The Use of Pesticides With The (HIRAC) Method in Oil Palm Plantations South Sumatera Indonesia. Health Information: Jurnal Penelitian, 11(2), 108–117. https://doi.org/https://doi.org/10.36990/hijp.v11i2.127
Maksuk, M.-. (2019b). Paraquat Concentration in Urin Workers Due to Paraquat Exposure in Palm Oil Plantation. Media Kesehatan Masyarakat Indonesia, 15(1), 63–72. https://doi.org/10.30597/mkmi.v15i1.5910
Maksuk, M., Malaka, T., Suheryanto, S., & Umayah, A. (2018). Risk Quotient of Airborne Paraquat Exposure among Workers in Palm Oil Plantation. International Journal of Public Health Science (IJPHS), 7(2), 97. https://doi.org/https://doi.org/10.11591/ijphs.v7i2.11776
Maksuk, Shobur, S., & Suzanna, S. (2021). Health Risk Due to Carbamate Exposure in Communities Around Paddy Field Areas. Jurnal Kesehatan Lingkungan (Journal of Environmental Health), 13(4), 204–210. https://doi.org/http://dx.doi.org/10.20473/jkl.v13i4.2021.204-210
Marisa, M., & Pratuna, N. D. (2018). Analysis of Cholinesterase Levels in Blood and Health Complaints in Potato Farmers at Kilometer XI in Sungai Lilin City. Jurnal Kesehatan Perintis (Perintis's Health Journal), 5(1), 122–128.
Matthews, G. (2015). Pesticides: health, safety and the environment. John Wiley & Sons.
Mrema, E. J., Ngowi, A. V., Kishinhi, S. S., & Mamuya, S. H. (2017). Pesticide exposure and health problems among female horticulture workers in Tanzania. Environmental Health Insights, 11, 1178630217715237.
Mulyana, M., Sugiarta, I., Fuk, L. J., Pratami, V. N., Fitriani, D. Y., Adi, N. P., & Soemarko, D. S. (2020). Biomonitoring of Acetylcholinesterase (AChE) Inhibitor and the Association with Hypertension among Farmers in Bandung, Indonesia. The Indonesian Biomedical Journal, 12(4), 325–332.
Mwabulambo, S. G., Mrema, E. J., Ngowi, A. V., & Mamuya, S. (2018). Health Symptoms Associated With Pesticides Exposure Among Flower And Onion Pesticide Applicators In Arusha Region. Annals of Global Health, 84(3), 369.
Negatu, B., Dugassa, S., & Mekonnen, Y. (2021). Environmental and health risks of pesticide use in Ethiopia. Journal of Health Pollution, 11(30), 210601.
Neupane, D., Jí¸rs, E., & Brandt, L. P. A. (2017). Plasma Cholinesterase Levels of Nepalese Farmers Following Exposure to Organophosphate Pesticides. Environmental Health Insights, 11, 1178630217719269. https://doi.org/https://doi.org/10.1177/1178630217719269
Nganchamung, T., Robson, M. G., & Siriwong, W. (2017). Association between Blood Cholinesterase Activity, Organophosphate Pesticide Residues on Hands, and Health Effects among Chili Farmers in Ubon Ratchathani Province, northeastern Thailand. Roczniki Państwowego Zakładu Higieny, 68(2).
