Early- and Late-Onset Preeclampsia at a Tertiary Hospital in 2016
Downloads
Introduction: Preeclampsia is still one of the major causes of maternal morbidity and mortality worldwide. Preeclampsia nowadays has another classification, early-onset preeclampsia and late-onset preeclampsia. This study aimed to evaluate the differences between early-onset and late-onset preeclampsia in Dr. Soetomo General Hospital, Surabaya in 2016.
Methods: This was an analytic observational study, evaluating the difference between early- and late-onset preeclampsia in terms of maternal data, medical history, and obstetric history. The samples were taken from the medical record of Dr. Soetomo General Hospital, Surabaya from January until December 2016.
Results: In maternal data, early- and late-onset preeclampsia mostly happened in productive age, consisted of 34 patients of early-onset preeclampsia (77.3%) and 31 patients of late-onset preeclampsia (73.8%). Early-onset preeclampsia tended to happen in nullipara (42.2%) and primigravida (35.6%) women, and late-onset preeclampsia usually happened in multipara (43.9%) and multigravida (85.4%) women. In medical and obstetric history, early-onset preeclampsia mostly had a history of hypertension (61.7%), rather than late-onset preeclampsia (32.7%). Moreover, there were no significant differences in other variables.
Conclusion: Early-onset and late-onset preeclampsia had a significant difference in parity, gravidity, and hypertension disease.
Ahmed S, Fullerton J. Challenges of Reducing Maternal and Neonatal Mortality in Indonesia: Ways forward. Int J Gynecol Obstet 2019; 144: 1–3.
Aksornphusitaphong A, Phupong V. Risk Factors of Early and Late Onset Pre"Eclampsia. J Obstet Gynaecol Res 2013; 39: 627–631.
E. G, Akurati L, Radhika K. Early Onset and Late Onset Preeclampsia-Maternal and Perinatal Outcomes in a Rural Teritiary Health Center. Int J Reprod Contraception, Obstet Gynecol 2018; 7: 2266.
Roberts J, Bell M. If We Know so Much About Preeclampsia, Why Haven't We Cured The Disease? J Reprod Immunol 2013; 99: 1–9.
Lisonkova S, Joseph K. Incidence of Preeclampsia: Risk Factors and Outcomes Associated with Early- Versus Late-Onset Disease. Am J Obstet Gynecol 2013; 209: 544.e1-544.e12.
Valensise H, Vasapollo B, Gagliardi G, Novelli GP. Early and Late preeclampsia: Two Different Maternal Hemodynamic States in The Latent Phase of The Disease. Hypertension 2008; 52: 873–880.
Myatt L, Redman C., Staff A., Hansson S, Wilson ML, Laivouri H. Strategy for Standardization of Preeclampsia Research Study Design. Hyperrtension 2014; 63: 1293–1301.
Dekker G., Sibai B. The Immunology of Preeclampsia. Semin Perinatol 1999; 23: 24–33.
Luo Z, An N, Xu H, Larante A, Audibert F, Fraser WD. The Effects and Mechanisms of Primiparity in The Risk of Pree-Eclampsia: A Systematic Review. Paediatr Perinat Epidemiol 2007; 21: 36–45.
Robillard PY, Dekker G, Iacobelli S, Chaouat G. An Essay of Reflection: Why does Preeclampsia Exist in Humans, and Why are There such Huge Geographical Differences in Epidemiology? J Reprod Immunol 2016; 114: 44–47.
You SH, Cheng PJ, Chung TT, Kuo CF, Wu HM, Chu PH. Population-Based Trends and Risk Factors of Early- and Late-Onset Preeclampsia in Taiwan 2001-2014. BMC Pregnancy Childbirth 2018; 18: 1–11.
1. The journal allows the author to hold the copyright of the article without restrictions.
2. The journal allows the author(s) to retain publishing rights without restrictions
3. The formal legal aspect of journal publication accessibility refers to Creative Commons Atribution-Share Alike 4.0 (CC BY-SA).
