Assessment of Geriatrics Patients with Cardiovascular Disease Prescriptions for Appropriateness of Medications by Using Beers Criteria in Muhammadiyah Lamongan Hospital
Downloads
Background: The number of geriatric residents has increased annually. Owing to pathological and physiological conditions, the geriatric population tends to consume more medications, thereby increasing their risk of adverse side effects and drug interactions. Objective: The objective of this study was to evaluate the appropriateness of therapy for outpatient geriatric patients with cardiovascular disease at Muhammadiyah Lamongan Hospital from August to October 2023. Methods: The American Geriatrics Society (AGS) Beers Criteria are one of the tools used to identify drugs whose potential harm outweighs the expected benefits and should be avoided in the elderly population. This study employed a descriptive method, with retrospective data collection from secondary sources, including medical records and electronic prescriptions. Results: The findings revealed that out of 252 prescriptions for geriatric patients with cardiovascular disease, four types of medications were potentially inappropriate according to the Beers Criteria: nifedipine with 23 prescriptions (9.13%), amiodarone with one prescription (0.40%), digoxin with 13 prescriptions (5.16%), and diltiazem with four prescriptions (1.59%). Conversely, three types of medications were deemed appropriate: aspirin (96 prescriptions, 38.10%), digoxin (30 prescriptions, 11.90%), and diltiazem (11 prescriptions, 4.37%). In conclusion, of the 252 prescriptions reviewed for geriatric patients with cardiovascular disease, three types of drugs are appropriate, while four types increase the risk of potentially inappropriate treatment (PIM) based on the Beers Criteria. Conclusion: These findings underscore the need for careful consideration to mitigate the risk of drug reactions. If the medication cannot be used in geriatric patients, an alternative therapy should be used or a dose adjustment may be necessary.
Amisi, W. G., Nelwan, J. E. & Kolibu, F. K. (2018). Hubungan antara Hipertensi dengan Kejadian Penyakit Jantung Koroner pada Pasien yang Berobat di Rumah Sakit Umum Pusat Prof. Dr. R. D. Kandou Manado, Kesmas; 7; pp. 1–7.
Arfania, M., Risna, K., Musa, K. A. E., Ardianti, R. & Safitri, Y. A. (2023). Literatur Review Efektivitas Beta Bloker Pada Terapi Pasien Gagal Jantung, 3; pp. 8076–8088.
Badan Pusat Statistik (2022). Statistik Penduduk Lanjut Usia 2022.
Badawoud, A. M., Alanizi, A., Alnakhli, A. O., Alzahrani, W., AlThiban, H. S., AlKhurayji, R. W., Alnakhli, A. M., Almoudi, J. A. & Yami, M. S. A. (2024). Appropriateness of anticoagulation level in older adult patients on Warfarin: A multicenter retrospective study, Saudi Pharmaceutical Journal; 32; p. 101906. doi: 10.1016/j.jsps.2023.101906.
Di, J., Wei Y., Zhang, G., Yue, Y. & Sun, S. (2023). Comparison of clinical effects and costs among dabigatran etexilate, rivaroxaban and warfarin in elderly patients with atrial fibrillation, American journal of translational research; 15; pp. 3639–3646.
Dinkes lamongan (2021). Dinas kesehatan Kabupaten lamongan, Profil Kesehatan Kabupaten Lamongan.
Drug.com (2024). Drug Interaction Report.
Firdaus (2016). Penggunaan Obat Anti Platelet pada Pasien Penyakit Jantung Koroner, pp. 1–3.
Handayani, U., Alifiar, I. & Idacahyati, K. (2018). Potentially inappropriate medication among geriatric inpatients Studi ketidaksesuaian pengobatan pada pasien geriatri rawat inap, Jurnal Ilmiah Farmasi; 15; pp. 87–93. doi: org/10.20885/jif.vol14.iss2.art4.
Health, Q. (2024). Guideline for Warfarin Management in the Community, (February).
HUA, Q., Fan, L., Wang, W. W. & Li, Jing. (2024). 2023 Guideline for the management of hypertension in the elderly population in China, Journal of Geriatric Cardiology; 21; pp. 589–630. doi: 10.26599/1671-5411.2024.06.001.