Oktaviani, R., & Pawenang, E. T. (2020). Risk of Pesticide Poisoning Symptoms in Greenhouse Farmers. HIGEIA (Journal of Public Health Research and Development), 4(2), 178–188. https://doi.org/https://doi.org/10.15294/higeia.v4i2.33544
Pluth, T. B., Zanini, L. A. G., & Battisti, I. D. E. (2019). Pesticide Exposure and Cancer: an Integrative Literature Review. Saúde Em Debate, 43, 906–924. https://doi.org/https://doi.org/10.1590/0103-1104201912220
Prasanti, P., & Harningsih, T. (2022). The Correlation of Cholinesterase Enzyme Activities Based on Age in Male Farmers. Indonesian Journal of Global Health Research, 4(2), 303–308. https://doi.org/https://doi.org/10.37287/ijghr.v4i2.1042
Prihartono, N. A., Fitria, L., Ramdhan, D. H., Fitriyani, F., Fauzia, S., & Woskie, S. (2022). Determinants of Hypertension amongst Rice Farmers in West Java, Indonesia. International Journal of Environmental Research and Public Health, 19(3), 1152. https://doi.org/https://doi.org/10.3390/ijerph19031152
Rao, G. V, & Jyothsna, M. (2016). Serum Cholinesterase Levels In Organophosphorous Poisoning Patients On Ventilatory Support. Indian Journal of Clinical Anaesthesia, 3(1), 52–55. https://doi.org/https://doi.org/10.3390/ijerph14060570
Rathish, D., Senavirathna, I., Jayasumana, C., & Agampodi, S. (2018). Red Blood Cell Acetylcholinesterase Activity Among Healthy Dwellers Of An Agrarian Region In Sri Lanka: A Descriptive Cross-Sectional Study. Environmental Health and Preventive Medicine, 23(1), 1–6. https://doi.org/https://doi.org/10.1186/s12199-018-0717-0
Rosanti, E., Rahma, R. A. A., & Hamawi, M. (2021). Acetylcholinesterase Levels In Farmers Exposed To Pesticides: The Prevalence And Associated Factor. Annals of Tropical Medicine and Public Health, 24. https://doi.org/http://repo.unida.gontor.ac.id/1028/
Rudzi, S. K., Ho, Y. Bin, Tan, E. S. S., Jalaludin, J., & Ismail, P. (2022). Exposure to Airborne Pesticides and Its Residue in Blood Serum of Paddy Farmers in Malaysia. International Journal of Environmental Research and Public Health, 19(11), 6806.
Sabarwal, A., Kumar, K., & Singh, R. P. (2018). Hazardous Effects of Chemical Pesticides on Human Health–Cancer and Other Associated Disorders. Environmental Toxicology and Pharmacology, 63, 103–114. https://doi.org/https://doi.org/10.1016/j.etap.2018.08.018
Salazar-Flores, J., Pacheco-Moisés, F. P., Ortiz, G. G., Torres-Jasso, J. H., Romero-Rentería, O., Briones-Torres, A. L., & Torres-Sánchez, E. D. (2020). Occupational Exposure to Organophosphorus and Carbamates in Farmers in La Cienega, Jalisco, Mexico: Oxidative Stress and Membrane Fluidity Markers. Journal of Occupational Medicine and Toxicology, 15(1), 32. https://doi.org/10.1186/s12995-020-00283-y
Salikunna, N. A., Kurniawan, A., Fitriana, Y., & Ramadhan, M. Z. (2022). The Relationship Between Pesticide Exposure and Hypertension Incidence on Paddy Farmers in Dolago Padang Village, Central Sulawesi. IOP Conference Series: Earth and Environmental Science, 1075(1), 012015. https://doi.org/https://doi.org/10.1088/1755-1315/1075/1/012015
Santaweesuk, S., Boonyakawee, P., & Siriwong, W. (2020). Knowledge, attitude and practice of pesticide use and serum cholinesterase levels among rice farmers in Nakhon Nayok Province, Thailand. Journal of Health Research, 34(5), 379–387. https://doi.org/10.1108/JHR-09-2019-0204
Sharifzadeh, M. S., Abdollahzadeh, G., Damalas, C. A., Rezaei, R., & Ahmadyousefi, M. (2019). Determinants of Pesticide Safety Behavior Among Iranian Rice Farmers. Science of The Total Environment, 651, 2953–2960. https://doi.org/https://doi.org/10.1016/j.scitotenv.2018.10.179
