ASSESSMENT OF RISK FACTORS ASSOCIATED WITH ACUTE RESPIRATORY INFECTIONS (ARIS) AMONG CHILDREN UNDER 5 YEARS OF AGE, PAKISTAN
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Introduction: Acute respiratory infections account for approximately 6% of the total global burden of disease; almost double the proportion compared with the other communicable diseases. Aims: To investigate the link between risk factors & ARIs in Pakistani pediatric population under 5 with different socio-demographic profiles. Methods: Research was conducted as a cross-sectional study, utilizing the Pakistan DHS 2017-18 data, after ethical approval for the utilization of the dataset. Study variables were defined as age and gender of the child, place of residence, maternal education, wealth index, breastfeeding, and the immunization status of the child. Sample size (n = 39,799) was determined as per the inclusion and exclusion criteria. Prevalence of ARIs was estimated and the association between ARIs and socio-demographic factor and child’s immunization was examined. Results: Out of 39,799 children, 51.6% were males, 21.0 % were aged 36 – 47 months, 73.7% were the rural residents, 23% belonged to lowest wealth index quintiles. The mothers of 43.7% children were illiterate and 55.7% of the children were breastfed. ARIs proportion among the sample was 14.3%. Significant association was observed between ARIs and age (p=0.000), gender of the child (p=0.001), residence (p=0.000), economic deprivation (p=0.000), maternal education (p=0.000) and breastfeeding (p=0.000), vitamin A administration (p=0.021), BCG (p=0.008), pentavalent (p=0.008), measles (p=0.000), and pneumococcal vaccination (p=0.020). Conclusion: Socio-demographic characteristics, i.e., age and gender of the child, accommodation, economic deprivation, maternal education, breast-feeding and poor vaccination uptake were observed to be positively correlated with ARIs among children under 5 years of age in Pakistan.
Adesanya, O., Chiao, C., 2017. Environmental Risks Associated with Symptoms of Acute Respiratory Infection among Preschool Children in North-Western and South-Southern Nigeria Communities. Int. J. Environ. Res. Public. Health 14, 1396. https://doi.org/10.3390/ijerph14111396
Arpitha, G., Rehman, M.A., Ashwitha, G, 2014. Effect of severity of malnutrition on pneumonia in children aged 2 M-5Y at a tertiary care center in Khammam, Andhra Pradesh: a clinical study. https://doi.org/10.36347/sjams.2014.v02i06.069
Astale, T., Chenault, M., 2015. Help-Seeking Behavior for Children with Acute Respiratory Infection in Ethiopia: Results from 2011 Ethiopia Demographic and Health Survey. PLoS ONE 10, e0142553. https://doi.org/10.1371/journal.pone.0142553
Bawankule, R., Singh, A., Kumar, K., Shetye, S., 2017. Does Measles Vaccination Reduce the Risk of Acute Respiratory Infection (ARI) and Diarrhea in Children: A Multi-Country Study? PLoS ONE 12, e0169713. https://doi.org/10.1371/journal.pone.0169713
