Clinical Profile of Hypertension in Diabetes Mellitus Patients at Surya Melati Muhammadiyah Hospital, Kediri, in 2021
Downloads
Highlights:
- This study presented the clinical profile of hypertension in patients with DM, providing regional data not previously reported in the literature. It emphasizes the value of implementing targeted interventions.
- Discussion of pathophysiological mechanisms explained the link between DM and hypertension.
Abstract
Introduction: The cardiologic and vascular consequences of both diabetes mellitus (DM) and hypertension often occur side by side in a high incidence worldwide. They are primarily caused by the significant overlap of microvascular and macrovascular aberrations, as well as several other factors, making them closely related to one another. A better understanding between these two is needed. This study examined the clinical profile of hypertension in DM patients at Surya Melati Muhammadiyah Hospital, Kediri, in 2021.
Methods: This study employed an observational, descriptive design. The population of the study was patients with DM and hypertension treated at Surya Melati Muhammadiyah Hospital, Kediri, in 2021. This study used a total sampling method. Diabetes mellitus, hypertension, age, and gender were the observed variables. All the necessary data were obtained from the patients’ medical records. All statistical data analyses were conducted using Microsoft Excel.
Results: A total of 520 DM patients were included, comprising 185 males and 335 females. Most of them were between 51 and 60 years old, with a total of 233 patients. A total of 277 DM patients with hypertension were included, comprising 89 males and 188 females. Most of them were between 51 and 60 years old, with a total of 121 patients.
Conclusion: The number of diabetes mellitus patients with hypertension exceeded that of diabetes mellitus patients without hypertension. There were more female patients than males. Most of them were elderly.
Iqbal AM, Jamal SF. Essential Hypertension. 2023 Jul 20. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 30969681. [PubMed]
Gabb G. What is hypertension? Australian Prescriber. 2020;43(4):108–9. [PubMed]
Iqbal AM, Jamal SF. Essential Hypertension. [Updated 2022 Jul 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-.
Mills KT, Stefanescu A, He J. The Global Epidemiology of Hypertension. Nature Reviews Nephrology. 2020;16(4):223–37. [Journal]
Princewel F, Cumber SN, Kimbi JA, Nkfusai CN, Keka EI, Viyoff VZ, et al. Prevalence and risk factors associated with hypertension among adults in a rural setting: The case of ombe, Cameroon. Pan African Medical Journal. 2019;34. [PubMed]
Paczkowska A, Hoffmann K, Kus K, Kopciuch D, Zaprutko T, Ratajczak P, Michalak M, Nowakowska E, Bryl W. Impact of patient knowledge on hypertension treatment adherence and efficacy: A single-centre study in Poland. Int J Med Sci. 2021 Jan 1;18(3):852-860. [PubMed]
Sapra A, Bhandari P. Diabetes Mellitus. 2022 Jun 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. [PubMed]
Dewi GA, Wibisono S, Pawana IP. Risk factors for lower extremity amputation in diabetic foot ulcer patients: A case-control study. JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga. 2020;11(2):83. [Journal]
International Diabetes Federation. IDF Diabetes Atlas Ninth Edition 2019. IDF. 2019 [IDF]
Ismail L, Materwala H, Al Kaabi J. Association of risk factors with type 2 diabetes: A systematic review. Comput Struct Biotechnol J. 2021 Mar 10;19:1759-1785. [ScienceDirect]
Lin X, Xu Y, Pan X, Xu J, Ding Y, Sun X, et al. Global, regional, and national burden and trend of diabetes in 195 countries and territories: An analysis from 1990 to 2025. Scientific Reports. 2020;10(1). [Journal]
Khan MA, Hashim MJ, King JK, Govender RD, Mustafa H, Al Kaabi J. Epidemiology of type 2 diabetes – global burden of disease and forecasted trends. Journal of Epidemiology and Global Health. 2019;10(1):107. [Springer]
Goyal R, Jialal I. Diabetes Mellitus Type 2. [Updated 2022 Jun 19]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022. [PubMed]
Sari Y, Isworo A, Upoyo AS, Taufik A, Setiyani R, Swasti KG, et al. The differences in health-related quality of life between younger and older adults and its associated factors in patients with type 2 diabetes mellitus in Indonesia. Health and Quality of Life Outcomes. 2021;19(1). [Journal]
Pangribowo S. Tetap Produktif, Atasi, dan Cegah Diabetes Melitus. INFODATIN, Pusat Data dan Informasi Kementerian Kesehatan RI [Internet]. 2020. [Kemkes]
Hung MJ. Diabetes, Hypertension and Cardiovascular Disease: Clinical Insights, Mechanisms and Pharmacotherapies. Medicina (Kaunas). 2024 Mar 30;60(4):566. [Journal]
Jia G, Sowers JR. Hypertension in diabetes: An update of basic mechanisms and clinical disease. Hypertension. 2021;78(5):1197–205. [Journal]
Huebschmann AG, Huxley RR, Kohrt WM, Zeitler P, Regensteiner JG, Reusch JE. Sex differences in the burden of type 2 diabetes and cardiovascular risk across the life course. Diabetologia. 2019;62(10):1761–72. [Springer]
Ong C. Characteristic of chronic complications in type 2 diabetic patient based on Asian perspective. Current Internal Medicine Research and Practice Surabaya Journal. 2022;3(1):13. [Journal]
Naha S, Gardner MJ, Khangura D, et al. Hypertension in Diabetes. [Updated 2021 Aug 7]. In: Feingold KR, Anawalt B, Blackman MR, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. [PubMed]
Naha S, Gardner MJ, Khangura D, et al. Hypertension in Diabetes. [Updated 2021 Aug 7]. In: Feingold KR, Anawalt B, Blackman MR, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.
Al Ghorani H, Götzinger F, Böhm M, Mahfoud F. Arterial hypertension – clinical trials update 2021. Nutrition, Metabolism and Cardiovascular Diseases. 2022;32(1):21–31. [ScienceDirect]
Wiendrati Roostarini J, Adi Soelistijo S, Novida H, Sutjahjo A, Wibisono S, Hendro Prajitno J, et al. Lipoprotein (a) and Arterial Stiffness in Patients with Diabetes Mellitus. The New Armenian Medical Journal. 2019;13:74–8. [ResearchGate]
Sutadji JT, Pranoto A, Prasetyo RV. Risk factors of chronic kidney disease (CKD) in type 2 diabetes mellitus (DM) patients at dr. soetomo general academic hospital, Surabaya. JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga. 2023;14(1):12–6. [Journal]
Melasari WP, Suharjono S, Samsulhadi W. Effect of atorvastatin in lipid profile changes and inflammation marker TNF-alpha on diabetes patient with dyslipidemia. Folia Medica Indonesiana. 2021;57(1):6. [Journal]
Copyright (c) 2025 Ahmad Zaidan Ni'am Abu Adha, Fahmi Adi Priyantoro

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
1. The journal allows the author to hold the copyright of the article without restrictions.
2. The journal allows the author(s) to retain publishing rights without restrictions
3. The formal legal aspect of journal publication accessibility refers to Creative Commons Atribution-Share Alike 4.0 (CC BY-SA).