The Maternal Risk Factors for Preterm Birth in Universitas Airlangga Hospital Surabaya in 2017-2018
Introduction: Preterm birth becomes a global problem due to its high rate of morbidity and mortality. In 2010, it is estimated approximately 15 premature birth cases per 100 lives birth in Indonesia. This study aimed to analyze the maternal risk factors towards preterm birth at Universitas Airlangga Hospital Surabaya in 2017-2018.
Methods: This was observational analytic study using case-control approach to observe 178 medical records at Universitas Airlangga Hospital Surabaya. The population of this study was women who had preterm and aterm birth. The sample consisted of case group and control group which were convenient to exclusion and inclusion criteria. Univariate analysis was used to observe the relationship between dependent and independent variable. The significance value was p ≤ 0.05. The data were analysed using SPSS.
Results: The research samples consisted of 89 case groups and 89 control groups. The case sample characteristic showed that 36% patients had overweight BMI; 62.9% patients had normal/hypotension; 69.7% patients gave birth to male baby; and 82% patients had no history of disease.There was no patient who used drugs and substance abuse (0%). Mothers aged 20 years old and older than 35 years old had OR = 2.13 (95% CI : 1.106-4.11) to become preterm birth. The primiparous women had risk for preterm birth 2.978 folds (95%, CI : 576-5.625) higher.
Conclusion: There was a relationship between maternal age and parity to preterm birth. There was no relationship between maternal education, maternal occupation, hemoglobin levels, history of obstetric complications, and multiple pregnancy to preterm birth.
World Health Organization. Preterm Birth. World Health Organization, https://www.who.int/news-room/fact-sheets/detail/preterm-birth (2018).
UNICEF. Maternal and Newborn Health Disparities Country Profiles. UNICEF, https://data.unicef.org/resources/maternal-newborn-health-disparities-country-profiles/ (2016).
Norman J, Greer I. Preterm Labour: Managing Risk in Clinical Practice. Cambridge: Cambridge University Press, 2005.
Schieve L, Tian L, Rankin K, et al. Population Impact of Preterm Birth and Low Birth Weight on Developmental Disabilities in US Children. Ann Epidemiol 2016; 26: 267–274.
Kozuki N, Lee A, Silveira M, et al. The Associations of Parity and Maternal Age with Small-for-Gestational-Age, Preterm, and Neonatal and Infant Mortality: a Meta-Analysis. BMC Public Health; 13. Epub ahead of print 2013. DOI: 10.1186/1471-2458-13-S3-S2.
Londero A, Rossetti E, Pittini C, et al. Maternal Age and the Risk of Adverse Pregnancy Outcomes: a Retrospective Cohort Study. BMC Pregnancy Childbirth; 19. Epub ahead of print 2019. DOI: https://doi.org/10.1186/s12884-019-2400-x.
El-Sayed A, Galea S. Temporal Changes in Socioeconomic Influences on Health: Maternal Education and Preterm Birth. Am J Public Health 2012; 102: 1715–21.
Casas M, Cordier S, Martinez D, et al. Maternal Occupation during Pregnancy, Birth Weight, and Length of Gestation: Combined Analysis of 13 European Birth Cohorts. Scand J Work Environ Health 2019; 45: 42–52.
Allen L. Biological Mechanisms that might Underlie Iron’s effects on Fetal Growth and Preterm Birth. J Nutr 2001; 131: 581S–289S.
Yang J, Baer RJ, Berghella V, et al. Recurrence of Preterm Birth and Early Term Birth. Obstet Gynecol 2016; 128: 364–372.
Kaur J, Kaur K. Obstetric Complications: Primiparity Vs. Multiparity. Eur J Exp Biol; 2.
Murray S, Stock S, Cowan S, et al. Spontaneous Preterm Birth Prevention in Multiple Pregnancy. Obstet Gynecol 2018; 20: 57–63.
Syarif A. Hubungan Usia dengan Kejadian Persalinan Preterm di RSUD Wonosari tahun. Politeknik Kesehatan Yogyakarta, 2017.