Caballero, M.T., Bianchi, A.M., Nuño, A., Ferretti, A.J.P., Polack, L.M., Remondino, I., Rodriguez, M.G., Orizzonte, L., Vallone, F., Bergel, E., Polack, F.P., 2019. Mortality Associated With Acute Respiratory Infections Among Children at Home. J. Infect. Dis. 219, 358–364. https://doi.org/10.1093/infdis/jiy517
Doan, Q., Enarson, P., Kissoon, N., Klassen, T.P., Johnson, D.W., 2014. Rapid viral diagnosis for acute febrile respiratory illness in children in the Emergency Department. Cochrane Database Syst. Rev. https://doi.org/10.1002/14651858.CD006452.pub4
Fathima, P., Blyth, C.C., Lehmann, D., Lim, F.J., Abdalla, T., De Klerk, N., Moore, H.C., 2018. The Impact of Pneumococcal Vaccination on Bacterial and Viral Pneumonia in Western Australian Children: Record Linkage Cohort Study of 469589 Births, 1996–2012. Clin. Infect. Dis. 66, 1075–1085. https://doi.org/10.1093/cid/cix923
Gebrerufael, G.G., Hagos, B.T., 2023. Prevalence and predictors of acute respiratory infection among children under-five years in Tigray regional state, northern Ethiopia: a cross sectional study. BMC Infect. Dis. 23, 743. https://doi.org/10.1186/s12879-023-08701-2
Harerimana, J.-M., Nyirazinyoye, L., Thomson, D.R., Ntaganira, J., 2016. Social, economic and environmental risk factors for acute lower respiratory infections among children under five years of age in Rwanda. Arch. Public Health 74, 19. https://doi.org/10.1186/s13690-016-0132-1
Hollm-Delgado, M.-G., Stuart, E.A., Black, R.E., 2014. Acute Lower Respiratory Infection Among Bacille Calmette-Guérin (BCG)–Vaccinated Children. Pediatrics 133, e73–e81. https://doi.org/10.1542/peds.2013-2218
Imdad, A., Mayo-Wilson, E., Haykal, M.R., Regan, A., Sidhu, J., Smith, A., Bhutta, Z.A., 2022. Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age. Cochrane Database Syst. Rev. 2022. https://doi.org/10.1002/14651858.CD008524.pub4
Imran, M.I.K., Inshafi, M.U.A., Sheikh, R., Chowdhury, M.A.B., Uddin, M.J., 2019. Risk factors for acute respiratory infection in children younger than five years in Bangladesh. Public Health 173, 112–119. https://doi.org/10.1016/j.puhe.2019.05.011
Jackson, S., Mathews, K.H., Pulanić, D., Falconer, R., Rudan, I., Campbell, H., Nair, H., 2013. Risk factors for severe acute lower respiratory infections in children – a systematic review and meta-analysis. Croat. Med. J. 54, 110–121. https://doi.org/10.3325/cmj.2013.54.110
Kamal, M.M., Hasan, M.M., Davey, R., 2015. Determinants of childhood morbidity in Bangladesh: evidence from the Demographic and Health Survey 2011. BMJ Open 5, e007538. https://doi.org/10.1136/bmjopen-2014-007538
Kaware, A.C., Kamble, N.H., Mangulikar, S.K., 2017. Study of risk factors of acute respiratory infections in children admitted in a tertiary care hospital of Southern Maharashtra. Int. J. Community Med. Public Health 4, 3129. https://doi.org/10.18203/2394-6040.ijcmph20173692
Lamberti, L.M., Zakarija-Grković, I., Fischer Walker, C.L., Theodoratou, E., Nair, H., Campbell, H., Black, R.E., 2013. Breastfeeding for reducing the risk of pneumonia morbidity and mortality in children under two: a systematic literature review and meta-analysis. BMC Public Health 13, S18. https://doi.org/10.1186/1471-2458-13-S3-S18
