PEMBERIAN AIR REBUSAN BAWANG BOMBAY (Allium Cepa L) DALAM MEREGULASI KADAR GLUKOSA DARAH MENCIT DENGAN DIABETES MELITUS

Ariska Putri Hidayathillah, I Ketut Sudiana, Ika Yuni Widyawati

= http://dx.doi.org/10.20473/cmsnj.v4i2.12727
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Abstract


Introduction: Diabetes mellitus is a degenerative disease with high prevalence that happens in many countries and high risk of causing death. The objective of this study is to know the effect of decoction by Allium cepa L on blood glucose level regulation in mice with diabetes mellitus.

Method: This study was used a true experimental pre post test design with 30 samples, 8-12 weeks old-male mice, and 20-30 grams in weight. The mices were divided into five groups (normal control group, diabetes control group without treatment, treatment group with 3 gram/kg of decoction, treatment group with 4 gram/kg of decoction and treatment group with 5 gram/kg of
decoction). The independent variable was Allium cepa L decoction (1cc) as a treatment, which is given per oral. Furthermore, the dependent variable was blood glucose level after 7 days treatment with Allium cepa L decoction.

Result: The result showed that there were some differences between the treatment group and the diabetes control group without treatment for blood glucose level after giving treatment with Allium cepa L decoction (p<0.005). in other hand, there was no significant result between the normal group and the treatment group for blood glucose level after giving treatment with Allium cepa L decoction 5 gram/kg bb (p>0.005). Allium cepa L contains many substances which has many function to regulate blood glucose level.

Discussion: It can be concluded that Allium cepa L decoction (5 gram/kg bb in 1 cc) is adequate for regulating blood glucose level in diabetes mellitus mice after 7 days treatment


Keywords


Diabetes mellitus, Allium cepa L decoction, blood glucose level

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References


Arief, I 2007, Lima Pilar Utama Pengelolaan DM, National Cardiovascular Center Harapan Kita, Diakses 09 Februari 2013, dari http://www.pjnhk.go.id/

Banerjee, S & Maulik, S 2002, ‘Effect Of Garlic On Cardiovascular Disorders: A Review’, Nutrition Jurnal, Vol. 1, No. 4, Hal. 8-9

Departemen Kesehatan Republik Indonesia, 2011, Integrasi Pengobatan Tradisional Dalam Sistem Kesehatan Nasional, Diakses 10 Februari 2013, dari http://depkes.go.id/index.php/berita/p

ress-release/1706-integrasipengobatan-tradisional-dalamsistem-kesehatan-nasional.html

Ganong, W 2008, Buku Ajar Fisiologi Kedokteran, EGC, JakartaGustina, R 2012, Aktivitas ekstrak, Fraksi Pelarut, Dan Senyawa Flavanoid Daun Sukun Terhadap Enzim α-Glukosidase Sebagai AntiDiabetes: Laporan Biokimia Departemen Biokimia Fakultas Matematika dan Ilmu Pengetahuan Alam Institut Pertanian Bogor, Bogor

Harmanto, N & Subroto, A 2007, Pilih Jamu dan Herbal Tanpa Efek Samping, Elex Media Komputindo, Jakarta

Hernawan, U & Setyawan, A 2003, ‘Review: Organosulphure Compound of Garlic (Allium sativum L.) and its Biological Activities’, Biofarmasi, Vol. 1, No. 2, Hal.: 70 Ji, et al. 2011, ‘Quercetin attenuates fasting and postprandial hyperglycemia in

animal models of Diabetes mellitus’, Nutrition Reseach And Practice, Vol. 2, No. 5, Hal. 107-111

Kartini, N 2012, Pengaruh Lama Penyeduhan dan Lama Penyimpanan Terhadap Aktivitas Teh Rosesla: Laporan Biokimia, Universitas Pendidikan Indonesia, Bandung

Lingga, L 2010, ‘Bawang Bombay’, Cerdas Memilih Sayuran, Agro Media Pustaka, Jakarta

Murtihapsari, 2008, Analisis Senyawa Kuersetin Bawang Bombay Aliium Cepa Melalui Uji Multifragmen Separatif Dan Spektrofotometris, Jurusan Kimia Fakultas MIPA Universitas Negeri Papua, Papua Barat

Pratita, N 2012, ‘Hubungan Dukungan Pasangan dan Health Locus of Control dengan Kepatuhan Dalam Menjalani ProsesPengobatan Pada Penderita Diabetes mellitus Tipe-2’, Jurnal Ilmiah Mahasiswa

Universitas Surabaya, Vol. 1, No. 1

Rahayu, M et al. 2006, ‘PemanfaatanTumbuhan Obat Secara Tradisional Oleh Masyarakat Lokal di Pulau Wawonii, Sulawesi Tenggara’, Biodiversitas, Vol. 7, No. 3, Hal.: 245-250

Ramdhani, S & Rakhmi 2008, ‘Pengaruh Ekstrak Etanol Daun Muntingia calabura L. Terhadap Kadar Glukosa Darah Mencit Jantan Dewasa’, Skripsi, Institut Tekhnologi Bogor, Bogor.

Subroto, A 2006, ‘Diabetes mellitus’, VCO Dosis Tepat Taklukkan Penyakit, Penebar Swadaya, Tangerang Wijayakusuma, H 2008, ‘Bawang Bombay’, Ramuan Herbal Penurun Kolesterol, Pustaka Bunda, Jakarta


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