Silva-Barni, M. F., Gonzalez, M., & Miglioranza, K. S. B. (2019). Comparison of the Epiphyte Tillandsia Bergeri and the XAD-Resin Based Passive Air Sampler for Monitoring Airborne Pesticides. Atmospheric Pollution Research, 10(5), 1507–1513. https://doi.org/https://doi.org/10.1016/j.apr.2019.04.008
Sine, H., Grafel, K. El, Alkhammal, S., Achbani, A., & Filali, K. (2019). Serum Cholinesterase Biomarker Study in Farmers – Souss Massa Region-, Morocco: Case–Control Ctudy. Biomarkers, 24(8), 771–775. https://doi.org/https://doi.org/10.1080/1354750X.2019.1684564
Thetkathuek, A., Yenjai, P., Jaidee, W., Jaidee, P., & Sriprapat, P. (2017). Pesticide Exposure and Cholinesterase Levels in Migrant Farm Workers in Thailand. Journal of Agromedicine, 22(2), 118–130. https://doi.org/https://doi.org/10.1080/1059924X.2017.1283276
Tutu, C. G., Manapiring, A. E., & Umboh, A. (2020). Factors Associated with Blood Cholinesterase Enzyme Activity in Pesticide Spraying Farmers. Indonesian Journal of Public Health and Community Medicine, 1(4), 40–53. https://doi.org/https://doi.org/10.35801/ijphcm.1.4.2020.31545
Upadhayay, J., Rana, M., Juyal, V., Bisht, S. S., & Joshi, R. (2020). Impact of Pesticide Exposure and Associated Health Effects. Pesticides in Crop Production: Physiological and Biochemical Action, 69–88. https://doi.org/https://doi.org/10.1002/9781119432241.ch5
Vikkey, H. A., Fidel, D., Pazou Elisabeth, Y., Hilaire, H., Hervé, L., Badirou, A., Alain, K., Parfait, H., Fabien, G., & Benjamin, F. (2017). Risk Factors Of Pesticide Poisoning and Pesticide Users' Cholinesterase Levels In Cotton Production Areas: Glazoué And Savè Townships, in Central Republic of Benin. Environmental Health Insights, 11, 1178630217704659. https://doi.org/https://doi.org/10.1177/1178630217704659
WHO, W. H. O. (2019). WHO Recommended Classification of Pesticides by Hazard and Guidelines to Classification 2009. World Health Organization.
Yadav, H., Sankhla, M. S., & Kumar, R. (2019). Pesticides-Induced Carcinogenic & Neurotoxic effect on human. Forensic Res Criminol Int J, 7(5), 243–245. https://doi.org/https://doi.org/10.15406/frcij.2019.07.00288
Yadav, I. C., & Devi, N. L. (2017). Pesticides Classification and Its Impact on Human and Environment. Environmental Science and Engineering, 6, 140–158. https://doi.org/https://doi.org/10.20546/ijcmas.2019.803.224
Zhou, J., Mainelis, G., & Weisel, C. P. (2019). Pyrethroid Levels in Toddlers' Breathing Zone Following a Simulated Indoor Pesticide Spray. Journal of Exposure Science & Environmental Epidemiology, 29(3), 389–396. https://doi.org/https://doi.org/10.1038/s41370-018-0065-6
Zulfania, K. D., Setiani, O., & Dangiran, H. L. (2017). The Relationship between Pesticide Exposure History and Blood Pressure in Spraying Farmers in Sumberejo Village, Ngablak District, Magelang Regency. Jurnal Kesehatan Masyarakat (Undip); Vol 5, No 3 (2017): MEI, 5(3), 392–401. https://doi.org/https://doi.org/10.14710/jkm.v5i3.17254
Copyright (c) 2024 The Indonesian Journal of Public Health
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
- The authors agree to transfer the transfer copyright of the article to The Indonesian Journal of Public Health effective if and when the paper is accepted for publication.
- Authors and other parties are bound to the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License for the published articles, legal formal aspect of journal publication accessibility refers to Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (CC BY-NC-SA), implies that:
- Attribution ” You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- NonCommercial ” You may not use the material for commercial purposes.
- ShareAlike ” If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.