Liu, W.K., Liu, Q., Chen, D.H., Liang, H.X., Chen, X.K., Chen, M.X., Qiu, S.Y., Yang, Z.Y., Zhou, R., 2014. Epidemiology of Acute Respiratory Infections in Children in Guangzhou: A Three-Year Study. PLoS ONE 9, e96674. https://doi.org/10.1371/journal.pone.0096674
Mameli, C., Picca, M., Buzzetti, R., Pace, M.E., Badolato, R., Cravidi, C., Zuccotti, G.V., Marchisio, P., for the Italian Society of Paediatrics Lombardy Section, Sala, M., Di Cosimo, M.E., 2022. Incidence of acute respiratory infections in preschool children in an outpatient setting before and during Covid-19 pandemic in Lombardy Region, Italy. Ital. J. Pediatr. 48, 18. https://doi.org/10.1186/s13052-022-01221-w
Merera, A.M., 2021. Determinants of acute respiratory infection among under-five children in rural Ethiopia. BMC Infect. Dis. 21, 1203. https://doi.org/10.1186/s12879-021-06864-4
Meskill, S.D., O’Bryant, S.C., 2020. Respiratory Virus Co-infection in Acute Respiratory Infections in Children. Curr. Infect. Dis. Rep. 22, 3. https://doi.org/10.1007/s11908-020-0711-8
Musa, N., Gul, R., Mehmood, Y., Afridi, S., 2016. Frequency of Risk Factors Leading to Acute Respiratory Infections Among Children Under Two Year’s Age and their Gender and Age Wise Comparison. J. Gandhara Med. Dent. Sci. 3, 16–21. https://doi.org/10.37762/jgmds.3-01.43
Nguipdop-Djomo, P., Heldal, E., Rodrigues, L.C., Abubakar, I., Mangtani, P., 2016. Duration of BCG protection against tuberculosis and change in effectiveness with time since vaccination in Norway: a retrospective population-based cohort study. Lancet Infect. Dis. 16, 219–226. https://doi.org/10.1016/S1473-3099(15)00400-4
Nirmolia, N., Mahanta, T.G., Boruah, M., Rasaily, R., Kotoky, R.P., Bora, R., 2018. Prevalence and risk factors of pneumonia in under five children living in slums of Dibrugarh town. Clin. Epidemiol. Glob. Health 6, 1–4. https://doi.org/10.1016/j.cegh.2017.07.004
Rahmadiena, Q., Risanti, E.D., Dewi, L.M., Setiawati, S.R., 2021. Low birth weight and immunizations status: risk factors of acute respiratory infection in children 2-5 years. Epidemiol. Soc. Health Rev. ESHR 3, 8–14. https://doi.org/10.26555/eshr.v3i1.2295
Ramani, V.K., 2016. Acute Respiratory Infections among Under- Five Age Group Children at Urban Slums of Gulbarga City: A Longitudinal Study. J. Clin. Diagn. Res. https://doi.org/10.7860/JCDR/2016/15509.7779
Savitha, A., Gopalakrishnan, S., 2018. Determinants of acute respiratory infections among under five children in a rural area of Tamil Nadu, India. J. Fam. Med. Prim. Care 7, 1268. https://doi.org/10.4103/jfmpc.jfmpc_131_18
Seidu, A.-A., Dickson, K.S., Ahinkorah, B.O., Amu, H., Darteh, E.K.M., Kumi-Kyereme, A., 2019. Prevalence and determinants of Acute Lower Respiratory Infections among children under-five years in sub–Saharan Africa: Evidence from demographic and health surveys. SSM - Popul. Health 8, 100443. https://doi.org/10.1016/j.ssmph.2019.100443
Sharma, D., Kuppusamy, K., Bhoorasamy, A., 2013. Prevalence of acute respiratory infections (ari) and their determinants in under five children in urban and rural areas of Kancheepuram district, South India. Ann. Trop. Med. Public Health 6.
