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Submitted
11 January 2021
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11 January 2021
Published
31 December 2019
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Abstract

This study aimed to determine the relationship between mothers with history of diabetes mellitus with Infants with Anti-GAD65. This study was an observational analytic study with a cohort study design. The case studied was the relationship between maternal history of diabetes mellitus and infants with Anti-GAD65. This study was conducted at Jemursari Hospital in Surabaya. Sample examination was performed with a GAD65 autoimmune rapid test. Then, a statistical test was performed to determine its relationship with other variables. There was no relationship between mothers with history of diabetes mellitus and infants with Anti-GAD65, but there was a significant relationship between Anti-GDA65 Mothers with Infants with Anti-GAD65. Thus, there was a possibility of transplacental antibody transfer and viral infections during pregnancy that cause damage to pancreatic beta cells. History of diabetes mellitus was not related to infants with Anti-GAD65, but there was a relationship between Anti-GAD65 Mothers with Anti-GAD65 BAyi so that there is a transfer of transplacenta antibodies and viral infections during pregnancy that can cause damage to beta pancreatic cells in infants.

Keywords

Diabetes mellitus GAD65 transplacental antibodies virus infection pregnancy

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How to Cite
Salamy, N. F. W., Sari, G. M., Purwanto, B., & Sulistiawati, S. (2019). Correlation of Mothers with History of Diabetes Mellitus and Infants with Anti-GAD65. Folia Medica Indonesiana, 55(4), 301–305. https://doi.org/10.20473/fmi.v55i4.24474
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