Bone Tuberculosis: Clinical Profile of 40 Patients in Dr. Soetomo General Hospital Surabaya
Downloads
Introduction: Bone and joint tuberculosis are specific infection inflammation of Mycobacterium tuberculosis, mostly affected bone and joint confirmed by acceleration of vascular supply to vertebrae and growth line of long bone. The aim of this study is to know clinical profile of bone and joint tuberculosis' patients.
Methods: This study was conducted using descriptive observational method, samples were tested by observation descriptive test.
Results: The average ages of bone and joint tuberculosis hospitalized patients of RSUD Dr. Soetomo Surabaya are 35-44 years. There are 22 cases on male (55%) and 18 cases on female (45%) with 29 subjects of Hb's abnormal number (72.5%), 15 subjects of abnormal leucocytes (37.5%), 20 subjects of abnormal thrombocyte (50%), 34 subjects of abnormal ESR (94.4%), 20 patients of abnormal C-reactive protein (54.1%), 11 subjects of abnormal serum creatinine (28.9%), 13 subjects of abnormal sodium level (35.1%), 15 patients of abnormal potassium level (40.5%), and 16 patients of abnormal chloride level (43.2%). There are 16 subjects with smoking history (40%), 29 subjects of positive tuberculosis history (72.5%), 6 subjects with positive tuberculosis family history (15%), 30 subjects of pain as main problems (75%), 5 subjects of swelling or pus as main problems (12.5%), 5 subjects of extremities disability as main problems (12.5%). Dominant location of infection is vertebrae (95%) which are suffered by 38 subjects with thoracal as the main level of infection, suffered by 15 subjects (50%). Other levels of infection are lumbal with 12 subjects (40%), cervical with 3 subjects (10%), and pelvis or thigh with 2 subjects (5%).
Conclusion: From 40 subjects, bone and joint tuberculosis mostly suffered by elderly, male risks more than female. Most of hematology tests results were abnormal. Most subjects suffered abnormal C-reactive protein. Most subjects' hematology tests were BUN, creatinine serum, and electrolyte normal. Number of subjects with smoking habits was dominant. Most subjects were having tuberculosis history but negative family history. Most subjects complained about pain with vertebrae level thoracal as dominant location of infection.
Yang L and Liu Z. Analysis and Therapeutic Schedule of the Postoperative Recurrence of Bone Tuberculosis. J Orthop Surg Res. 2013; 8: 47-.
Organization WH. Global Tuberculosis Report 2018. Geneva: World Health Organization, 2018.
Sharma SK and Mohan A. Tuberculosis: From an Incurable Scourge to a Curable Disease - Journey Over a Millennium. The Indian Journal of Medical Research. 2013; 137: 455-93.
Arora K and Chaudhary P. Tuberculosis of Talus Bone in Middle Aged Man – A Case Report. International Journal of Orthopaedic and Trauma Nursing. 2014; 18: 35-8.
Agrawal V, Patgaonkar PR and Nagariya SP. Tuberculosis of Spine. J Craniovertebr Junction Spine. 2010; 1: 74-85.
Hu S, Guo J, Ji T, Shen G and Kuang A. Multifocal Osteoarticular Tuberculosis of the Extremities in an Immunocompetent Young Man without Pulmonary Disease: A Case Report. Exp Ther Med. 2015; 9: 2299-302.
Pigrau-Serrallach C and Rodríguez-Pardo D. Bone and Joint Tuberculosis. Eur Spine J. 2013; 22 Suppl 4: 556-66.
Moon M-S. Tuberculosis of Spine: Current Views in Diagnosis and Management. Asian Spine J. 2014; 8: 97-111.
Kritsaneepaiboon S, Andres MM, Tatco VR, Lim CCQ and Concepcion NDP. Extrapulmonary Involvement in Pediatric Tuberculosis. Pediatric Radiology. 2017; 47: 1249-59.
N A, Ahmad F and Huda N. Osteoarticular Tuberculosis-A Three Years' Retrospective Study. J Clin Diagn Res. 2013; 7: 2189-92.
Alghamdi AA, Awan FS, Maniyar IH and Alghamdi NA. Unusual Manifestation of Extrapulmonary Tuberculosis. Case Reports in Medicine. 2013; 2013: 353798.
Garg RK and Somvanshi DS. Spinal Tuberculosis: A Review. J Spinal Cord Med. 2011; 34: 440-54.
Karakaplan M, Köroğlu M, Ergen E, Aslantürk O, Özdemir ZM and Ertem K. Isolated Tuberculosis of Capitate and Triquetrum. J Wrist Surg. 2017; 6: 70-3.
Irawati, Melinda H and Idjradinata PS. Kesesuaian Nilai C-Reactive Protein dan Procalcitonin dalam Diagnosis Pneumonia Berat pada Anak. Sari Pediatri. 2010; 12: 78.
Harrison M. Erythrocyte Sedimentation Rate and C-Reactive Protein. Aust Prescr. 2015; 38: 93-4.
Jonaidi Jafari N, Izadi M, Sarrafzadeh F, Heidari A, Ranjbar R and Saburi A. Hyponatremia Due to Pulmonary Tuberculosis: Review of 200 Cases. Nephrourol Mon. 2013; 5: 687-91.
Inayat F, Jafar MS, Ali NS, Hussain Q and Hurairah A. Enigma of Extrapulmonary Tuberculosis: Where Do We Stand? Cureus. 2017; 9: E1554.
Prevention CFDCA. How TB Spreads: (2016).
Loddenkemper R, Lipman M and Zumla A. Clinical Aspects of Adult Tuberculosis. Cold Spring Harbor Perspectives in Medicine. 2015; 6: A017848.
Maricnda M, Cozzolino A, Attingenti P, Cozzolino F and Milano . Osteoarticular Tuberculosis in a Developed Country. The Journal of Infection. 2007; 54: 375-80.
1. The journal allows the author to hold the copyright of the article without restrictions.
2. The journal allows the author(s) to retain publishing rights without restrictions
3. The formal legal aspect of journal publication accessibility refers to Creative Commons Atribution-Share Alike 4.0 (CC BY-SA).