Shi, T., McAllister, D.A., O’Brien, K.L., Simoes, E.A.F., Madhi, S.A., Gessner, B.D., Polack, F.P., Balsells, E., Acacio, S., Aguayo, C., Alassani, I., Ali, A., Antonio, M., Awasthi, S., Awori, J.O., Azziz-Baumgartner, E., Baggett, H.C., Baillie, V.L., Balmaseda, A., Barahona, A., Basnet, S., Bassat, Q., Basualdo, W., Bigogo, G., Bont, L., Breiman, R.F., Brooks, W.A., Broor, S., Bruce, N., Bruden, D., Buchy, P., Campbell, S., Carosone-Link, P., Chadha, M., Chipeta, J., Chou, M., Clara, W., Cohen, C., De Cuellar, E., Dang, D.-A., Dash-yandag, B., Deloria-Knoll, M., Dherani, M., Eap, T., Ebruke, B.E., Echavarria, M., De Freitas Lázaro Emediato, C.C., Fasce, R.A., Feikin, D.R., Feng, L., Gentile, A., Gordon, A., Goswami, D., Goyet, S., Groome, M., Halasa, N., Hirve, S., Homaira, N., Howie, S.R.C., Jara, J., Jroundi, I., Kartasasmita, C.B., Khuri-Bulos, N., Kotloff, K.L., Krishnan, A., Libster, R., Lopez, O., Lucero, M.G., Lucion, F., Lupisan, S.P., Marcone, D.N., McCracken, J.P., Mejia, M., Moisi, J.C., Montgomery, J.M., Moore, D.P., Moraleda, C., Moyes, J., Munywoki, P., Mutyara, K., Nicol, M.P., Nokes, D.J., Nymadawa, P., Da Costa Oliveira, M.T., Oshitani, H., Pandey, N., Paranhos-Baccalà, G., Phillips, L.N., Picot, V.S., Rahman, M., Rakoto-Andrianarivelo, M., Rasmussen, Z.A., Rath, B.A., Robinson, A., Romero, C., Russomando, G., Salimi, V., Sawatwong, P., Scheltema, N., Schweiger, B., Scott, J.A.G., Seidenberg, P., Shen, K., Singleton, R., Sotomayor, V., Strand, T.A., Sutanto, A., Sylla, M., Tapia, M.D., Thamthitiwat, S., Thomas, E.D., Tokarz, R., Turner, C., Venter, M., Waicharoen, S., Wang, J., Watthanaworawit, W., Yoshida, L.-M., Yu, H., Zar, H.J., Campbell, H., Nair, H., 2017. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study. The Lancet 390, 946–958. https://doi.org/10.1016/S0140-6736(17)30938-8
Solomon, O., Odu, O., Amu, E., Solomon, O., Bamidele, J., Emmanuel, E., Parakoyi, B., 2018. Prevalence and risk factors of acute respiratory infection among under fives in rural communities of Ekiti State, Nigeria. Glob. J. Med. Public Health 7, 12.
Sonego, M., Pellegrin, M.C., Becker, G., Lazzerini, M., 2015. Risk Factors for Mortality from Acute Lower Respiratory Infections (ALRI) in Children under Five Years of Age in Low and Middle-Income Countries: A Systematic Review and Meta-Analysis of Observational Studies. PLoS ONE 10, e0116380. https://doi.org/10.1371/journal.pone.0116380
Sultana, M., Sarker, A.R., Sheikh, N., Akram, R., Ali, N., Mahumud, R.A., Alam, N.H., 2019. Prevalence, determinants and health care-seeking behavior of childhood acute respiratory tract infections in Bangladesh. PLoS ONE 14, e0210433. https://doi.org/10.1371/journal.pone.0210433
Tazinya, A.A., Halle-Ekane, G.E., Mbuagbaw, L.T., Abanda, M., Atashili, J., Obama, M.T., 2018. Risk factors for acute respiratory infections in children under five years attending the Bamenda Regional Hospital in Cameroon. BMC Pulm. Med. 18, 7. https://doi.org/10.1186/s12890-018-0579-7
Ullah, M.B., Mridha, M.K., Arnold, C.D., Matias, S.L., Khan, M.S.A., Siddiqui, Z., Hossain, M., Paul, R.R., Dewey, K.G., 2019. Factors associated with diarrhea and acute respiratory infection in children under two years of age in rural Bangladesh. BMC Pediatr. 19, 386. https://doi.org/10.1186/s12887-019-1738-6
Yaya, S., Bishwajit, G., 2019. Burden of Acute Respiratory Infections Among Under-Five Children in Relation to Household Wealth and Socioeconomic Status in Bangladesh. Trop. Med. Infect. Dis. 4, 36. https://doi.org/10.3390/tropicalmed4010036
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