Julaiha, S. (2021). Faktor yang Berhubungan dengan Kejadian Potentially Inappropriate Medisation Berdasarkan Kriteria STOPP START pada Pasien Geriatri dengan Gangguan Kardiovaskuler, Jurnal Kesehatan Metro Sai Wawai; 14; pp. 156–167.
Kashif M. K. (2023). Nifedipine, National Library Of Medicine.
Mutarobin. (2018). Sistem Kardiovaskuler Acute Coronary Syndrome ( ACS ) ; pp. 1–72.
Panel, U. E. (2023). American Geriatrics Society 2023 updated AGS Beers Criteria® for potentially inappropriate medication use in older adults, Journal of the American Geriatrics Society; (March). doi: 10.1111/jgs.18372.
Puspitasari, C. E., Widiyastuti, R., Dewi, N. M. A. R., Woro, O. Q. L. & Syamsun, A. (2022). Profil Drug Related Problems (DRPs) pada Pasien Hipertensi di Instalasi Rawat Jalan Rumah Sakit Pemerintah di Kota Mataram Tahun 2018, Jurnal Sains dan Kesehatan; 4; pp. 77–87. doi: 10.25026/jsk.v4ise-1.1692.
Rampengan, S. H. (2014). Buku praktis kardiologi, Badan Penerbit Fakultas Kedokteran Universitas Indonesia.
Riskesdas (2018). Laporan Riskesdas 2018 Kementrian Kesehatan Republik Indonesia, Laporan Nasional Riskesdas 2018; pp. 154–165.
Sasfi, S. M. (2020). Pola Peresepan Pasien Lanjut Usia Poli Penyakit Dalam Rawat Jalan Di Rsud Dr. Soedarso Kota Pontianak Periode Desember 2018 – Juli 2019, Jurnal Berkala Epidemiologi; 5; pp. 90–96.
McNeil, J. J., Wolfe, R., Woods, R. L., Tonkin, A. M., Donnan, G. A., Nelson, M. R., Reid, C. M., Lockery, J. E., Kirpach, B., Storey, E., Shah, R. C., Williamson, J. D., Margolis, K. L., Ernst, M. E., Abhayaratna, W. P., Stocks, N., Fitzgerald, S. M., Orchard, S. G., Trevaks, R. E., Beilin, L. J., Johnston, C. I., Ryan, J., Radziszewska, B., Jelinek, M., Malik, M., Eaton, C. B., Brauer, D., Cloud, G., Wood, E. M., Mahady, S. E., Satterfield, S., Grimm, R., Murray, A. M. & ASPREE Investigator Group. (2018). Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly, New England Journal of Medicine; 379; pp. 1509–1518. doi: 10.1056/nejmoa1805819.
Tanton, M. M., Samii, L., Leung, G. & Pearce, P. (2020). Amiodarone-induced neuromyopathy in a geriatric patient, BMJ Case Reports; 13; pp. 1–3. doi: 10.1136/bcr-2020-236620.
Unger, T., Borghi, C., Charchar, F., Khan, N. A., Poulter, N. R., Prabhakaran, D., Ramirez, A., Schlaich, M., Stergiou, G. S., Tomaszewski, M., Wainford, R. D., Williams, B. & Schutte, A. E. (2020). Practice Guidelines 2020 International Society of Hypertension Global Hypertension Practice Guidelines International Society of Hypertension; pp. 1–24. doi: 10.1161/HypertensionAHA.120.15026.
Copyright (c) 2025 JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
1. The copyright of this journal belongs to the Editorial Board and Journal Manager with the author's knowledge, while the moral right of the publication belong to the author.
2. The formal legal aspect of journal publication accessibility refers to the Creative Commons Attribution-Non-Commercial-Share Alike (CC BY-NC-SA), which implies that the publication can be used for non-commercial purposes in its original form.
3. Every publication (print/electronic) is open access for educational, research, and library purposes. In addition to the objectives mentioned above, the editorial board is not responsible for copyright infringement
.jpg)