Ningrum N, Nurhamidi N, Yusti. Hubungan Umur Paritas dan Kejadian Anemia dengan Kejadian Persalinan Prematur di RSUD dr. H. Moch. Ansari Saleh Banjarmasin tahun 2016. Din Kesehat J Kebidanan dan Keperawatan; 8,https://ojs.dinamikakesehatan.unism.ac.id/index.php/dksm/article/view/238 (2017).
Hanifah A, Wahyuningsih H, Margono. Faktor-Faktor yang Berhubungan dengan Kejadian Persalinan Preterm di RSUD Wonosari tahun 2015-2016. Politeknik Kesehatan Yogyakarta, 2017.
Putri R. Hubungan Usia, Jumlah Kehamilan, dan Riwayat Abortus Spontan pada Ibu Hamil dengan Kejadian Abortus Spontan di Rumah Sakit Umum Aghisna Medika Kabupaten Cilacap. Universitas Muhammadiyah Surakarta, 2018.
Niswah F. Faktor Risiko Kejadian Persalinan Prematur (Studi Kasus di RSUD Tugurejo Semarang). Universitas Negeri Semarang, 2016.
Waldenström U, Cnattingius S, Vixner L, et al. Advanced Maternal Age Increases the Risk of Very Preterm Birth, Irrespective of Parity: a Population-based Register Study. BJOG 2017; 124: 1235–1244.
Chen K-H, Chen I-C, Yang Y-C, et al. The Trends and Associated Factors of Preterm Deliveries from 2001 to 2011 in Taiwan. Medicine (Baltimore) 2019; 98: e15060.
Saurel-Cubizolles M, Zeitlin J, Lelong N, et al. Employment, Working Conditions, and Preterm Birth: Results from the Europop Case-Control Survey. J Epidemiol Community Heal 2004; 58: 395–401.
Kumari S, Garg N, Kumar A, et al. Maternal and Severe Anaemia in Delivering Women is Associated with Risk of Preterm and Low Birth Weight: A Cross Sectional study from Jharkhand, India. One Heal 2019; 8: 100098.
Rahman MM, Abe SK, Rahman MS, et al. Maternal Anemia and Risk of Adverse Birth and Health Outcomes in Low- and Middle-Income Countries: Systematic Review and Meta-analysis. Am J Clin Nutr 2016; 103: 495–504.
Yuan X, Hu H, Zhang M, et al. Iron Deficiency in Late Pregnancy and its Associations with Birth Outcomes in Chinese Pregnant Women: A Retrospective Cohort Study. Nutr Metab (Lond); 116. Epub ahead of print 2019. DOI: 10.1186/s12986-019-0360-9.
Purisch SE, Turitz AL, Elovitz MA, et al. The Effect of Prior Term Birth on Risk of Recurrent Spontaneous Preterm Birth. Am J Perinatol 2018; 35: 380–384.
Zijl V, B K, BWJ M, et al. Prevention of Preterm Delivery: Current Challenges and Future Prospects. Int J Women’s Heal 2016; 2016: 633–645.
Ke L, Lin W, Liu Y, et al. Association of Induced Abortion with Preterm Birth Risk in First-Time Mothers. Sci Rep; 8, https://www.nature.com/articles/s41598-018-23695-7 (2018).
Bhattacharya S, Lowit A, Bhattacharya S, et al. Reproductive Outcomes following induced Abortion: a National Register-based Cohort Study in Scotland. BMJ Open; 2. Epub ahead of print 2012. DOI: 10.1136/bmjopen-2012-000911.
Sulistiarini D, Berliana SM. Faktor-Faktor yang mempengaruhi Kelahiran Prematur di Indonesia: Analisis Data Riskesdas 2013. lWIDYA Kesehat Dan Lingkung 2016; 1: 109–115.
AlBasri SF, Shouib GM, Bajouh OS, et al. Maternal and Neonatal Outcomes in Twin and Triplet Gestations in Western Saudi Arabia. Saudi Med J 2017; 38: 657–661.
Gashi A. Frequency of Premature Births in Twin Pregnancies in Kosovo. Crit Care Obstet Gynecol 2015; 1: 1–3.
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