Formulation And Physical Evaluation of Body Scrub Cream From 95% Ethanol Extract of Breadfruit Peel (Artocarpus altilis) as Antioxidants
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Background: Breadfruit (Artocarpus altilis) peel contains many chemical compounds including alkaloids, flavonoids, saponins, polyphenols, and steroids/terpenoids. Breadfruit peel has potential as an antioxidant because it contains phenolic compounds, especially flavonoids and polyphenols. Objective: The aim of this study was to formulate and physically evaluate the preparation of a scrub cream from a 95% ethanol extract of breadfruit peel (Artocarpus altilis) and test its antioxidant activity. Methods: Body scrub cream formulations were prepared using different extract concentrations, such as F1 (no extract), F2 1%, F3 3%, F4 5%, and F5 (Vit C as an equalizer for the antioxidant activity test). Body scrub cream was formulated as an oil-in-water type cream preparation using breadfruit starch as a scrub. Physical evaluation of this preparation consisted of organoleptic, homogeneity, viscosity, pH, spreadability, adhesiveness, and room-temperature storage tests. The antioxidant activity was evaluated using the DPPH method. Results: The results of the physical evaluation test showed that the body scrub cream produced good results and complied with the requirements of cream products. Antioxidant activity test results show the IC50 value of each formula is F1 (without extract) 107.8 µg/mL, F2 (1%) 72.48 µg/mL, F3 (3%) 56.54 µg/mL, F4 (5%) 43.40 µg/mL and F5 (vitamin C K+) 38.94 µg/mL. Conclusion: Based on these observations, the best formula is Formula 3 because the antioxidant test results are classified as strong, and the physical evaluation tests are considered stable.
Agata, W.L. and Sulandjari, S. (2017) ‘Pengaruh Penambahan Tepung Kulit Pisang Kepok dan Kulit Jeruk Nipis Terhadap Hasil Lulur Tradisional’, e-journal, 06(01), pp. 73–80.
Aljanah, F.W., Oktavia, S. and Noviyanto, F. (2022) ‘Formulasi dan Evaluasi Sediaan Hand Body Lotion Ekstrak Etanol Daun Semangka (Citrullus lanatus) sebagai Antioksidan’, Formosa Journal of Applied Sciences, 1(5), pp. 799–818. Available at: https://doi.org/10.55927/fjas.v1i5.1483.
Aprilliani, A., Suganda, A.G. and Hartati, R. (2018) ‘Uji Inhibisi Aktivitas Enzim Tirosinase Beberapa Jenis Tumbuhan Zingiberaceae’, Jurnal Ilmiah Farmasi, 14(1), pp. 46–58. Available at: http://journal.uii.ac.id/index.php/JIF46.
Azkianti, E. and Lestari, U. (2022) ‘Uji Sifat Fisikokimia Sediaan Body Scrub Fraksionat Ekstrak Diklorometan Kulit Buah Sukun (Artocarpus altilis)’, Jurnal Ilmu Farmasi dan Farmasi Klinik (JIFFK), 19(2), pp. 63–71. Available at: www.unwahas.ac.id/publikasiilmiah/index.php/ilmufarmasidanfarmasiklinik.
Binuni, R., M.W.H.S.Y. (2020) ‘Uji Aktivitas Antioksidan Ekstrak Daun Mangrove Sonneratia alba Dari Kecamatan Tagulandang, Sulawesi Utara Menggunakan Metode DPPH’, Jurnal Biofarmasetikal Tropis, 3(1), pp. 79–85.
Ghozali, I. (2018) Aplikasi Analisis Multivariate dengan Program IBM SPSS. 25. 9th edn. Semarang: Universitas Diponegoro.
Hilda, D., Arini, A. and Nancy, C.D. (2021) ‘Formulation of Body Scrub Cream from Extract of Arabica Green Coffee (Coffea arabica L.) as Antioxidant’, Atlantis Press, 33, pp. 337–342. Available at: https://doi.org/https://doi.org/10.2991/ahsr.k.210115.071.
