ANALYSIS FACTORS AFFECTING OPPORTUNISTIC INFECTIONS IN WOMEN HIV IN DR SOETOMO HOSPITAL

Opportunistic Infections HIV/AIDS Women ARVs CD4 levels Viral Load Levels

Authors

June 10, 2025

Background: Human Immunodeficiency Virus (HIV) is a significant global health concern. In Indonesia, women account for 35,1% of HIV cases. In East Java, 1.062 new cases were recorded from January to March 2023, with the highest number of cases in Surabaya, with a total 663 cases. Opportunistic Infections affect to HIV patients with weakened immune systems. In Indonesia, tuberculosis is the most prevalent opportunistic infection among HIV patients, representing 62,1% of cases. Tuberculosis is commonly found in women with HIV, putting them at risk of transmitting the infection to their unborn child. This research is to analyze  the factors that influence the emergence of opportunistic infections in women with HIV.    Methods: The type of research used in this study is quantitative with an observational research design. The samples taken are the entire population that meets the inclusion and exclusion criteria. The number of samples used is 94 female with HIV. Results: The results of the study showed that the duration of infection did not have a significant effect on opportunistic infections (p = 0,402), while the level of adherence to ARV consumption (p = 0,003), CD4 levels (p = <0,001), and viral load levels (p = 0,001) significantly increased the risk of opportunistic infections. Conclusion: There is a significant influence on the level of adherence to ARV consumption, CD4 levels and viral load levels on the emergence of opportunistic infections in female patients with HIV at Dr. Soetomo Hospital.