Kurniawati, F.I. and Sutoyo, S. (2021) ‘Review Artikel: Potensi Bunga Tanaman Sukun (Artocarpus altilis [Park. I] Fosberg) Sebagai Bahan Antioksidan Alami’, UNESA Journal of Chemistry, 10(1), pp. 1–11.
Lestari, U., Farid, F. and Sari, M. (2017) ‘Formulasi dan Uji Sifat Fisik Lulur Body Scrub Arang Aktif dari Cangkang Sawit ( Elaeis Guineensis Jacg) sebagai Detoksifikasi’, Jurnal Sains dan Teknologi Farmasi, 19(1), pp. 74–79.
Malik, F., Ihsan, S., Meilany, E. and Hamsidi, R. (2020) ‘Formulation of Body Scrub from Ethanol Extract of Cassava Leaves (Manihot esculenta) As Antioxidant’, Journal of Vocational Health Studies, 4(1), pp. 21–28. Available at: https://doi.org/10.20473/jvhs.V4I1.2020.21-28.
Masaki, H. (2010) ‘Role of Antioxidants In The Skin: Anti-aging Effects’, Journal of Dermatological Science, 58(2), pp. 85–90. Available at: https://doi.org/10.1016/j.jdermsci.2010.03.003.
Molyneux, P. (2004) ‘The Use Of The Stable Free Radical diphenylpicryl-hydrazyl (DPPH) For Estimating Antioxidant Activity’, Songklanakarin J.Sci. Technol, 26(2), pp. 211–219.
Musdalipah, Haisumanti and Reymon (2016) ‘Formulasi Body Scrub Sari Ubi Jalar Ungu (Ipomoea Batatas L.) Varietas Ayamurasaki’, Warta Farmasi, 5(1), pp. 1–12.
Putra, M.M., Dewantara, I.G.N.A. and Swastini, D.A. (2014) ‘Pengaruh Lama Penyimpanan Terhadap Nilai pH Sediaan Cold Cream Kombinasi Ekstrak Kulit Buah Manggis (Garcinia mangostana L.) Herba Pegagan (Centella asiatica) dan Daun Gaharu (Gyrinops versteegii (gilg) Domke)’, Jurnal Farmasi Udayana, 3(1), pp. 18–21.
SNI (1996) ‘SNI 16-4399-1996 Sediaan Tabir Surya’. Jakarta.
Wibowo, A.N., Suwendar, D., Fitrianingsih, S.P., Farmasi, P., Matematika, F., Ilmu, D. and Alam, P. (2017) ‘Evaluasi Potensi Aktivitas Antioksidan Alami dan Aktivitas Sitotoksik Ekstrak Etanol Kulit Buah Sukun (Artocarpus altilis (Parkinson) Fosberg) Secara In Vitro’, Prosiding Farmasi , 3(1), pp. 6–13.
Yusuf, A.L., Nurawaliah, E. and Harun, N. (2017) ‘Uji Efektivitas Gel Ekstrak Etanol Daun Kelor (Moringa oleifera L.) Sebagai Antijamur Malassezia furfur, Kartika : Jurnal Ilmiah Farmasi, 5(2), p. 62. Available at: https://doi.org/10.26874/kjif.v5i2.119.
Zaky, M., Rusdiana, N. and Darmawati, A. (2021) ‘Formulasi Dan Evaluasi Fisik Sediaan Gel Antioksidan Ekstrak Etanol 70% Daun Belimbing Wuluh (Averrhoa bilimbi L.) Menggunakan Metode DPPH’, Jurnal Farmagazine, 8(2), pp. 26–36. Available at: https://doi.org/10.47653/farm.v8i2.556.
Zuhra, C.F., Ginting, M., Marpongahtun and Syufiatun, A. (2016) ‘Modifikasi Pati Sukun Dengan Metode Ikat Silang Menggunakan Trinatrium Trimetafosfat’, Chimica et Natura Acta , 4(3), pp. 142–146.
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